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Protein
Submitted name:

Uncharacterized protein

Gene

Adam8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:Adam8Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107825 Adam8

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei408 – 432HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi210 ↔ 230PROSITE-ProRule annotation
Disulfide bondi364 ↔ 374PROSITE-ProRule annotation
Disulfide bondi382 ↔ 391PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PeptideAtlasiQ3UA33
PRIDEiQ3UA33

Structurei

3D structure databases

ProteinModelPortaliQ3UA33
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 144Peptidase M12BInterPro annotationAdd BLAST144
Domaini152 – 238DisintegrinInterPro annotationAdd BLAST87
Domaini360 – 392EGF-likeInterPro annotationAdd BLAST33

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3607 Eukaryota
ENOG410XX2M LUCA
HOVERGENiHBG103970

Family and domain databases

CDDicd04269 ZnMc_adamalysin_II_like, 1 hit
Gene3Di3.40.390.10, 1 hit
4.10.70.10, 1 hit
InterProiView protein in InterPro
IPR006586 ADAM_Cys-rich
IPR018358 Disintegrin_CS
IPR001762 Disintegrin_dom
IPR036436 Disintegrin_dom_sf
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR024079 MetalloPept_cat_dom_sf
IPR001590 Peptidase_M12B
IPR034027 Reprolysin_adamalysin
PfamiView protein in Pfam
PF08516 ADAM_CR, 1 hit
PF00200 Disintegrin, 1 hit
PF01421 Reprolysin, 1 hit
PRINTSiPR00289 DISINTEGRIN
SMARTiView protein in SMART
SM00608 ACR, 1 hit
SM00050 DISIN, 1 hit
SUPFAMiSSF57552 SSF57552, 1 hit
PROSITEiView protein in PROSITE
PS50215 ADAM_MEPRO, 1 hit
PS00427 DISINTEGRIN_1, 1 hit
PS50214 DISINTEGRIN_2, 1 hit
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 1 hit

Sequencei

Sequence statusi: Fragment.

Q3UA33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
KFYISRYANV TLENFLSWRE QNLQGQHPHD NVQLITGVDF IGSTVGLAKV
60 70 80 90 100
SALCSRHSGA VNQDHSKNSI GVASTMAHEL GHNLGMSHDE DIPGCYCPEP
110 120 130 140 150
REGGGCIMTE SIGSKFPRIF SRCSKIDLES FVTKPQTGCL TNVPDVNRFV
160 170 180 190 200
GGPVCGNLFV EHGEQCDCGT PQDCQNPCCN ATTCQLVKGA ECASGTCCHE
210 220 230 240 250
CKVKPAGEVC RLSKDKCDLE EFCDGRKPTC PEDAFQQNGT PCPGGYCFDG
260 270 280 290 300
SCPTLAQQCR DLWGPGARVA ADSCYTFSIP PGCNGRMYSG RINRCGALYC
310 320 330 340 350
EGGQKPLERS FCTFSSNHGV CHALGTGSNI DTFELVLQGT KCEEGKVCMD
360 370 380 390 400
GSCQDLRVYR SENCSAKCNN HGVCNHKREC HCHKGWAPPN CVQRLADVSD
410 420 430 440 450
EQAASTSLPV SVIVVLVILV AAMVIVAGIV IYRKAPRQIQ RRSVAPKPIS
460 470 480 490 500
GLSNPLFYTR DSSLPAKNRP PDPSETVSTN QPPRPIVKPK RPPPAPPGAV
510 520 530 540 550
SSSPLPVPVY APKIPNQFRP DPPTKPLPEL KPKQVKPTFA PPTPPVKPGT
560 570
GGTVPGATQG AGEPKVALKV PIQKR
Length:575
Mass (Da):61,725
Last modified:October 11, 2005 - v1
Checksum:i17AFBF2A1BFBF7BB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK151535 mRNA Translation: BAE30482.1
UniGeneiMm.15969

Similar proteinsi

Entry informationi

Entry nameiQ3UA33_MOUSE
AccessioniPrimary (citable) accession number: Q3UA33
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 18, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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