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Protein
Submitted name:

Interferon-induced protein with tetratricopeptide repeats 1B-like 2

Gene

Ifit1bl2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • defense response to virus Source: GO_Central

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon-induced protein with tetratricopeptide repeats 1B-like 2Imported
Gene namesi
Name:Ifit1bl2Imported
Synonyms:2010002M12RikImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:2148249 Ifit1bl2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000067297 Expressed in 159 organ(s), highest expression level in intestine

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000093816

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini144 – 282TPR_REGIONInterPro annotationAdd BLAST139
Repeati146 – 179TPRPROSITE-ProRule annotationAdd BLAST34
Repeati249 – 282TPRPROSITE-ProRule annotationAdd BLAST34
Domaini319 – 367TPR_REGIONInterPro annotationAdd BLAST49
Repeati334 – 367TPRPROSITE-ProRule annotationAdd BLAST34
Domaini429 – 462TPR_REGIONInterPro annotationAdd BLAST34
Repeati429 – 462TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili69 – 89Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1124 Eukaryota
COG0457 LUCA
GeneTreeiENSGT00390000013876
HOGENOMiHOG000001558
HOVERGENiHBG066330
OMAiMHNLMAY
OrthoDBiEOG091G06GX
TreeFamiTF342671

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF13176 TPR_7, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 7 hits
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 4 hits
PS50293 TPR_REGION, 3 hits

Sequencei

Sequence statusi: Complete.

Q3U687-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEQLLSPSNM SEESHKSHIH DSLDELRCHF TWELDIKDKH IHDLEIKISE
60 70 80 90 100
TEFRDPIYSI GMHNLLAYVR HLKGQQDEAL QSLKEAEALI QSEQLSKRSL
110 120 130 140 150
ATWGNCAWLH YHRGSLAEAQ VYLDKVEKVC KEFSSPFRYR LECAEMDCEE
160 170 180 190 200
GWALRKCGSQ NYTRAMACFE RALKVEPENP EYNAGYADVA YHLDYYDGNS
210 220 230 240 250
LQPLKKAVSV KPEDPYLKVL LALKLQDLRK TDEAEKHIKE ATLTISSQNN
260 270 280 290 300
IFGYVAKFYR RKGCVEEALG FLKKALETKP SSPYLHFQIG LCHKTQFFQM
310 320 330 340 350
KKATSRENRK RADQSCHLAI CHFKKTLELK PTYDRAYIDL AEVYAKNHQQ
360 370 380 390 400
KEAEDNFQEV LSMSNLGDYM QQEIHFRYGN FQQYYKKSEE AAITHYLKGL
410 420 430 440 450
KIEVTSHYRD KLLKALEELA EGRKEDHVLE SLSLLGLVCR LRGDTSEAMS
460
CYEKALRLTG AVNPEF
Length:466
Mass (Da):54,065
Last modified:October 11, 2005 - v1
Checksum:i5E260419AA33DC10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016791 Genomic DNA No translation available.
BC138202 mRNA Translation: AAI38203.1
AK136525 mRNA Translation: BAE23025.1
AK153247 mRNA Translation: BAE31838.1
RefSeqiNP_444447.1, NM_053217.2
XP_017173534.1, XM_017318045.1
UniGeneiMm.440727

Genome annotation databases

EnsembliENSMUST00000087357; ENSMUSP00000093816; ENSMUSG00000067297
ENSMUST00000112463; ENSMUSP00000108082; ENSMUSG00000067297
GeneIDi112419
UCSCiuc008hgs.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016791 Genomic DNA No translation available.
BC138202 mRNA Translation: AAI38203.1
AK136525 mRNA Translation: BAE23025.1
AK153247 mRNA Translation: BAE31838.1
RefSeqiNP_444447.1, NM_053217.2
XP_017173534.1, XM_017318045.1
UniGeneiMm.440727

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000093816

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000087357; ENSMUSP00000093816; ENSMUSG00000067297
ENSMUST00000112463; ENSMUSP00000108082; ENSMUSG00000067297
GeneIDi112419
UCSCiuc008hgs.1 mouse

Organism-specific databases

CTDi112419
MGIiMGI:2148249 Ifit1bl2

Phylogenomic databases

eggNOGiKOG1124 Eukaryota
COG0457 LUCA
GeneTreeiENSGT00390000013876
HOGENOMiHOG000001558
HOVERGENiHBG066330
OMAiMHNLMAY
OrthoDBiEOG091G06GX
TreeFamiTF342671

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000067297 Expressed in 159 organ(s), highest expression level in intestine

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF13176 TPR_7, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 7 hits
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 4 hits
PS50293 TPR_REGION, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ3U687_MOUSE
AccessioniPrimary (citable) accession number: Q3U687
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 7, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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