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UniProtKB - Q3U419 (Q3U419_MOUSE)
Protein
TYRO protein tyrosine kinase-binding protein
Gene
Tyrobp
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Recommended name: TYRO protein tyrosine kinase-binding proteinARBA annotationAlternative name(s): DNAX-activation protein 12ARBA annotation |
Gene namesi | Name:TyrobpImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:1277211, Tyrobp |
VEuPathDBi | HostDB:ENSMUSG00000030579 |
Subcellular locationi
Plasma membrane
- Cell membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Other locations
- Membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 43 – 64 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 27 | Sequence analysisAdd BLAST | 27 | |
ChainiPRO_5014309174 | 28 – 114 | TYRO protein tyrosine kinase-binding proteinSequence analysisAdd BLAST | 87 |
Keywords - PTMi
PhosphoproteinARBA annotationProteomic databases
MaxQBi | Q3U419 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000030579, Expressed in granulocyte and 259 other tissues |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 74 – 107 | DisorderedSequence analysisAdd BLAST | 34 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 89 – 107 | Polar residuesSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Belongs to the TYROBP family.ARBA annotation
Keywords - Domaini
SignalSequence analysisARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
HOGENOMi | CLU_141718_0_0_1 |
OMAi | VFCFATH |
OrthoDBi | 1508977at2759 |
PhylomeDBi | Q3U419 |
Family and domain databases
InterProi | View protein in InterPro IPR026200, Tyrobp |
PANTHERi | PTHR17554, PTHR17554, 1 hit |
i Sequence
Sequence statusi: Complete.
Q3U419-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGALEPSWCL LFLPVLLTVG GLSPVQAQSD TFPRCDCSSV SPGVLAGIVL
60 70 80 90 100
GDLVLTLLIA LAVYSLGRLV SRGQGTAEGT RKQHIAETES PYQELQGQRP
110
EVYSDLNTQR QYYR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK154480 mRNA Translation: BAE32616.1 |
RefSeqi | NP_035792.1, NM_011662.2 |
Genome annotation databases
GeneIDi | 22177 |
KEGGi | mmu:22177 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK154480 mRNA Translation: BAE32616.1 |
RefSeqi | NP_035792.1, NM_011662.2 |
3D structure databases
SMRi | Q3U419 |
ModBasei | Search... |
Proteomic databases
MaxQBi | Q3U419 |
Protocols and materials databases
Antibodypediai | 4010, 298 antibodies from 38 providers |
DNASUi | 22177 |
Genome annotation databases
GeneIDi | 22177 |
KEGGi | mmu:22177 |
Organism-specific databases
CTDi | 7305 |
MGIi | MGI:1277211, Tyrobp |
VEuPathDBi | HostDB:ENSMUSG00000030579 |
Phylogenomic databases
HOGENOMi | CLU_141718_0_0_1 |
OMAi | VFCFATH |
OrthoDBi | 1508977at2759 |
PhylomeDBi | Q3U419 |
Miscellaneous databases
BioGRID-ORCSi | 22177, 2 hits in 73 CRISPR screens |
ChiTaRSi | Tyrobp, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000030579, Expressed in granulocyte and 259 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR026200, Tyrobp |
PANTHERi | PTHR17554, PTHR17554, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3U419_MOUSE | |
Accessioni | Q3U419Primary (citable) accession number: Q3U419 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | May 25, 2022 | |
This is version 124 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |