UniProtKB - Q3U3R1 (Q3U3R1_MOUSE)
Protein
Submitted name:
CD137 antigen
Gene
Tnfrsf9
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- signaling receptor activity Source: InterPro
GO - Biological processi
- apoptotic process Source: InterPro
- negative regulation of cell population proliferation Source: InterPro
Keywordsi
Molecular function | ReceptorARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: CD137 antigenImported |
Gene namesi | Name:Tnfrsf9Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:1101059, Tnfrsf9 |
Subcellular locationi
Plasma Membrane
- external side of plasma membrane Source: InterPro
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 189 – 214 | HelicalSequence analysisAdd BLAST | 26 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_5010843375 | 24 – 256 | Sequence analysisAdd BLAST | 233 |
Proteomic databases
MaxQBi | Q3U3R1 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000028965, Expressed in placenta and 91 other tissues |
ExpressionAtlasi | Q3U3R1, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 47 – 85 | TNFR-CysInterPro annotationAdd BLAST | 39 | |
Domaini | 119 – 158 | TNFR-CysInterPro annotationAdd BLAST | 40 |
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
OMAi | CISGFHC |
OrthoDBi | 1102119at2759 |
Family and domain databases
CDDi | cd13410, TNFRSF9, 1 hit |
InterProi | View protein in InterPro IPR001368, TNFR/NGFR_Cys_rich_reg IPR020413, TNFR_9 IPR034020, TNFRSF9_N |
PANTHERi | PTHR47139:SF1, PTHR47139:SF1, 1 hit |
Pfami | View protein in Pfam PF00020, TNFR_c6, 1 hit |
PRINTSi | PR01924, TNFACTORR9 |
SMARTi | View protein in SMART SM00208, TNFR, 2 hits |
i Sequence
Sequence statusi: Complete.
Q3U3R1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGNNCYNVVV IVLLLVGCEK VGAVQNSCDN CQPGTFCRKY NPVCKSCPPS
60 70 80 90 100
TFSSIGGQPN CNICRVCAGY FRFKKFCSST HNAECECIEG FHCLGPQCTR
110 120 130 140 150
CEKDCRPGQE LTKQGCKTCS LGTFNDQNGT GVCRPWTNCS LDGRSVLKTG
160 170 180 190 200
TTEKDVVCGP PVVSFSPSTT ISVTPEGGPG GHSLQVLTLF LALTSALLLA
210 220 230 240 250
LIFITLLFSV LKWIRKKFPH IFKQPFKKTT GAAQEEDACS CRCPQEEEGG
GGGYEL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ832278 mRNA Translation: ABI30212.1 AK154625 mRNA Translation: BAE32724.1 |
RefSeqi | NP_001070977.1, NM_001077509.1 NP_035742.1, NM_011612.2 XP_011248530.1, XM_011250228.2 |
Genome annotation databases
GeneIDi | 21942 |
KEGGi | mmu:21942 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ832278 mRNA Translation: ABI30212.1 AK154625 mRNA Translation: BAE32724.1 |
RefSeqi | NP_001070977.1, NM_001077509.1 NP_035742.1, NM_011612.2 XP_011248530.1, XM_011250228.2 |
3D structure databases
SMRi | Q3U3R1 |
ModBasei | Search... |
Proteomic databases
MaxQBi | Q3U3R1 |
Protocols and materials databases
Antibodypediai | 3718, 1298 antibodies |
Genome annotation databases
GeneIDi | 21942 |
KEGGi | mmu:21942 |
Organism-specific databases
CTDi | 3604 |
MGIi | MGI:1101059, Tnfrsf9 |
Phylogenomic databases
OMAi | CISGFHC |
OrthoDBi | 1102119at2759 |
Miscellaneous databases
BioGRID-ORCSi | 21942, 0 hits in 19 CRISPR screens |
ChiTaRSi | Tnfrsf9, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000028965, Expressed in placenta and 91 other tissues |
ExpressionAtlasi | Q3U3R1, baseline and differential |
Family and domain databases
CDDi | cd13410, TNFRSF9, 1 hit |
InterProi | View protein in InterPro IPR001368, TNFR/NGFR_Cys_rich_reg IPR020413, TNFR_9 IPR034020, TNFRSF9_N |
PANTHERi | PTHR47139:SF1, PTHR47139:SF1, 1 hit |
Pfami | View protein in Pfam PF00020, TNFR_c6, 1 hit |
PRINTSi | PR01924, TNFACTORR9 |
SMARTi | View protein in SMART SM00208, TNFR, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3U3R1_MOUSE | |
Accessioni | Q3U3R1Primary (citable) accession number: Q3U3R1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | December 2, 2020 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |