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Protein
Submitted name:

Cyclin-K

Gene

Ccnk

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCyclinUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-112382 Formation of RNA Pol II elongation complex
R-MMU-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
R-MMU-674695 RNA Polymerase II Pre-transcription Events
R-MMU-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-MMU-6807505 RNA polymerase II transcribes snRNA genes
R-MMU-75955 RNA Polymerase II Transcription Elongation

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin-KImported
Gene namesi
Name:CcnkImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1276106 Ccnk

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000021258 Expressed in 191 organ(s), highest expression level in testis

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 149CYCLINInterPro annotationAdd BLAST95
Domaini158 – 278Cyclin_CInterPro annotationAdd BLAST121
Domaini162 – 256CYCLINInterPro annotationAdd BLAST95

Sequence similaritiesi

Belongs to the cyclin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0834 Eukaryota
COG5333 LUCA
GeneTreeiENSGT00760000119191
HOGENOMiHOG000220828
HOVERGENiHBG050836
OMAiNSYMSGE
OrthoDBiEOG091G0H4W
TreeFamiTF101010

Family and domain databases

CDDicd00043 CYCLIN, 2 hits
InterProiView protein in InterPro
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR004367 Cyclin_C-dom
IPR006671 Cyclin_N
PfamiView protein in Pfam
PF02984 Cyclin_C, 1 hit
PF00134 Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 2 hits
SM01332 Cyclin_C, 1 hit
SUPFAMiSSF47954 SSF47954, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q3U3M5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKENKENSSP SVTSANLDHT KPCWYWDKKD LAHTPSQLEG LDPATEARYR
60 70 80 90 100
REGARFIFDV GTRLGLHYDT LATGIIYFHR FYMFHSFKQF PRYVTGACCL
110 120 130 140 150
FLAGKVEETP KKCKDIIKTA RSLLNDVQFG QFGDDPKEEV MVLERILLQT
160 170 180 190 200
IKFDLQVEHP YQFLLKYAKQ LKGDKNKIQK LVQMAWTFVN DSLCTTLSLQ
210 220 230 240 250
WEPEIIAVAV MYLAGRLCKF EIQEWTSKPM YRRWWEQFVQ DVPVDVLEDI
260 270 280 290 300
CHQILDLYSQ GKQQMPHHTP HQLQQPPSLQ PTPQVPQGPQ SQPSQGSEAA
310 320 330 340 350
QPPQKDSQQS AQQQQQQAQQ PKKPSPQPSP PRQAKRAVVV SPKEENKATE
360 370 380 390 400
PPPPPKIPKL EATHPPLPPA HPPPDRKPPL APALGEAEAT GPVETSDLPK
410 420 430 440 450
VQIPPPAHPA PVHQPPPLPH RPPPPPPSSY MTGMSTTSSY MSGEGYQSLQ
460 470 480 490 500
SMMKTEGPSY GALPPAYGPP AHLTYHPHVY PPNPPPPPVP PPPASFPPPT
510 520 530 540 550
IPPPTPGYPP PPPTYNPNFP PPPPRLPPTH AVPPHPPPGL GLPPASYPPP
560 570 580
AVPPGGQPPV PPPIPPPGMP PVGGLGRAAW MR
Length:582
Mass (Da):64,350
Last modified:October 11, 2005 - v1
Checksum:i41462E8EB8EE7A61
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O88874CCNK_MOUSE
Cyclin-K
Ccnk
554Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC152059 Genomic DNA No translation available.
AK146711 mRNA Translation: BAE27377.1
AK154679 mRNA Translation: BAE32760.1
RefSeqiNP_033962.2, NM_009832.2
XP_006515506.1, XM_006515443.3
XP_006515507.1, XM_006515444.3
XP_006515508.1, XM_006515445.2
UniGeneiMm.474441

Genome annotation databases

EnsembliENSMUST00000101055; ENSMUSP00000098616; ENSMUSG00000021258
ENSMUST00000221167; ENSMUSP00000152784; ENSMUSG00000021258
GeneIDi12454
KEGGimmu:12454
UCSCiuc011yrr.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC152059 Genomic DNA No translation available.
AK146711 mRNA Translation: BAE27377.1
AK154679 mRNA Translation: BAE32760.1
RefSeqiNP_033962.2, NM_009832.2
XP_006515506.1, XM_006515443.3
XP_006515507.1, XM_006515444.3
XP_006515508.1, XM_006515445.2
UniGeneiMm.474441

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000101055; ENSMUSP00000098616; ENSMUSG00000021258
ENSMUST00000221167; ENSMUSP00000152784; ENSMUSG00000021258
GeneIDi12454
KEGGimmu:12454
UCSCiuc011yrr.1 mouse

Organism-specific databases

CTDi8812
MGIiMGI:1276106 Ccnk

Phylogenomic databases

eggNOGiKOG0834 Eukaryota
COG5333 LUCA
GeneTreeiENSGT00760000119191
HOGENOMiHOG000220828
HOVERGENiHBG050836
OMAiNSYMSGE
OrthoDBiEOG091G0H4W
TreeFamiTF101010

Enzyme and pathway databases

ReactomeiR-MMU-112382 Formation of RNA Pol II elongation complex
R-MMU-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
R-MMU-674695 RNA Polymerase II Pre-transcription Events
R-MMU-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-MMU-6807505 RNA polymerase II transcribes snRNA genes
R-MMU-75955 RNA Polymerase II Transcription Elongation

Miscellaneous databases

ChiTaRSiCcnk mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021258 Expressed in 191 organ(s), highest expression level in testis

Family and domain databases

CDDicd00043 CYCLIN, 2 hits
InterProiView protein in InterPro
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR004367 Cyclin_C-dom
IPR006671 Cyclin_N
PfamiView protein in Pfam
PF02984 Cyclin_C, 1 hit
PF00134 Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 2 hits
SM01332 Cyclin_C, 1 hit
SUPFAMiSSF47954 SSF47954, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiQ3U3M5_MOUSE
AccessioniPrimary (citable) accession number: Q3U3M5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 10, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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