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Entry version 112 (16 Oct 2019)
Sequence version 1 (11 Oct 2005)
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Protein

Protein transport protein Sec24A

Gene

Sec24a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi428ZincBy similarity1
Metal bindingi431ZincBy similarity1
Metal bindingi449ZincBy similarity1
Metal bindingi452ZincBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processER-Golgi transport, Protein transport, Transport
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-204005 COPII-mediated vesicle transport
R-MMU-2132295 MHC class II antigen presentation
R-MMU-5694530 Cargo concentration in the ER
R-MMU-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein transport protein Sec24ACurated
Alternative name(s):
SEC24-related protein A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Sec24aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1924621 Sec24a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002051541 – 1090Protein transport protein Sec24AAdd BLAST1090

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q3U2P1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q3U2P1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q3U2P1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3U2P1

PeptideAtlas

More...
PeptideAtlasi
Q3U2P1

PRoteomics IDEntifications database

More...
PRIDEi
Q3U2P1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q3U2P1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3U2P1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000036391 Expressed in 237 organ(s), highest expression level in liver

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q3U2P1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q3U2P1 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1.

Interacts with TMED2.

Interacts (as part of the Sec23/24 complex) with SEC22B; recruits SEC22B into COPII-coated vesicles for its transport from the endoplasmic reticulum to the Golgi.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
218649, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q3U2P1, 1 interactor

Molecular INTeraction database

More...
MINTi
Q3U2P1

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000104725

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q3U2P1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati963 – 1036Gelsolin-likeSequence analysisAdd BLAST74

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni428 – 452Zinc finger-likeAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi54 – 235Pro-richAdd BLAST182

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SEC23/SEC24 family. SEC24 subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1985 Eukaryota
COG5028 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182924

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3U2P1

KEGG Orthology (KO)

More...
KOi
K14007

Database of Orthologous Groups

More...
OrthoDBi
330236at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q3U2P1

TreeFam database of animal gene trees

More...
TreeFami
TF350406

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01479 Sec24-like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.20.10, 1 hit
3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR007123 Gelsolin-like_dom
IPR036180 Gelsolin-like_dom_sf
IPR006900 Sec23/24_helical_dom
IPR036175 Sec23/24_helical_dom_sf
IPR006896 Sec23/24_trunk_dom
IPR012990 Sec23_24_beta_S
IPR041742 Sec24-like_trunk_dom
IPR036465 vWFA_dom_sf
IPR006895 Znf_Sec23_Sec24
IPR036174 Znf_Sec23_Sec24_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00626 Gelsolin, 1 hit
PF08033 Sec23_BS, 1 hit
PF04815 Sec23_helical, 1 hit
PF04811 Sec23_trunk, 1 hit
PF04810 zf-Sec23_Sec24, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53300 SSF53300, 1 hit
SSF81811 SSF81811, 1 hit
SSF82754 SSF82754, 1 hit
SSF82919 SSF82919, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q3U2P1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAQPRIPAAR GAAASLQAQN GAASASGSPY TNGPVHNTLM SPQVSSSQGY
60 70 80 90 100
DSQPPGSYPR PMPAKTLNPF SAQSNYGGSQ GSGQTLNSPL VTSGPVLPSL
110 120 130 140 150
HSGPVPRMPL PTSQNPAATP MPSGSFLPGA NPPPPLNWQY NYPSTGPQTN
160 170 180 190 200
HFPHVAPPTL PGNPNLTADH QYVSSGDPAL QTSFKKPGSA LPLQNPPLPP
210 220 230 240 250
TFQPGAPPGP PPAGGPPPSR GPAPQKTPPR AAPPPSFNSA VNQEGITSNA
260 270 280 290 300
NNGSTAAHNT YDEIEGGGFL ATPQLVNQNP KTSRSVGSAY PSLPPGYQNS
310 320 330 340 350
APPVAGMPPP SLSYPSGPQA FTQTPLGANH LTASMSGLSL HPEGLRVVNL
360 370 380 390 400
LQERNMLPST PLQPPVPNLL EDIQKLNCNP ELFRCTLTSV PQTQALLNKA
410 420 430 440 450
KLPLGLLLHP FKDLVQLPVV TSSTIVRCRS CRTYINPFVN FLDQRRWKCN
460 470 480 490 500
LCYRVNDVPE EFMYNPLTRV YGEPHKRPEV QNATIEFMAP SEYMLRPPQP
510 520 530 540 550
PVYLFVFDVS HNAIETGYLN SVCQSLLDNL DLLPGNTRTK IGFITFDSTI
560 570 580 590 600
HFYSLQEGLS QPQMLIVSDI DDVFIPMPEN LLVNLNESKE LVQDLLKTLP
610 620 630 640 650
QMFTKTLETQ SALGPALQAA FKLISPTGGR MSVFQTQLPT LGVGALKPRE
660 670 680 690 700
EPNQRSSAKE IHLTPSTDFY KKLALDCSGQ QAAVDLFLLS GQYSDLASLG
710 720 730 740 750
CISRYSAGSV YYYPSYHHQH NPVQVQKLQK ELHRYLTRKI GFEAVMRIRC
760 770 780 790 800
TKGLSIHTFH GNFFVRSTDL LSLPNVNPDA GYAVQMSVEE SLTDTQLVSF
810 820 830 840 850
QSALLYTSSK GERRIRVHTL CLPVVSTLNE VFLGADVQAI SGLLANMAVD
860 870 880 890 900
RSVTASLSDA RDALVNAVID SLSAYRSSVL SGQQPGLMVP FSLRLFPLFV
910 920 930 940 950
LALLKQKSFQ TGTSIRLDER IFAMCQVKSQ PLVHLMLTTH PSLYRVDNLS
960 970 980 990 1000
DEGALNINDR TIPQPPILQL SVEKLSRDGA FLMDAGSLLM LWVGRNCSQN
1010 1020 1030 1040 1050
FLSQVLGVQN YASIPQTMTD LPELDTPESA RIAAFISWLR EQRPFFPVLY
1060 1070 1080 1090
VIREESLMKA AFLQSLVEDR TESALSYYEF LLHIQQQVNK
Length:1,090
Mass (Da):118,782
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i392F9E2B4F8CF670
GO
Isoform 2 (identifier: Q3U2P1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     572-592: DVFIPMPENLLVNLNESKELV → GMCYTQTHSTSWRIVPFRNVS
     593-1090: Missing.

Note: No experimental confirmation available.
Show »
Length:592
Mass (Da):63,411
Checksum:iAF6971A12926A119
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2AA71A2AA71_MOUSE
Protein transport protein Sec24A
Sec24a
1,089Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2AA72A2AA72_MOUSE
Protein transport protein Sec24A
Sec24a
591Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC26319 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti416Missing in BAE37580 (PubMed:16141072).Curated1
Sequence conflicti939T → K in BAC26319 (PubMed:16141072).Curated1
Sequence conflicti1038W → R in BAC26319 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016990572 – 592DVFIP…SKELV → GMCYTQTHSTSWRIVPFRNV S in isoform 2. 1 PublicationAdd BLAST21
Alternative sequenceiVSP_016991593 – 1090Missing in isoform 2. 1 PublicationAdd BLAST498

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK029139 mRNA Translation: BAC26319.1 Sequence problems.
AK155182 mRNA Translation: BAE33099.1
AK162795 mRNA Translation: BAE37062.1
AK163998 mRNA Translation: BAE37580.1
AL645602 Genomic DNA No translation available.
BC117905 mRNA Translation: AAI17906.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS24660.2 [Q3U2P1-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001277714.1, NM_001290785.1
NP_780464.2, NM_175255.3 [Q3U2P1-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000064297; ENSMUSP00000068065; ENSMUSG00000036391 [Q3U2P1-2]
ENSMUST00000109097; ENSMUSP00000104725; ENSMUSG00000036391 [Q3U2P1-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
77371

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:77371

UCSC genome browser

More...
UCSCi
uc007iui.1 mouse [Q3U2P1-1]
uc007iul.1 mouse [Q3U2P1-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK029139 mRNA Translation: BAC26319.1 Sequence problems.
AK155182 mRNA Translation: BAE33099.1
AK162795 mRNA Translation: BAE37062.1
AK163998 mRNA Translation: BAE37580.1
AL645602 Genomic DNA No translation available.
BC117905 mRNA Translation: AAI17906.1
CCDSiCCDS24660.2 [Q3U2P1-1]
RefSeqiNP_001277714.1, NM_001290785.1
NP_780464.2, NM_175255.3 [Q3U2P1-1]

3D structure databases

SMRiQ3U2P1
ModBaseiSearch...

Protein-protein interaction databases

BioGridi218649, 2 interactors
IntActiQ3U2P1, 1 interactor
MINTiQ3U2P1
STRINGi10090.ENSMUSP00000104725

PTM databases

iPTMnetiQ3U2P1
PhosphoSitePlusiQ3U2P1

Proteomic databases

EPDiQ3U2P1
jPOSTiQ3U2P1
MaxQBiQ3U2P1
PaxDbiQ3U2P1
PeptideAtlasiQ3U2P1
PRIDEiQ3U2P1

Genome annotation databases

EnsembliENSMUST00000064297; ENSMUSP00000068065; ENSMUSG00000036391 [Q3U2P1-2]
ENSMUST00000109097; ENSMUSP00000104725; ENSMUSG00000036391 [Q3U2P1-1]
GeneIDi77371
KEGGimmu:77371
UCSCiuc007iui.1 mouse [Q3U2P1-1]
uc007iul.1 mouse [Q3U2P1-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10802
MGIiMGI:1924621 Sec24a

Phylogenomic databases

eggNOGiKOG1985 Eukaryota
COG5028 LUCA
GeneTreeiENSGT00950000182924
InParanoidiQ3U2P1
KOiK14007
OrthoDBi330236at2759
PhylomeDBiQ3U2P1
TreeFamiTF350406

Enzyme and pathway databases

ReactomeiR-MMU-204005 COPII-mediated vesicle transport
R-MMU-2132295 MHC class II antigen presentation
R-MMU-5694530 Cargo concentration in the ER
R-MMU-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Sec24a mouse

Protein Ontology

More...
PROi
PR:Q3U2P1

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000036391 Expressed in 237 organ(s), highest expression level in liver
ExpressionAtlasiQ3U2P1 baseline and differential
GenevisibleiQ3U2P1 MM

Family and domain databases

CDDicd01479 Sec24-like, 1 hit
Gene3Di3.40.20.10, 1 hit
3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR007123 Gelsolin-like_dom
IPR036180 Gelsolin-like_dom_sf
IPR006900 Sec23/24_helical_dom
IPR036175 Sec23/24_helical_dom_sf
IPR006896 Sec23/24_trunk_dom
IPR012990 Sec23_24_beta_S
IPR041742 Sec24-like_trunk_dom
IPR036465 vWFA_dom_sf
IPR006895 Znf_Sec23_Sec24
IPR036174 Znf_Sec23_Sec24_sf
PfamiView protein in Pfam
PF00626 Gelsolin, 1 hit
PF08033 Sec23_BS, 1 hit
PF04815 Sec23_helical, 1 hit
PF04811 Sec23_trunk, 1 hit
PF04810 zf-Sec23_Sec24, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
SSF81811 SSF81811, 1 hit
SSF82754 SSF82754, 1 hit
SSF82919 SSF82919, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSC24A_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3U2P1
Secondary accession number(s): A2AA70
, A2AA73, A4FUV4, Q3TQ05, Q3TRG7, Q8BIS0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: October 11, 2005
Last modified: October 16, 2019
This is version 112 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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