UniProtKB - Q3TYB2 (Q3TYB2_MOUSE)
Protein
Neurogenic differentiation factor
Gene
Neurod2
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- protein dimerization activity Source: InterPro
- sequence-specific double-stranded DNA binding Source: Ensembl
GO - Biological processi
- cell differentiation Source: UniProtKB-KW
- nervous system development Source: UniProtKB-KW
- regulation of neuron differentiation Source: InterPro
- regulation of synapse maturation Source: InterPro
- regulation of transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | ActivatorARBA annotation, Developmental proteinUniRule annotationARBA annotation, DNA-bindingUniRule annotationARBA annotation |
Biological process | DifferentiationUniRule annotationARBA annotation, NeurogenesisUniRule annotationARBA annotation, Transcription, Transcription regulationUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Neurogenic differentiation factorUniRule annotation |
Gene namesi | Name:Neurod2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:107755, Neurod2 |
Subcellular locationi
Nucleus
- Nucleus UniRule annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusUniRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000038255, Expressed in cortical plate and 87 other tissues |
ExpressionAtlasi | Q3TYB2, baseline and differential |
Family & Domainsi
Phylogenomic databases
HOGENOMi | CLU_055134_0_1_1 |
OMAi | HDMHLHH |
OrthoDBi | 1096531at2759 |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR032649, Neurod2 IPR022575, Neurogenic_DUF IPR016637, TF_bHLH_NeuroD |
PANTHERi | PTHR19290:SF83, PTHR19290:SF83, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit PF12533, Neuro_bHLH, 1 hit |
PIRSFi | PIRSF015618, bHLH_NeuroD, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
Q3TYB2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLTRLFSEPG LLSDVPKFAS WGDGDDDEPR SDKGDAPPQP PPAPGSGAPG
60 70 80 90 100
PARAAKPVSL RGGEEIPEPT LAEVKEEGEL GGEEEEEEEE EEGLDEAEGE
110 120 130 140 150
RPKKRGPKKR KMTKARLERS KLRRQKANAR ERNRMHDLNA ALDNLRKVVP
160 170 180 190 200
CYSKTQKLSK IETLRLAKNY IWALSEILRS GKRPDLVSYV QTLCKGLSQP
210 220 230 240 250
TTNLVAGCLQ LNSRNFLTEQ GADGAGRFHG SGGPFAMHPY PYPCSRLAGA
260 270 280 290 300
QCQAAGGLGG GAAHALRTHG YCAAYETLYA AAGGGGASPD YNSSEYEGPL
310 320 330 340 350
SPPLCLNGNF SLKQDSSPDH EKSYHYSMHY SALPGSRPTG HGLVFGSSAV
360 370 380
RGGVHSENLL SYDMHLHHDR GPMYEELNAF FHN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK158767 mRNA Translation: BAE34651.1 |
RefSeqi | NP_035025.3, NM_010895.3 |
Genome annotation databases
GeneIDi | 18013 |
KEGGi | mmu:18013 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK158767 mRNA Translation: BAE34651.1 |
RefSeqi | NP_035025.3, NM_010895.3 |
3D structure databases
SMRi | Q3TYB2 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | Q3TYB2 |
PRIDEi | Q3TYB2 |
Protocols and materials databases
Antibodypediai | 16207, 198 antibodies |
DNASUi | 18013 |
Genome annotation databases
GeneIDi | 18013 |
KEGGi | mmu:18013 |
Organism-specific databases
CTDi | 4761 |
MGIi | MGI:107755, Neurod2 |
Phylogenomic databases
HOGENOMi | CLU_055134_0_1_1 |
OMAi | HDMHLHH |
OrthoDBi | 1096531at2759 |
Miscellaneous databases
BioGRID-ORCSi | 18013, 1 hit in 52 CRISPR screens |
ChiTaRSi | Neurod2, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000038255, Expressed in cortical plate and 87 other tissues |
ExpressionAtlasi | Q3TYB2, baseline and differential |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR032649, Neurod2 IPR022575, Neurogenic_DUF IPR016637, TF_bHLH_NeuroD |
PANTHERi | PTHR19290:SF83, PTHR19290:SF83, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit PF12533, Neuro_bHLH, 1 hit |
PIRSFi | PIRSF015618, bHLH_NeuroD, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3TYB2_MOUSE | |
Accessioni | Q3TYB2Primary (citable) accession number: Q3TYB2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | April 7, 2021 | |
This is version 139 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |