UniProtKB - Q3TWM9 (Q3TWM9_MOUSE)
Protein
Submitted name:
Uncharacterized protein
Gene
Psap
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Biological processi
- adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway Source: UniProtKB-UniRule
- regulation of lipid metabolic process Source: UniProtKB-UniRule
- sphingolipid metabolic process Source: UniProtKB-UniRule
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:PsapImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:97783, Psap |
Subcellular locationi
Extracellular region or secreted
- Secreted ARBA annotation
Extracellular region or secreted
- extracellular space Source: UniProtKB-UniRule
Lysosome
- lysosome Source: InterPro
Keywords - Cellular componenti
SecretedARBA annotationPTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 36 ↔ 111 | UniRule annotation | ||
Disulfide bondi | 39 ↔ 105 | UniRule annotation | ||
Disulfide bondi | 67 ↔ 79 | UniRule annotation | ||
Disulfide bondi | 170 ↔ 243 | UniRule annotation | ||
Disulfide bondi | 173 ↔ 237 | UniRule annotation | ||
Disulfide bondi | 202 ↔ 213 | UniRule annotation | ||
Disulfide bondi | 287 ↔ 360 | UniRule annotation | ||
Disulfide bondi | 290 ↔ 354 | UniRule annotation | ||
Disulfide bondi | 318 ↔ 329 | UniRule annotation | ||
Disulfide bondi | 412 ↔ 485 | UniRule annotation | ||
Disulfide bondi | 415 ↔ 479 | UniRule annotation | ||
Disulfide bondi | 443 ↔ 454 | UniRule annotation |
Keywords - PTMi
Disulfide bondUniRule annotationARBA annotation, GlycoproteinARBA annotationProteomic databases
PeptideAtlasi | Q3TWM9 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 31 | Saposin A-typeInterPro annotationAdd BLAST | 31 | |
Domaini | 32 – 115 | Saposin B-typeInterPro annotationAdd BLAST | 84 | |
Domaini | 166 – 247 | Saposin B-typeInterPro annotationAdd BLAST | 82 | |
Domaini | 283 – 364 | Saposin B-typeInterPro annotationAdd BLAST | 82 | |
Domaini | 408 – 489 | Saposin B-typeInterPro annotationAdd BLAST | 82 | |
Domaini | 491 – 527 | Saposin A-typeInterPro annotationAdd BLAST | 37 |
Keywords - Domaini
RepeatARBA annotation, SignalARBA annotationFamily and domain databases
InterProi | View protein in InterPro IPR003119, SAP_A IPR007856, SapB_1 IPR008138, SapB_2 IPR008373, Saposin IPR011001, Saposin-like IPR021165, Saposin_chordata IPR008139, SaposinB_dom |
Pfami | View protein in Pfam PF02199, SapA, 2 hits PF05184, SapB_1, 3 hits PF03489, SapB_2, 4 hits |
PIRSFi | PIRSF002431, Saposin, 1 hit |
PRINTSi | PR01797, SAPOSIN |
SMARTi | View protein in SMART SM00162, SAPA, 2 hits SM00741, SapB, 4 hits |
SUPFAMi | SSF47862, SSF47862, 3 hits |
PROSITEi | View protein in PROSITE PS51110, SAP_A, 2 hits PS50015, SAP_B, 4 hits |
i Sequence
Sequence statusi: Fragment.
Q3TWM9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GSAVLCRDVK TAVDCGAVKH CQQMVWSKPT AKSLPCDICK TVVTEAGNLL
60 70 80 90 100
KDNATQEEIL HYLEKTCEWI HDSSLSASCK EVVDSYLPVI LDMIKGEMSN
110 120 130 140 150
PGEVCSALNL CQSLQEYLAE QNQKQLESNK IPEVDMARVV APFMSNIPLL
160 170 180 190 200
LYPQDHPRSQ PQPKANEDVC QDCMKLVSDV QTAVKTNSSF IQGFVDHVKE
210 220 230 240 250
DCDRLGPGVS DICKNYVDQY SEVCVQMLMH MQPKEICVLA GFCNEVKRVP
260 270 280 290 300
MKTLVPATET IKNILPALEM MDPYEQNLVQ AHNVILCQTC QFVMNKFSEL
310 320 330 340 350
IVNNATEELL VKGLSNACAL LPDPARTKCQ EVVGTFGPSL LDIFIHEVNP
360 370 380 390 400
SSLCGVIGLC AARPELVEAL EQPAPAIVSA LLKEPTPPKQ PAQPKQSALP
410 420 430 440 450
AHVPPQKNGG FCEVCKKLVL YLEHNLEKNS TKEEILAALE KGCSFLPDPY
460 470 480 490 500
QKQCDDFVAE YEPLLLEILV EVMDPGFVCS KIGVCPSAYK LLLGTEKCVW
510 520
GPSYWCQNME TAARCNAVDH CKRHVWN
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK159622 mRNA Translation: BAE35237.1 |
RefSeqi | NP_001139596.1, NM_001146124.1 |
Genome annotation databases
GeneIDi | 19156 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK159622 mRNA Translation: BAE35237.1 |
RefSeqi | NP_001139596.1, NM_001146124.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q3TWM9 |
Genome annotation databases
GeneIDi | 19156 |
Organism-specific databases
CTDi | 5660 |
MGIi | MGI:97783, Psap |
Miscellaneous databases
BioGRID-ORCSi | 19156, 0 hits in 17 CRISPR screens |
ChiTaRSi | Psap, mouse |
SOURCEi | Search... |
Gene expression databases
Genevisiblei | Q3TWM9, MM |
Family and domain databases
InterProi | View protein in InterPro IPR003119, SAP_A IPR007856, SapB_1 IPR008138, SapB_2 IPR008373, Saposin IPR011001, Saposin-like IPR021165, Saposin_chordata IPR008139, SaposinB_dom |
Pfami | View protein in Pfam PF02199, SapA, 2 hits PF05184, SapB_1, 3 hits PF03489, SapB_2, 4 hits |
PIRSFi | PIRSF002431, Saposin, 1 hit |
PRINTSi | PR01797, SAPOSIN |
SMARTi | View protein in SMART SM00162, SAPA, 2 hits SM00741, SapB, 4 hits |
SUPFAMi | SSF47862, SSF47862, 3 hits |
PROSITEi | View protein in PROSITE PS51110, SAP_A, 2 hits PS50015, SAP_B, 4 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3TWM9_MOUSE | |
Accessioni | Q3TWM9Primary (citable) accession number: Q3TWM9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | December 2, 2020 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |