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UniProtKB - Q3TWI9 (CSCL2_MOUSE)

Entry version 107 (12 Aug 2020)
Sequence version 1 (11 Oct 2005)
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Protein

CSC1-like protein 2

Gene

Tmem63b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as an osmosensitive calcium-permeable cation channel (PubMed:27045885, PubMed:31243992). Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion (PubMed:30382938).3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel
Biological processIon transport, Transport
LigandCalcium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CSC1-like protein 2
Alternative name(s):
Transmembrane protein 63B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tmem63b
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2387609, Tmem63b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei41 – 61HelicalSequence analysisAdd BLAST21
Transmembranei158 – 178HelicalSequence analysisAdd BLAST21
Transmembranei203 – 223HelicalSequence analysisAdd BLAST21
Transmembranei435 – 455HelicalSequence analysisAdd BLAST21
Transmembranei481 – 501HelicalSequence analysisAdd BLAST21
Transmembranei521 – 541HelicalSequence analysisAdd BLAST21
Transmembranei560 – 580HelicalSequence analysisAdd BLAST21
Transmembranei630 – 650HelicalSequence analysisAdd BLAST21
Transmembranei678 – 698HelicalSequence analysisAdd BLAST21
Transmembranei711 – 731HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002807291 – 832CSC1-like protein 2Add BLAST832

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei111PhosphoserineCombined sources1
Modified residuei113PhosphoserineCombined sources1
Modified residuei114PhosphoserineCombined sources1
Modified residuei115PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q3TWI9

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q3TWI9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q3TWI9

PeptideAtlas

More...PeptideAtlasi		Q3TWI9

PRoteomics IDEntifications database

More...PRIDEi		Q3TWI9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q3TWI9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q3TWI9

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q3TWI9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000036026, Expressed in retinal neural layer and 278 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q3TWI9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q3TWI9, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		230322, 3 interactors

Protein interaction database and analysis system

More...IntActi		Q3TWI9, 1 interactor

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000109151

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q3TWI9, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CSC1 (TC 1.A.17) family. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1134, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000157084

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_015647_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q3TWI9

KEGG Orthology (KO)

More...KOi		K21989

Identification of Orthologs from Complete Genome Data

More...OMAi		WLWVHTI

Database of Orthologous Groups

More...OrthoDBi		395194at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q3TWI9

TreeFam database of animal gene trees

More...TreeFami		TF324300

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR032880, Csc1_N
IPR027815, PHM7_cyt
IPR003864, RSN1_7TM

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14703, PHM7_cyt, 1 hit
PF02714, RSN1_7TM, 1 hit
PF13967, RSN1_TM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q3TWI9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLPFLLATLG TAALNSSNPK DYCYSARIRS TVLQGLPFGG VPTVLALDFM 
        60         70         80         90        100
CFLALLFLFS ILRKVAWDYG RLALVTDADR LRRQERERVE QEYVASAMHG 
       110        120        130        140        150
DSHDRYERLT SVSSSVDFDQ RDNGFCSWLT AIFRIKDDEI RDKCGGDAVH 
       160        170        180        190        200
YLSFQRHIIG LLVVVGVLSV GIVLPVNFSG DLLENNAYSF GRTTIANLKS 
       210        220        230        240        250
GNNLLWLHTS FAFLYLLLTV YSMRRHTSKM RYKEDDLVKR TLFINGISKY 
       260        270        280        290        300
AESEKIKKHF EEAYPNCTVL EARPCYNVAR LMFLDAERKK AERGKLYFTN 
       310        320        330        340        350
LQSKENVPAM INPKPCGHLC CCVVRGCEQV EAIEYYTKLE QRLKEDYRRE 
       360        370        380        390        400
KEKVNEKPLG MAFVTFHNET ITAIILKDFN VCKCQGCTCR GEPRASSCSE 
       410        420        430        440        450
ALHISNWTVT YAPDPQNIYW EHLSIRGFIW WLRCLVINVV LFILLFFLTT 
       460        470        480        490        500
PAIIITTMDK FNVTKPVEYL NNPIITQFFP TLLLWCFSAL LPTIVYYSAF 
       510        520        530        540        550
FEAHWTRSGE NRTTMHKCYT FLIFMVLLLP SLGLSSLDLF FRWLFDKKFL 
       560        570        580        590        600
AEAAIRFECV FLPDNGAFFV NYVIASAFIG NAMDLLRIPG LLMYMIRLCL 
       610        620        630        640        650
ARSAAERRNV KRHQAYEFQF GAAYAWMMCV FTVVMTYSIT CPIIVPFGLM 
       660        670        680        690        700
YMLLKHLVDR YNLYYAYLPA KLDKKIHSGA VNQVVAAPIL CLFWLLFFST 
       710        720        730        740        750
MRTGFLAPTS MFTFVVLVIT IVICLCHVCF GHFKYLSAHN YKIEHTETDA 
       760        770        780        790        800
VSSRSNGRPP TAGAVPKSAK YIAQVLQDSE GDGDGDGAPG SSGDEPPSSS 
       810        820        830 
SQDEELLMPP DGLTDTDFQS CEDSLIENEI HQ
Length:832
Mass (Da):94,775
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE162259652DAE89C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3Z2D8D3Z2D8_MOUSE
CSC1-like protein 2
Tmem63b
309Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YY83D3YY83_MOUSE
CSC1-like protein 2
Tmem63b
264Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3Z0P2D3Z0P2_MOUSE
CSC1-like protein 2
Tmem63b
218Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YXV7D3YXV7_MOUSE
CSC1-like protein 2
Tmem63b
92Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YYJ8D3YYJ8_MOUSE
CSC1-like protein 2
Tmem63b
200Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH57136 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH59283 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti619Q → R in BAC41131 (PubMed:16141072).Curated1
Sequence conflicti725L → P in AAH26370 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK090200 mRNA Translation: BAC41131.1
AK159673 mRNA Translation: BAE35277.1
BC026370 mRNA Translation: AAH26370.1
BC057136 mRNA Translation: AAH57136.1 Different initiation.
BC059283 mRNA Translation: AAH59283.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS28814.1

NCBI Reference Sequences

More...RefSeqi		NP_937810.2, NM_198167.3
XP_006524199.1, XM_006524136.1
XP_006524200.1, XM_006524137.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000113523; ENSMUSP00000109151; ENSMUSG00000036026

Database of genes from NCBI RefSeq genomes

More...GeneIDi		224807

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:224807

UCSC genome browser

More...UCSCi		uc012auh.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK090200 mRNA Translation: BAC41131.1
AK159673 mRNA Translation: BAE35277.1
BC026370 mRNA Translation: AAH26370.1
BC057136 mRNA Translation: AAH57136.1 Different initiation.
BC059283 mRNA Translation: AAH59283.1 Different initiation.
CCDSiCCDS28814.1
RefSeqiNP_937810.2, NM_198167.3
XP_006524199.1, XM_006524136.1
XP_006524200.1, XM_006524137.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi230322, 3 interactors
IntActiQ3TWI9, 1 interactor
STRINGi10090.ENSMUSP00000109151

PTM databases

iPTMnetiQ3TWI9
PhosphoSitePlusiQ3TWI9
SwissPalmiQ3TWI9

Proteomic databases

jPOSTiQ3TWI9
MaxQBiQ3TWI9
PaxDbiQ3TWI9
PeptideAtlasiQ3TWI9
PRIDEiQ3TWI9

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		30591, 35 antibodies

Genome annotation databases

EnsembliENSMUST00000113523; ENSMUSP00000109151; ENSMUSG00000036026
GeneIDi224807
KEGGimmu:224807
UCSCiuc012auh.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		55362
MGIiMGI:2387609, Tmem63b

Phylogenomic databases

eggNOGiKOG1134, Eukaryota
GeneTreeiENSGT00940000157084
HOGENOMiCLU_015647_0_0_1
InParanoidiQ3TWI9
KOiK21989
OMAiWLWVHTI
OrthoDBi395194at2759
PhylomeDBiQ3TWI9
TreeFamiTF324300

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		224807, 1 hit in 19 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Tmem63b, mouse

Protein Ontology

More...PROi		PR:Q3TWI9
RNActiQ3TWI9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000036026, Expressed in retinal neural layer and 278 other tissues
ExpressionAtlasiQ3TWI9, baseline and differential
GenevisibleiQ3TWI9, MM

Family and domain databases

InterProiView protein in InterPro
IPR032880, Csc1_N
IPR027815, PHM7_cyt
IPR003864, RSN1_7TM
PfamiView protein in Pfam
PF14703, PHM7_cyt, 1 hit
PF02714, RSN1_7TM, 1 hit
PF13967, RSN1_TM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCSCL2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3TWI9
Secondary accession number(s): Q6PCL2
, Q6PGA4, Q8C1V5, Q8R0W7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: October 11, 2005
Last modified: August 12, 2020
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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