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Protein
Submitted name:

Ral guanine nucleotide dissociation stimulator

Gene

Ralgds

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGuanine-nucleotide releasing factorPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ral guanine nucleotide dissociation stimulatorImported
Gene namesi
Name:RalgdsImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:107485 Ralgds

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSMUSG00000026821

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 249N-terminal Ras-GEFInterPro annotationAdd BLAST138
Domaini379 – 641Ras-GEFInterPro annotationAdd BLAST263
Domaini791 – 878Ras-associatingInterPro annotationAdd BLAST88

Phylogenomic databases

eggNOGiKOG3629 Eukaryota
ENOG410ZUT5 LUCA
GeneTreeiENSGT00910000143985
HOGENOMiHOG000231592
HOVERGENiHBG005864
OMAiCKVRTIK
OrthoDBiEOG091G0761
TreeFamiTF315204

Family and domain databases

CDDicd00155 RasGEF, 1 hit
cd06224 REM, 1 hit
Gene3Di1.10.840.10, 1 hit
InterProiView protein in InterPro
IPR000159 RA_dom
IPR015758 RalGDS
IPR000651 Ras-like_Gua-exchang_fac_N
IPR019804 Ras_G-nucl-exch_fac_CS
IPR023578 Ras_GEF_dom_sf
IPR001895 RASGEF_cat_dom
IPR036964 RASGEF_cat_dom_sf
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR23113:SF35 PTHR23113:SF35, 1 hit
PfamiView protein in Pfam
PF00788 RA, 1 hit
PF00617 RasGEF, 1 hit
PF00618 RasGEF_N, 1 hit
SMARTiView protein in SMART
SM00314 RA, 1 hit
SM00147 RasGEF, 1 hit
SM00229 RasGEFN, 1 hit
SUPFAMiSSF48366 SSF48366, 2 hits
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50200 RA, 1 hit
PS00720 RASGEF, 1 hit
PS50009 RASGEF_CAT, 1 hit
PS50212 RASGEF_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q3TWC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQRMWAEAA GPIGGTEPLF PGSRRSRSVW DAVRLEVGVP DSCPVVLHSF
60 70 80 90 100
TQLDPDLPRL ESSTQEIGEE LINGVIYSIS LRKVQLHQGA TKGQRWLGCE
110 120 130 140 150
NESALNLYET CKVRTVKAGT LEKLVEHLVP AFQGSDLSYV TVFLCTYRAF
160 170 180 190 200
TTTQQVLDLL FKRYGRCDAL TASSRYGCIL PYSSEDGGPQ DQLKNAISSI
210 220 230 240 250
LGTWLDQYSE DFCQPPDFPC LKQLVAYVQL NMPGSDLERR AHLLLAQLED
260 270 280 290 300
LEPSEAESEA LSPAPVLSLK PASQLEPALL LTPSQVVTST PVREPAAAPV
310 320 330 340 350
PVLASSPVVA PAPELEPVPE PPQEPEPSLA LAPELEPAVS QSLELESAPV
360 370 380 390 400
PTPALEPSWS LPEATENGLT EKPHLLLFPP DLVAEQFTLM DAELFKKVVP
410 420 430 440 450
YHCLGSIWSQ RDKKGKEHLA PTIRATVAQF NNVANCVITT CLGDQSMKAP
460 470 480 490 500
DRARVVEHWI EVARECRALK NFSSLYAILS ALQSNAIHRL KKTWEEVSRD
510 520 530 540 550
SFRVFQKLSE IFSDENNYSL SRELLIKEGT SKFATLEMNP RRAQRRQKET
560 570 580 590 600
GVIQGTVPYL GTFLTDLVML DTAMKDYLYG RLINFEKRRK EFEVIAQIKL
610 620 630 640 650
LQSACNNYSI APEEHFGTWF RAMERLSEAE SYTLSCELEP PSESASNTLR
660 670 680 690 700
SKKSTAIVKR WSDRQAPSTE LSTSSSAHSK SCDQLRCSPY LGSGDITDAL
710 720 730 740 750
SVHSAGSSSS DVEEINMSFV PESPDGQEKK FWESASQSSP ETSGISSASS
760 770 780 790 800
STSSSSASTT PVSTTRTHKR SVSGVCSYSS SLPLYNQQVG DCCIIRVSLD
810 820 830 840 850
VDNGNMYKSI LVTSQDKAPT VIRKAMDKHN LDEDEPEDYE LVQIISEDHK
860 870 880 890 900
LKIPENANVF YAMNSTANYD FILKKRTFTK GAKVKHGASS TLPRMKQKGL

RIAKGIF
Length:907
Mass (Da):100,207
Last modified:October 11, 2005 - v1
Checksum:i2CD533100ADCEF2B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL772249 Genomic DNA No translation available.
AK159754 mRNA Translation: BAE35345.1
RefSeqiNP_001139307.1, NM_001145835.1
UniGeneiMm.5236

Genome annotation databases

EnsembliENSMUST00000100241; ENSMUSP00000097812; ENSMUSG00000026821
GeneIDi19730
UCSCiuc008iyo.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ3TWC1_MOUSE
AccessioniPrimary (citable) accession number: Q3TWC1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 18, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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