UniProtKB - Q3TPM5 (Q3TPM5_MOUSE)
Protein
Protein kinase domain-containing protein
Gene
Insr
Organism
Mus musculus (Mouse)
Status
Functioni
Catalytic activityi
- EC:2.7.10.1ARBA annotation
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- transmembrane receptor protein tyrosine kinase activity Source: UniProtKB-EC
GO - Biological processi
- transmembrane receptor protein tyrosine kinase signaling pathway Source: InterPro
Names & Taxonomyi
Protein namesi | Recommended name: Protein kinase domain-containing proteinInterPro annotation |
Gene namesi | Name:InsrImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:96575, Insr |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 116 | Protein kinaseInterPro annotationAdd BLAST | 116 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 177 – 200 | DisorderedSequence analysisAdd BLAST | 24 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR020635, Tyr_kinase_cat_dom IPR002011, Tyr_kinase_rcpt_2_CS |
Pfami | View protein in Pfam PF07714, PK_Tyr_Ser-Thr, 1 hit |
PRINTSi | PR00109, TYRKINASE |
SMARTi | View protein in SMART SM00219, TyrKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00239, RECEPTOR_TYR_KIN_II, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q3TPM5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
DIYETDYYRK GGKGLLPVRW MSPESLKDGV FTASSDMWSF GVVLWEITSL
60 70 80 90 100
AEQPYQGLSN EQVLKFVMDG GYLDPPDNCP ERLTDLMRMC WQFNPKMRPT
110 120 130 140 150
FLEIVNLLKD DLHPSFPEVS FFYSEENKAP ESEELEMEFE DMENVPLDRS
160 170 180 190 200
SHCQREEAGG REGGSSLSIK RTYDEHIPYT HMNGGKKNGR VLTLPRSNPS
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK164267 mRNA Translation: BAE37711.1 |
RefSeqi | NP_034698.2, NM_010568.3 |
Genome annotation databases
GeneIDi | 16337 |
KEGGi | mmu:16337 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK164267 mRNA Translation: BAE37711.1 |
RefSeqi | NP_034698.2, NM_010568.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q3TPM5 |
Protocols and materials databases
DNASUi | 16337 |
Genome annotation databases
GeneIDi | 16337 |
KEGGi | mmu:16337 |
Organism-specific databases
CTDi | 3643 |
MGIi | MGI:96575, Insr |
Miscellaneous databases
BioGRID-ORCSi | 16337, 0 hits in 52 CRISPR screens |
ChiTaRSi | Insr, mouse |
SOURCEi | Search... |
Gene expression databases
Genevisiblei | Q3TPM5, MM |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR020635, Tyr_kinase_cat_dom IPR002011, Tyr_kinase_rcpt_2_CS |
Pfami | View protein in Pfam PF07714, PK_Tyr_Ser-Thr, 1 hit |
PRINTSi | PR00109, TYRKINASE |
SMARTi | View protein in SMART SM00219, TyrKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00239, RECEPTOR_TYR_KIN_II, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3TPM5_MOUSE | |
Accessioni | Q3TPM5Primary (citable) accession number: Q3TPM5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | April 7, 2021 | |
This is version 115 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |