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Protein
Submitted name:

A disintegrin and metalloproteinase with thrombospondin motifs 4

Gene

Adamts4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
A disintegrin and metalloproteinase with thrombospondin motifs 4Imported
Gene namesi
Name:Adamts4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1339949 Adamts4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000006403

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini226 – 436Peptidase M12BInterPro annotationAdd BLAST211

Phylogenomic databases

eggNOGiKOG3538 Eukaryota
ENOG410XPKZ LUCA
GeneTreeiENSGT00900000140774
HOGENOMiHOG000004799
HOVERGENiHBG004313
OMAiKFRYGYN
OrthoDBiEOG091G00AX
TreeFamiTF331949

Family and domain databases

Gene3Di2.20.100.10, 1 hit
3.40.390.10, 1 hit
InterProiView protein in InterPro
IPR006586 ADAM_Cys-rich
IPR010294 ADAM_spacer1
IPR024079 MetalloPept_cat_dom_sf
IPR001590 Peptidase_M12B
IPR002870 Peptidase_M12B_N
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf
PfamiView protein in Pfam
PF05986 ADAM_spacer1, 1 hit
PF01562 Pep_M12B_propep, 1 hit
PF01421 Reprolysin, 1 hit
PF00090 TSP_1, 1 hit
SMARTiView protein in SMART
SM00608 ACR, 1 hit
SM00209 TSP1, 1 hit
SUPFAMiSSF82895 SSF82895, 1 hit
PROSITEiView protein in PROSITE
PS50215 ADAM_MEPRO, 1 hit
PS50092 TSP1, 1 hit

Sequencei

Sequence statusi: Complete.

Q3TNX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASIHPSCSP GTMSQMGLHP RRGLTGHWLQ RFQPCLPLHT VQWRRLLLLA
60 70 80 90 100
FLLSLAWPAS PLPREEEIVF PEKLNGSSIL PGSGVPARLL YRLPAFGEML
110 120 130 140 150
LLELEQDPGV QVEGLTVQYL GQAPEMLGGA EPGTYLTGTI NGDPESVASL
160 170 180 190 200
HWDGGALLGV LQYRGAELHL QPLEGGALNS AGGPGAHILR RKSPASSQGP
210 220 230 240 250
MCTVKAPSGS PSPISRRTKR FASLSRFVET LVVADDKMAA FHGTGLKRYL
260 270 280 290 300
LTVMAAAAKA FKHPSIRNPV NLVVTRLVIL GSGQEGPQVG PSAAQTLRSF
310 320 330 340 350
CTWQRGLNTP NDSDPDHFDT AILFTRQDLC GVSTCDTLGM ADVGTVCDPA
360 370 380 390 400
RSCAIVEDDG LQSAFTAAHE LGHVFNMLHD NSKPCTNLNG QGGSSRHVMA
410 420 430 440 450
PVMAHVDPEE PWSPCSARFI TDFLDNGYGH CLLDKPEAPL HLPATFPGKD
460 470 480 490 500
YDADRQCQLT FGPDSSHCPQ LPPPCAALWC SGHLNGHAMC QTKHSPWADG
510 520 530 540 550
TPCGSSQACM GGRCLHVDQL KDFNVPQAGG WGPWGPWGDC SRTCGGGVQF
560 570 580 590 600
SSRDCTRPVP RNGGKYCEGR RTRFRSCNTE NCPHGSALTF REEQCAAYNH
610 620 630 640 650
RTDLFKSFPG PMDWVPRYTG VAPRDQCKLT CQARALGYYY VLEPRVADGT
660 670 680 690 700
PCSPDTSSVC VQGRCIHAGC DRIIGSKKKF DKCMVCGGDG SRCSKQSGSF
710 720 730 740 750
KKFRYGYSDV VTIPAGATHI LVRQQGGSGL KSIYLALKLS DGSYALNGEY
760 770 780 790 800
TLMPSPTDVV LPGAVSLRYS GATAASETLS GHGPLAQPLT LQVLVAGNPQ
810 820 830 840
NARLRYSFFV PRPVPSTPRP PPQDWLQRRA EILKILRKRP WAGRK
Length:845
Mass (Da):91,239
Last modified:October 11, 2005 - v1
Checksum:iB496C3190D1A9225
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084821 Genomic DNA No translation available.
AK164900 mRNA Translation: BAE37959.1
UniGeneiMm.491147

Genome annotation databases

EnsembliENSMUST00000219033; ENSMUSP00000151387; ENSMUSG00000006403
UCSCiuc007dnn.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ3TNX8_MOUSE
AccessioniPrimary (citable) accession number: Q3TNX8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 18, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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