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Entry version 131 (07 Oct 2020)
Sequence version 1 (11 Oct 2005)
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Protein

MICAL-like protein 2

Gene

Micall2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth.5 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MICAL-like protein 2
Alternative name(s):
Junctional Rab13-binding protein
Molecule interacting with CasL-like 2
Short name:
MICAL-L2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Micall2
Synonyms:Jrab
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444818, Micall2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Endosome, Membrane, Tight junction

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004242271 – 1009MICAL-like protein 2Add BLAST1009

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei110PhosphoserineBy similarity1
Modified residuei143PhosphoserineBy similarity1
Modified residuei153PhosphoserineBy similarity1
Modified residuei249PhosphoserineBy similarity1
Modified residuei766PhosphoserineCombined sources1
Modified residuei768PhosphoserineBy similarity1
Modified residuei832PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q3TN34

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q3TN34

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3TN34

PeptideAtlas

More...
PeptideAtlasi
Q3TN34

PRoteomics IDEntifications database

More...
PRIDEi
Q3TN34

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q3TN34

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3TN34

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in brain, lung, liver and kidney (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000036718, Expressed in intestine and 185 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q3TN34, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RAB13 (GTP-bound form); competes with RAB8A and is involved in tight junctions assembly.

Interacts with RAB8A; competes with RAB13 and is involved in E-cadherin endocytic recycling.

Interacts with RAB8B.

Interacts (preferentially in opened conformation) with ACTN1 and ACTN4; stimulated by RAB13 activation.

Interacts (via calponin-homology (CH) domain) with the filamins FLNA, FLNB and FLNC (via actin-binding domain).

6 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
231173, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q3TN34, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000039707

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q3TN34, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q3TN34

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 107Calponin-homology (CH)PROSITE-ProRule annotationAdd BLAST107
Domaini186 – 248LIM zinc-bindingPROSITE-ProRule annotationAdd BLAST63
Domaini833 – 980bMERBPROSITE-ProRule annotationAdd BLAST148

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 260Forms an intramolecular interaction with the C-terminal coiled coil domain keeping the protein in a closed conformationAdd BLAST260
Regioni261 – 805Mediates targeting to the cell plasma membraneAdd BLAST545
Regioni261 – 393Necessary and sufficient for interaction with actininsAdd BLAST133
Regioni806 – 913Forms an intramolecular interaction with the N-terminal Calponin-homology and LIM zinc-binding domains-containing region keeping the protein in a closed conformationAdd BLAST108
Regioni913 – 1009Mediates interaction with RAB13 and is required for transition from the closed to the open conformationAdd BLAST97

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili841 – 880Sequence analysisAdd BLAST40

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Probably exists in a closed and an open conformation due to interaction of the C-terminal coiled-coil domain with an N-terminal region including the calponin-homology (CH) and the LIM zinc-binding domain. The conformational change is regulated by RAB13.3 Publications

Keywords - Domaini

Coiled coil, LIM domain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QVVF, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160222

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015382_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3TN34

KEGG Orthology (KO)

More...
KOi
K21068

Database of Orthologous Groups

More...
OrthoDBi
377701at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q3TN34

TreeFam database of animal gene trees

More...
TreeFami
TF328311

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014, CH, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022735, bMERB_dom
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR028563, MICAL-L
IPR001781, Znf_LIM

The PANTHER Classification System

More...
PANTHERi
PTHR23167:SF53, PTHR23167:SF53, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307, CH, 1 hit
PF12130, DUF3585, 1 hit
PF00412, LIM, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033, CH, 1 hit
SM00132, LIM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51848, BMERB, 1 hit
PS50021, CH, 1 hit
PS00478, LIM_DOMAIN_1, 1 hit
PS50023, LIM_DOMAIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q3TN34-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAIKALQEW CRQQCEGYRD VSITNMTTSF RDGLAFCAIL HRHRPDLINF
60 70 80 90 100
SALRKENIYE NNKLAFQVAE EQLGIPALLD AEDMVALKVP DRLSILTYVS
110 120 130 140 150
QYYNYFHGRS PIGGMAGIKR PSSDSTEELS GKKGLSQPAK LPSPAQTQRS
160 170 180 190 200
PLSPARTNPV VQRNEGGSQR PSPKAAPGTA GSSVSSICGV CGKHVHLVQR
210 220 230 240 250
HLADGRLYHR SCFRCKQCSS TLHSGAYRAT GEPGVFVCTH HSSEVTSVSP
260 270 280 290 300
KSSNLASRKP GGVTADTRPF GVSWTVQEAN GEGTPLRVRT AAWEHAGGNT
310 320 330 340 350
TAKGFVQTEL KPPSTSQVHV GSSAGPKLPT ITVTTTSVTS KALTHVTNSS
360 370 380 390 400
PIGWSSPAQS SPANFNSRPV VSPSARNTHL PGSQGQTASK GVKTQLNLNS
410 420 430 440 450
ESSNTAVTPA WTSSASKTQQ AREKFFQTPP SAPAPASAPA PAPTSKVPTV
460 470 480 490 500
VTVPTSKVPN VVTAPTSKVP TVVTVPTSKV PTVVSAPTSK VPTVVSAPTS
510 520 530 540 550
KVPTVVNSTN SRVTTVVNAP TSKVPTVVSA TNGRVPTVVT AHTGRVPAVM
560 570 580 590 600
NTSASKVSPV VDAPAQESSR EQALSVLRKA LPALTGSGTQ APNRSFPATS
610 620 630 640 650
SVLVTLPKNE VPQKVPSDKL SALTTQTPNF TIKLEPSAPV NVGNTAVFLQ
660 670 680 690 700
AGKKSPSISP RVGKTSVGSR PQAEVAGVKG PGPISQEGQE EGPEGWRARL
710 720 730 740 750
KPVDKKTPAG RSLEQKEPVL AEPRIGDTSR KASSSSDSSV HITLTSIQHK
760 770 780 790 800
RKPCPAGSGP SPAALSPSPS HRKKLAVPPS LDVSADWLQP EPKKQEDGTR
810 820 830 840 850
SCKEEKSPTR WSRERSAVLD SGLAPPGEAV TSPVRLHPDY IPQEELQRQL
860 870 880 890 900
QDIESQLDAL ELRGVELEKR LRAAEGDASE DSLMVDWFRL IHEKQLLLRL
910 920 930 940 950
ESELMYKSKD QRLEEQQLDL QGELRRLMDK PEGLKSPQDR QREQELLSQY
960 970 980 990 1000
VNTVNDRSDI VDFLDEDRLR EQEEDQMLEN MIQNLGLQRK KSKSFLSKIW

SSKSKSGQA
Length:1,009
Mass (Da):108,288
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3D059CD22B8BAF53
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PZD2E9PZD2_MOUSE
MICAL-like protein 2
Micall2
926Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6UYB3F6UYB3_MOUSE
MICAL-like protein 2
Micall2
23Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti770S → L in BAE37602 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB182579 mRNA Translation: BAE86912.1
AK151086 mRNA Translation: BAE30099.1
AK164043 mRNA Translation: BAE37602.1
AK165558 mRNA Translation: BAE38255.1
AC167333 Genomic DNA No translation available.
CH466529 Genomic DNA Translation: EDL19139.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS39353.2

NCBI Reference Sequences

More...
RefSeqi
NP_777275.2, NM_174850.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000044642; ENSMUSP00000039707; ENSMUSG00000036718

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
231830

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:231830

UCSC genome browser

More...
UCSCi
uc009agx.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB182579 mRNA Translation: BAE86912.1
AK151086 mRNA Translation: BAE30099.1
AK164043 mRNA Translation: BAE37602.1
AK165558 mRNA Translation: BAE38255.1
AC167333 Genomic DNA No translation available.
CH466529 Genomic DNA Translation: EDL19139.1
CCDSiCCDS39353.2
RefSeqiNP_777275.2, NM_174850.3

3D structure databases

SMRiQ3TN34
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi231173, 3 interactors
IntActiQ3TN34, 3 interactors
STRINGi10090.ENSMUSP00000039707

PTM databases

iPTMnetiQ3TN34
PhosphoSitePlusiQ3TN34

Proteomic databases

jPOSTiQ3TN34
MaxQBiQ3TN34
PaxDbiQ3TN34
PeptideAtlasiQ3TN34
PRIDEiQ3TN34

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
24191, 80 antibodies

Genome annotation databases

EnsembliENSMUST00000044642; ENSMUSP00000039707; ENSMUSG00000036718
GeneIDi231830
KEGGimmu:231830
UCSCiuc009agx.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79778
MGIiMGI:2444818, Micall2

Phylogenomic databases

eggNOGiENOG502QVVF, Eukaryota
GeneTreeiENSGT00940000160222
HOGENOMiCLU_015382_0_0_1
InParanoidiQ3TN34
KOiK21068
OrthoDBi377701at2759
PhylomeDBiQ3TN34
TreeFamiTF328311

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
231830, 0 hits in 18 CRISPR screens

Protein Ontology

More...
PROi
PR:Q3TN34
RNActiQ3TN34, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000036718, Expressed in intestine and 185 other tissues
GenevisibleiQ3TN34, MM

Family and domain databases

CDDicd00014, CH, 1 hit
Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR022735, bMERB_dom
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR028563, MICAL-L
IPR001781, Znf_LIM
PANTHERiPTHR23167:SF53, PTHR23167:SF53, 2 hits
PfamiView protein in Pfam
PF00307, CH, 1 hit
PF12130, DUF3585, 1 hit
PF00412, LIM, 1 hit
SMARTiView protein in SMART
SM00033, CH, 1 hit
SM00132, LIM, 1 hit
SUPFAMiSSF47576, SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS51848, BMERB, 1 hit
PS50021, CH, 1 hit
PS00478, LIM_DOMAIN_1, 1 hit
PS50023, LIM_DOMAIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMILK2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3TN34
Secondary accession number(s): Q3TPY3, Q3UB65
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 16, 2013
Last sequence update: October 11, 2005
Last modified: October 7, 2020
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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