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Protein

Trafficking protein particle complex subunit 10

Gene

Trappc10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in vesicular transport from endoplasmic reticulum to Golgi.By similarity

GO - Biological processi

Keywordsi

Biological processER-Golgi transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Trafficking protein particle complex subunit 10
Alternative name(s):
Trafficking protein particle complex subunit TMEM1
Transport protein particle subunit TMEM1
Short name:
TRAPP subunit TMEM1
Gene namesi
Name:Trappc10
Synonyms:Tmem1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1336209 Trappc10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003314801 – 1259Trafficking protein particle complex subunit 10Add BLAST1259

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei708PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ3TLI0
MaxQBiQ3TLI0
PaxDbiQ3TLI0
PRIDEiQ3TLI0

PTM databases

iPTMnetiQ3TLI0
PhosphoSitePlusiQ3TLI0

Interactioni

Subunit structurei

Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12.By similarity

Protein-protein interaction databases

IntActiQ3TLI0, 1 interactor
STRINGi10090.ENSMUSP00000000384

Structurei

3D structure databases

ProteinModelPortaliQ3TLI0
SMRiQ3TLI0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi1019 – 1022Poly-Pro4

Sequence similaritiesi

Belongs to the TMEM1 family.Curated

Phylogenomic databases

eggNOGiKOG1931 Eukaryota
ENOG410XNVF LUCA
HOGENOMiHOG000046007
HOVERGENiHBG108593
InParanoidiQ3TLI0
PhylomeDBiQ3TLI0

Family and domain databases

InterProiView protein in InterPro
IPR022233 TRAPP_II_complex_TRAPPC10
PfamiView protein in Pfam
PF12584 TRAPPC10, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q3TLI0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAPEEPQPP VVYTMENKPI VTCAGDQNLF TSIYPTLSQQ LPREPMEWRR
60 70 80 90 100
SYGRAPKMIH LESNFVQFKE ELLPKEGNKA LLTFPFLHIY WTECCDTEVY
110 120 130 140 150
KATVKDDLTK WQNVLKAHSS VDWLIVVVEN DAKKKNKTNI LPRTSIVDKI
160 170 180 190 200
RNDFCNKQSD RCVVLSDPLK DSSRTQESWN AFLTKLRTLL LMSFTKNLGK
210 220 230 240 250
FEDDMRTLRE KRTEPGWSFC EYFMVQEELA FVFEMLQQFE DALVQYDELD
260 270 280 290 300
ALFSQYVVNF GAGDGANWLT FFCQPVKSWN GLVLRKPIDM EKRELIQKQE
310 320 330 340 350
ATLLDLRSYL FSRQCTLLLF LQRPWEVAQR ALELLHSCVQ ELKLLEVSVP
360 370 380 390 400
PGALDCWVFL SCLEVLQRIE GCCDRAQIDS NIAHMVGLWS YAMEKLKSLG
410 420 430 440 450
YLCGLVSEKG PNSEDLNRTV DLLAGLGAER PETANTAQSP YKKLQEALSS
460 470 480 490 500
VEAFEKHYLD LSHATIEMYT SIGRIRSAKL VGKDLAEFYM RKRSPQKAEM
510 520 530 540 550
YLQGALKNYL AEGWALPVTH TRKQLAECQK HLGQMENYLQ TSSLLASDHH
560 570 580 590 600
LTEEERKYFC QEILSFASQQ EDNPGHKVVL PMHSFARLKD LHFDPPNAVV
610 620 630 640 650
HAGGVLTVEI TVCSQMPIPV HVDQIAVNVH FSIEKNNYRK TAEWLTKHKT
660 670 680 690 700
SNGIITFPAE ASLFPASQNS LPALELSEML ERSPSDNSLN TTGIICRNVH
710 720 730 740 750
MLLRRQESGS SLEPPSGLAL EDGAHVLRCS SVTLQPGANK IAFKTQAKEP
760 770 780 790 800
GTYTLRQLRA SVGPVWFVLA HIHPIVQYDV YSQEPQLHVE PLADSLLAGI
810 820 830 840 850
PQKVKFTVTT GHYTVKNGDS LQLSNVEAML ILCQAENRAV VYSNSREECS
860 870 880 890 900
TALLRIQSSD KVTSIGLPTA PAYHVIEFEL EVLSLPSAPA SGGDTSVPGT
910 920 930 940 950
PELHRKQKDS QRAGHCMVTT DHKVSIDCPW SIYSTVIALT FSVPFRTEHS
960 970 980 990 1000
LLSAGTRKYV QVCVQNLSEL DFELSDSNLE DKGHATDLRL APLNTQSQQL
1010 1020 1030 1040 1050
IHSKQSVFFV WELTWTQEPP PPLHCQFSVG FSPASEEQLT VSLKPYTYEF
1060 1070 1080 1090 1100
QVENFFTLYS VRAEILPASG AEYCKTGSLC SLEVSITRLA DLLDVDKDEA
1110 1120 1130 1140 1150
LVESEDYFST KLMYEVVDNS SNWAVCGKSC GVIAMPLAAQ ATHRVHMEVM
1160 1170 1180 1190 1200
PLFAGYLPLP DVRLFKYLPH HSAHASQLDA DSWIENDSLS VDKHLDDQLD
1210 1220 1230 1240 1250
CSSLRSRGST HSTSSSEHKG LPMPRLQALP AGQVFNSSTG MQVLVIPSQD

DHVLEVSVT
Length:1,259
Mass (Da):141,589
Last modified:April 29, 2008 - v2
Checksum:iC1176D7154B76A3D
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8VQF9F8VQF9_MOUSE
Trafficking protein particle comple...
Trappc10
1,258Annotation score:
A0A1W2P8E9A0A1W2P8E9_MOUSE
Trafficking protein particle comple...
Trappc10
181Annotation score:
A0A1W2P717A0A1W2P717_MOUSE
Trafficking protein particle comple...
Trappc10
100Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti683S → N in AAH44902 (PubMed:15489334).Curated1
Sequence conflicti1047T → I in AAH44902 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK166500 mRNA Translation: BAE38812.1
BC044902 mRNA Translation: AAH44902.1
UniGeneiMm.27539
Mm.338989

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK166500 mRNA Translation: BAE38812.1
BC044902 mRNA Translation: AAH44902.1
UniGeneiMm.27539
Mm.338989

3D structure databases

ProteinModelPortaliQ3TLI0
SMRiQ3TLI0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ3TLI0, 1 interactor
STRINGi10090.ENSMUSP00000000384

PTM databases

iPTMnetiQ3TLI0
PhosphoSitePlusiQ3TLI0

Proteomic databases

EPDiQ3TLI0
MaxQBiQ3TLI0
PaxDbiQ3TLI0
PRIDEiQ3TLI0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1336209 Trappc10

Phylogenomic databases

eggNOGiKOG1931 Eukaryota
ENOG410XNVF LUCA
HOGENOMiHOG000046007
HOVERGENiHBG108593
InParanoidiQ3TLI0
PhylomeDBiQ3TLI0

Miscellaneous databases

PROiPR:Q3TLI0
SOURCEiSearch...

Family and domain databases

InterProiView protein in InterPro
IPR022233 TRAPP_II_complex_TRAPPC10
PfamiView protein in Pfam
PF12584 TRAPPC10, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTPC10_MOUSE
AccessioniPrimary (citable) accession number: Q3TLI0
Secondary accession number(s): Q811H4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: November 7, 2018
This is version 78 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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