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Entry version 91 (12 Aug 2020)
Sequence version 1 (11 Oct 2005)
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Protein
Submitted name:

Uncharacterized protein

Gene

Zc3h7a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri633 – 655C3H1-typePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri768 – 796C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri905 – 927C3H1-typePROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zc3h7aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2445044, Zc3h7a

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini633 – 655C3H1-typeInterPro annotationAdd BLAST23
Domaini768 – 796C3H1-typeInterPro annotationAdd BLAST29
Domaini905 – 927C3H1-typeInterPro annotationAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili929 – 949Sequence analysisAdd BLAST21

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri633 – 655C3H1-typePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri768 – 796C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri905 – 927C3H1-typePROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat
IPR039691, ZC3H7A/B
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
IPR000571, Znf_CCCH
IPR036855, Znf_CCCH_sf

The PANTHER Classification System

More...
PANTHERi
PTHR14928, PTHR14928, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028, TPR, 2 hits
SM00356, ZnF_C3H1, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452, SSF48452, 1 hit
SSF57667, SSF57667, 1 hit
SSF90229, SSF90229, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50103, ZF_C3H1, 3 hits
PS00028, ZINC_FINGER_C2H2_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q3TIQ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSVSEERRK RQHSIKEGLQ FIQSPLSYPG TQEQYAVYLH ALVRNLFNEG
60 70 80 90 100
NDIYRECDWR GSLIQYSEAL SIANYAKSEE ILIPTEIIEK LRINRIACYS
110 120 130 140 150
NMGLRDEVLE DCNAVLSVNA SNCKALYRKA KALSDLGHYR EAYDAVAKCS
160 170 180 190 200
LAVPQDEHVI KLTQELAQKL GFKIRKAYVR AEHLLKAVPG DGAPKAVNYS
210 220 230 240 250
VEDIEPDLLA QRQEALSVAS LPTSSFSHVI GSELASVPIM PVTSVLQLQV
260 270 280 290 300
DESPLPSTVF ANGGKIPFTI SDAFLDDDIV LGDEIDALLD SAPETNDAVM
310 320 330 340 350
SSTLVRGPLP TASAAPSLPF RTQSLLGTLP MGTRYPEPSF ADFFPPLTSS
360 370 380 390 400
LEEFYSSLNS FSVTESKRDL CTSTAREGTP LNNSNSSLLL MNGRGNLLAS
410 420 430 440 450
ENFLGITSQP RNDFGNFFGS VIAKPFSSGT PRHPLEGTHE LRQACQICFV
460 470 480 490 500
KSGPKLMDFT YHANVDHKCK KDILIGRIKN VEDKSWKKIR PRPTKTNYEG
510 520 530 540 550
PYYICKDVAA DDECRYPGHC TFAYCQEEID VWTLERKGAF SREAFFGGNG
560 570 580 590 600
KINLTVVRIL QEHHGEFTFL CEKCFDHKPR MISKRNKDNS TACSHPVTKH
610 620 630 640 650
EFEDNKCLVH ILRETTVKYS KIRSFHKQCQ FDICRHEVRY GCVREDECFY
660 670 680 690 700
AHSLIELKVW IMQSERGISH DDIAQQSKQY WRSLQASMPG VQVLGNQIMP
710 720 730 740 750
GLLNMEIKFV CAQCLRNGQV IEPDRNRKYC SAKAQHSWTK ERRAMRAMSF
760 770 780 790 800
ERKKWMNIRP LPTKKQMPLQ FDLCNHIANR KKCQYVGNCS FAHSPEEREV
810 820 830 840 850
WTYMKDNKIH DIEQFYELWL KNQKTEKSDE TASHCSKENG KQIHMPTDYA
860 870 880 890 900
EVTVDFHCWM CGKNCNSEKQ WQDHISSEKH KEKVFHTEDD QYCWQHRFPT
910 920 930 940 950
GYFSICERYI NGSCTEGSSC KFAHGNAELH EWEERRKALQ MKFKKARKDH
960 970
LIAPNDNDFG KYSFLFKDLK
Length:970
Mass (Da):110,883
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i50240CFAC99E47F7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK167758 mRNA Translation: BAE39792.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK167758 mRNA Translation: BAE39792.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Organism-specific databases

MGIiMGI:2445044, Zc3h7a

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Zc3h7a, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat
IPR039691, ZC3H7A/B
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
IPR000571, Znf_CCCH
IPR036855, Znf_CCCH_sf
PANTHERiPTHR14928, PTHR14928, 1 hit
SMARTiView protein in SMART
SM00028, TPR, 2 hits
SM00356, ZnF_C3H1, 3 hits
SUPFAMiSSF48452, SSF48452, 1 hit
SSF57667, SSF57667, 1 hit
SSF90229, SSF90229, 1 hit
PROSITEiView protein in PROSITE
PS50103, ZF_C3H1, 3 hits
PS00028, ZINC_FINGER_C2H2_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ3TIQ4_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3TIQ4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: August 12, 2020
This is version 91 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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