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Protein
Submitted name:

WD repeat and SOCS box-containing 1, isoform CRA_b

Gene

Wsb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Enzyme and pathway databases

UniPathwayi
UPA00143

Names & Taxonomyi

Protein namesi
Submitted name:
WD repeat and SOCS box-containing 1, isoform CRA_bImported
Gene namesi
Name:Wsb1Imported
ORF Names:mCG_1589Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1926139 Wsb1

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSMUSG00000017677 Expressed in 288 organ(s), highest expression level in pineal body
ExpressionAtlasiQ3TFQ2 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini136 – 388WD_REPEATS_REGIONInterPro annotationAdd BLAST253
Repeati136 – 165WDPROSITE-ProRule annotationAdd BLAST30
Repeati166 – 208WDPROSITE-ProRule annotationAdd BLAST43
Repeati210 – 251WDPROSITE-ProRule annotationAdd BLAST42
Repeati252 – 293WDPROSITE-ProRule annotationAdd BLAST42
Repeati314 – 348WDPROSITE-ProRule annotationAdd BLAST35
Repeati358 – 378WDPROSITE-ProRule annotationAdd BLAST21
Domaini377 – 421SOCS boxInterPro annotationAdd BLAST45

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0266 Eukaryota
ENOG410XP3K LUCA
HOVERGENiHBG034543
KOiK10341
OMAiGHHNDVV
OrthoDBiEOG091G06GY

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF07525 SOCS_box, 1 hit
PF00400 WD40, 5 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00253 SOCS, 1 hit
SM00969 SOCS_box, 1 hit
SM00320 WD40, 6 hits
SUPFAMiSSF158235 SSF158235, 1 hit
SSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50225 SOCS, 1 hit
PS00678 WD_REPEATS_1, 2 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

Q3TFQ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASFPPRVNE KEIVRSRTIG ELLAPAAPFD KKCGGENWTV AFAPDGSYFA
60 70 80 90 100
WSQGYRIVKL VPWSQCRKNF LLHGSKNVTN SSCLKLARQN SNGGQKNKPP
110 120 130 140 150
EHVIDCGDIV WSLAFGSSVP EKQSRCVNIE WHRFRFGQDQ LLLATGLNNG
160 170 180 190 200
RIKIWDVYTG KLLLNLVDHI EMVRDLTFAP DGSLLLVSAS RDKTLRVWDL
210 220 230 240 250
KDDGNMVKVL RAHQNWVYSC AFSPDCSMLC SVGASKAVFL WNMDKYTMIR
260 270 280 290 300
KLEGHHHDVV ACDFSPDGAL LATASYDTRV YVWDPHNGDL LMEFGHLFPS
310 320 330 340 350
PTPIFAGGAN DRWVRAVSFS HDGLHVASLA DDKMVRFWRI DEDCPVQVAP
360 370 380 390 400
LSNGLCCAFS TDGSVLAAGT HDGSVYFWAT PRQVPSLQHI CRMSIRRVMS
410 420
TQEVQKLPVP SKILAFLSYR G
Length:421
Mass (Da):47,065
Last modified:February 5, 2008 - v1
Checksum:i4003D1FFE7A9A2EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK145974 mRNA Translation: BAE26797.1
AK146752 mRNA Translation: BAE27409.1
AK150394 mRNA Translation: BAE29522.1
AK150600 mRNA Translation: BAE29692.1
AK159905 mRNA Translation: BAE35469.1
AK167174 mRNA Translation: BAE39310.1
AK167394 mRNA Translation: BAE39483.1
AK169058 mRNA Translation: BAE40846.1
CH466556 Genomic DNA Translation: EDL15604.1
RefSeqiNP_062627.3, NM_019653.3
UniGeneiMm.307022
Mm.474790

Genome annotation databases

GeneIDi78889
KEGGimmu:78889

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK145974 mRNA Translation: BAE26797.1
AK146752 mRNA Translation: BAE27409.1
AK150394 mRNA Translation: BAE29522.1
AK150600 mRNA Translation: BAE29692.1
AK159905 mRNA Translation: BAE35469.1
AK167174 mRNA Translation: BAE39310.1
AK167394 mRNA Translation: BAE39483.1
AK169058 mRNA Translation: BAE40846.1
CH466556 Genomic DNA Translation: EDL15604.1
RefSeqiNP_062627.3, NM_019653.3
UniGeneiMm.307022
Mm.474790

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi78889
KEGGimmu:78889

Organism-specific databases

CTDi26118
MGIiMGI:1926139 Wsb1

Phylogenomic databases

eggNOGiKOG0266 Eukaryota
ENOG410XP3K LUCA
HOVERGENiHBG034543
KOiK10341
OMAiGHHNDVV
OrthoDBiEOG091G06GY

Enzyme and pathway databases

UniPathwayi
UPA00143

Miscellaneous databases

ChiTaRSiWsb1 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000017677 Expressed in 288 organ(s), highest expression level in pineal body
ExpressionAtlasiQ3TFQ2 baseline and differential

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF07525 SOCS_box, 1 hit
PF00400 WD40, 5 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00253 SOCS, 1 hit
SM00969 SOCS_box, 1 hit
SM00320 WD40, 6 hits
SUPFAMiSSF158235 SSF158235, 1 hit
SSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50225 SOCS, 1 hit
PS00678 WD_REPEATS_1, 2 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ3TFQ2_MOUSE
AccessioniPrimary (citable) accession number: Q3TFQ2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: September 12, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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