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Protein

SPRY domain-containing protein 7

Gene

Spryd7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
SPRY domain-containing protein 7
Alternative name(s):
Chronic lymphocytic leukemia deletion region gene 6 protein homolog
Short name:
CLL deletion region gene 6 protein homolog
Gene namesi
Name:Spryd7
Synonyms:Clld6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1913924 Spryd7

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002439262 – 196SPRY domain-containing protein 7Add BLAST195

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ3TFQ1
MaxQBiQ3TFQ1
PaxDbiQ3TFQ1
PeptideAtlasiQ3TFQ1
PRIDEiQ3TFQ1

PTM databases

PhosphoSitePlusiQ3TFQ1
SwissPalmiQ3TFQ1

Expressioni

Gene expression databases

BgeeiENSMUSG00000021930 Expressed in 279 organ(s), highest expression level in hypothalamus
CleanExiMM_6330409N04RIK
ExpressionAtlasiQ3TFQ1 baseline and differential
GenevisibleiQ3TFQ1 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022497

Structurei

3D structure databases

ProteinModelPortaliQ3TFQ1
SMRiQ3TFQ1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 184B30.2/SPRYPROSITE-ProRule annotationAdd BLAST183

Phylogenomic databases

eggNOGiKOG4030 Eukaryota
ENOG410XNNE LUCA
GeneTreeiENSGT00390000011048
HOVERGENiHBG056533
InParanoidiQ3TFQ1
OMAiDRESWCL
OrthoDBiEOG091G0KM6
PhylomeDBiQ3TFQ1
TreeFamiTF314996

Family and domain databases

CDDicd12880 SPRYD7, 1 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR013320 ConA-like_dom_sf
IPR003877 SPRY_dom
IPR035766 SPRYD7
PANTHERiPTHR20951 PTHR20951, 1 hit
PfamiView protein in Pfam
PF00622 SPRY, 1 hit
SMARTiView protein in SMART
SM00449 SPRY, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q3TFQ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASAWCCLR CCRDGGTGHI PLKEMPAVQL DTQHMGTDVV IVKNGRRICG
60 70 80 90 100
TGGCLASAPL HQNKSYFEFK IQSTGIWGIG VATQKVNLNQ IPLGRDMHSL
110 120 130 140 150
VMRNDGALYH NNEEKNRLPA NSLPQEGDVV GITYDHVELN VYLNGKNMHC
160 170 180 190
PASGIRGTVY PVVYVDDSAI LDCQFSEFYH TPPPGFEKIL FEQQIF
Length:196
Mass (Da):21,681
Last modified:June 27, 2006 - v2
Checksum:i238C69FC296A4C57
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3UBW1Q3UBW1_MOUSE
SPRY domain-containing protein 7
Spryd7 6330409N04Rik
163Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti7C → S in BAB31148 (PubMed:16141072).Curated1
Sequence conflicti174Q → E in BAB31049 (PubMed:16141072).Curated1
Sequence conflicti179Y → H in BAB31148 (PubMed:16141072).Curated1
Sequence conflicti186F → V in BAB31049 (PubMed:16141072).Curated1
Sequence conflicti194Q → R in BAE40847 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018044 mRNA Translation: BAB31049.1
AK018153 mRNA Translation: BAB31097.2
AK018290 mRNA Translation: BAB31148.1
AK137685 mRNA Translation: BAE23460.1
AK167306 mRNA Translation: BAE39410.1
AK169059 mRNA Translation: BAE40847.1
BC037015 mRNA Translation: AAH37015.1
CCDSiCCDS27185.1
RefSeqiNP_001297532.1, NM_001310603.1
NP_079973.1, NM_025697.4
UniGeneiMm.282706

Genome annotation databases

EnsembliENSMUST00000022497; ENSMUSP00000022497; ENSMUSG00000021930
GeneIDi66674
KEGGimmu:66674
UCSCiuc007ufx.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018044 mRNA Translation: BAB31049.1
AK018153 mRNA Translation: BAB31097.2
AK018290 mRNA Translation: BAB31148.1
AK137685 mRNA Translation: BAE23460.1
AK167306 mRNA Translation: BAE39410.1
AK169059 mRNA Translation: BAE40847.1
BC037015 mRNA Translation: AAH37015.1
CCDSiCCDS27185.1
RefSeqiNP_001297532.1, NM_001310603.1
NP_079973.1, NM_025697.4
UniGeneiMm.282706

3D structure databases

ProteinModelPortaliQ3TFQ1
SMRiQ3TFQ1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022497

PTM databases

PhosphoSitePlusiQ3TFQ1
SwissPalmiQ3TFQ1

Proteomic databases

EPDiQ3TFQ1
MaxQBiQ3TFQ1
PaxDbiQ3TFQ1
PeptideAtlasiQ3TFQ1
PRIDEiQ3TFQ1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000022497; ENSMUSP00000022497; ENSMUSG00000021930
GeneIDi66674
KEGGimmu:66674
UCSCiuc007ufx.1 mouse

Organism-specific databases

CTDi57213
MGIiMGI:1913924 Spryd7

Phylogenomic databases

eggNOGiKOG4030 Eukaryota
ENOG410XNNE LUCA
GeneTreeiENSGT00390000011048
HOVERGENiHBG056533
InParanoidiQ3TFQ1
OMAiDRESWCL
OrthoDBiEOG091G0KM6
PhylomeDBiQ3TFQ1
TreeFamiTF314996

Miscellaneous databases

PROiPR:Q3TFQ1
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021930 Expressed in 279 organ(s), highest expression level in hypothalamus
CleanExiMM_6330409N04RIK
ExpressionAtlasiQ3TFQ1 baseline and differential
GenevisibleiQ3TFQ1 MM

Family and domain databases

CDDicd12880 SPRYD7, 1 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR013320 ConA-like_dom_sf
IPR003877 SPRY_dom
IPR035766 SPRYD7
PANTHERiPTHR20951 PTHR20951, 1 hit
PfamiView protein in Pfam
PF00622 SPRY, 1 hit
SMARTiView protein in SMART
SM00449 SPRY, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSPRY7_MOUSE
AccessioniPrimary (citable) accession number: Q3TFQ1
Secondary accession number(s): Q8K1Y1
, Q9CU44, Q9D368, Q9D3D1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 27, 2006
Last modified: September 12, 2018
This is version 85 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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