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UniProtKB - Q3T7C8 (Q3T7C8_STRPU)
Protein
Submitted name:
Egg permeability glycoprotein
Gene
ABCB1
Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 470 – 477 | ATPPROSITE-ProRule annotation | 8 | |
Nucleotide bindingi | 1121 – 1128 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ABC-type transporter activity Source: InterPro
- ATPase-coupled transmembrane transporter activity Source: GO_Central
- ATP binding Source: UniProtKB-UniRule
GO - Biological processi
- transmembrane transport Source: GO_Central
Keywordsi
Ligand | ATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding |
Protein family/group databases
TCDBi | 3.A.1.201.15, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Submitted name: Egg permeability glycoproteinImported |
Gene namesi | Name:ABCB1Imported |
Organismi | Strongylocentrotus purpuratus (Purple sea urchin)Imported |
Taxonomic identifieri | 7668 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Echinodermata › Eleutherozoa › Echinozoa › Echinoidea › Euechinoidea › Echinacea › Camarodonta › Echinidea › Strongylocentrotidae › Strongylocentrotus |
Proteomesi |
|
Subcellular locationi
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 101 – 125 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 160 – 183 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 233 – 252 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 258 – 280 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 337 – 360 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 375 – 393 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 759 – 782 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 802 – 822 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 883 – 904 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 910 – 930 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 985 – 1005 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 1025 – 1043 | HelicalSequence analysisAdd BLAST | 19 |
Keywords - Cellular componenti
MembraneStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 105 – 401 | ABC transmembrane type-1InterPro annotationAdd BLAST | 297 | |
Domaini | 435 – 671 | ABC transporterInterPro annotationAdd BLAST | 237 | |
Domaini | 763 – 1051 | ABC transmembrane type-1InterPro annotationAdd BLAST | 289 | |
Domaini | 1086 – 1324 | ABC transporterInterPro annotationAdd BLAST | 239 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 82 | DisorderedSequence analysisAdd BLAST | 82 | |
Regioni | 675 – 738 | DisorderedSequence analysisAdd BLAST | 64 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 311 – 331 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 65 – 82 | Basic and acidic residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 685 – 700 | Acidic residuesSequence analysisAdd BLAST | 16 |
Keywords - Domaini
Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG0055, Eukaryota |
HOGENOMi | CLU_000604_17_2_1 |
OrthoDBi | 186078at2759 |
Family and domain databases
Gene3Di | 1.20.1560.10, 1 hit 3.40.50.300, 2 hits |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR027417, P-loop_NTPase IPR039421, Type_1_exporter |
PANTHERi | PTHR24221, PTHR24221, 1 hit |
Pfami | View protein in Pfam PF00664, ABC_membrane, 2 hits PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits SSF90123, SSF90123, 2 hits |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 2 hits PS00211, ABC_TRANSPORTER_1, 2 hits PS50893, ABC_TRANSPORTER_2, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q3T7C8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVEGDPPAVG FSNGNGTVQM NGNGASFDGP AVIDVSPVHE DAPSAKHARD
60 70 80 90 100
SPPPAYNDVD GTKEQENGGS VEGEGGEKEE KKETKVVGTF EVFRFATGLD
110 120 130 140 150
VVFILLALVI SLCHGVALPA VLLLFGEVTD SFITTASVNV TDNLAAFEES
160 170 180 190 200
VDSIITFSIY YSYLGCGVLA LAYFQVVLWD VAAERQIHKV RLRFFHAILR
210 220 230 240 250
QEIAWFDVHK GGELNTRLAD DIDKIRNGIG DKLGIMLQYT ATFVAGITIG
260 270 280 290 300
FVKSWKLTLV ILAVSLILIV PLVGSTSVII QRMTKQALDA YAKAGAIAGE
310 320 330 340 350
VFSGIRTVVA FNGEEKEMVR YSSNLDQAKS KTVKKDFATL LAQGFLFFSM
360 370 380 390 400
FSSYAIAFWY GTVLYLDNEI TPGDILTTFL AVLFGAFAIG QAGPNYSDFT
410 420 430 440 450
TARAAASSIW EVIDQIPTID CFSTDGKKEK ITGQVTFEGV HFSYPSRASV
460 470 480 490 500
KVLNGINLKV DVGKTVAMVG SSGCGKSTCI QLIQRFYDVA EGSIKIDGID
510 520 530 540 550
IRDLNVSWLR DHIGVVSQEP ILFATTIEEN IRYGRLDVTQ VEIEKAAEEA
560 570 580 590 600
NAHEFISKLP EGYSTLVGER GAQLSGGQKQ RIAIARALVR NPTILLLDEA
610 620 630 640 650
TSALDTESEA TVQLALEKAQ HGRTTLVIAH RLSTIFNSDL ICAFKEGIIS
660 670 680 690 700
EQGTHEELMK NEGGVYHTLV MKQGMKKEEE EEKKENEVPL DDDDDEEDDS
710 720 730 740 750
QGEKVYRAGS GKKKLTRVLS RTQSQMSGDE EKQDEDEYEK ELEKHFSMMR
760 770 780 790 800
VWKLNTPECG FILLGCIGAA INGAVQPGFA VVFSKILGAY SITDRAALFD
810 820 830 840 850
EVTIYCVLFA ALGLLSLLAS IIQGVGFGKS GGELTLRLRN MMFRAILRQN
860 870 880 890 900
ISFFDDKRNG TGALTTKLAT DVSLIQGVTG VRLGMIFEVL FNIGVGIVIS
910 920 930 940 950
FVYSWQIACL LLFAFLPILS LAGMIGWKIL QGNSIGTAGS QAEVGKLVSE
960 970 980 990 1000
CIENIRTVQS LNRGQTFHLK YCELQNPPYK QGIKGAFAAG LAFGFSQATI
1010 1020 1030 1040 1050
FFAYSATFRL GAHLVGTGDL TFPDVFLSFS ALMFGAFGLG RAAGSVPDFS
1060 1070 1080 1090 1100
KAKVATGELF YLVDRSPDID TFSDDGEKPA SYGGSVSLNN VRFRYPTRPD
1110 1120 1130 1140 1150
VPVLRGLSVS VDPGETLALV GSSGCGKSTT IQLMERFYDP HSGTVMFDSH
1160 1170 1180 1190 1200
DASLLNTRWQ RAQVGLVSQE PCLFDMSIAE NIKYGDNSRE VSIEDCIEAA
1210 1220 1230 1240 1250
KKSNIHDFVD SLPMKYDTNV GSKGTQLSGG QKQRIAIARA LVRNPKVLLL
1260 1270 1280 1290 1300
DEATSALDTE SERVVQDALD EAKKGRTCIT IAHRLSTIHN AEKIAVIREG
1310 1320
KLAEFGKHEE LMAMKQQYYS LYTAQSMQH
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A7M7LW81 | A0A7M7LW81_STRPU | Uncharacterized protein | 1,349 | Annotation score: | |||
A0A7M7HPM5 | A0A7M7HPM5_STRPU | Uncharacterized protein | 1,328 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY701853 mRNA Translation: AAW28777.1 |
RefSeqi | NP_001029122.1, NM_001033950.1 |
Genome annotation databases
EnsemblMetazoai | NM_001033950; NP_001029122; GeneID_591668 |
GeneIDi | 591668 |
KEGGi | spu:591668 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY701853 mRNA Translation: AAW28777.1 |
RefSeqi | NP_001029122.1, NM_001033950.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7668.SPU_001752-tr |
Protein family/group databases
TCDBi | 3.A.1.201.15, the atp-binding cassette (abc) superfamily |
Genome annotation databases
EnsemblMetazoai | NM_001033950; NP_001029122; GeneID_591668 |
GeneIDi | 591668 |
KEGGi | spu:591668 |
Organism-specific databases
CTDi | 5243 |
Phylogenomic databases
eggNOGi | KOG0055, Eukaryota |
HOGENOMi | CLU_000604_17_2_1 |
OrthoDBi | 186078at2759 |
Family and domain databases
Gene3Di | 1.20.1560.10, 1 hit 3.40.50.300, 2 hits |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR027417, P-loop_NTPase IPR039421, Type_1_exporter |
PANTHERi | PTHR24221, PTHR24221, 1 hit |
Pfami | View protein in Pfam PF00664, ABC_membrane, 2 hits PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits SSF90123, SSF90123, 2 hits |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 2 hits PS00211, ABC_TRANSPORTER_1, 2 hits PS50893, ABC_TRANSPORTER_2, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3T7C8_STRPU | |
Accessioni | Q3T7C8Primary (citable) accession number: Q3T7C8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | January 19, 2022 | |
This is version 115 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |