Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 76 (05 Jun 2019)
Sequence version 1 (11 Oct 2005)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Endo-alpha-N-acetylgalactosaminidase

Gene

engBF

Organism
Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi727ManganeseCombined sources1
Metal bindingi752ManganeseCombined sources1
Metal bindingi1299Manganese; via tele nitrogenCombined sources1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidaseImported, Hydrolase
LigandManganeseCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:MONOMER-16670

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
3.2.1.97 851

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
CBM32 Carbohydrate-Binding Module Family 32
GH101 Glycoside Hydrolase Family 101

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Endo-alpha-N-acetylgalactosaminidaseImported (EC:3.2.1.97Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:engBFImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri565042 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1940 – 1959HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 29Sequence analysisAdd BLAST29
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500422936930 – 1966Sequence analysisAdd BLAST1937

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q3T552

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q3T552

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q3T552

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1529 – 1634F5/8 type CInterPro annotationAdd BLAST106

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1543 – 1579DisorderedSequence analysisAdd BLAST37

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1449 – 1476Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14244 GH_101_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.260, 3 hits
2.60.40.1180, 1 hit
2.70.98.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008969 CarboxyPept-like_regulatory
IPR013320 ConA-like_dom_sf
IPR025706 Endoa_GalNAc
IPR000421 FA58C
IPR040633 Gal_mutarotas_3
IPR008979 Galactose-bd-like_sf
IPR040502 GalBD-like
IPR014718 GH-type_carb-bd
IPR040575 GH101_N
IPR035364 Glyco_hyd_101_beta
IPR013780 Glyco_hydro_b

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00754 F5_F8_type_C, 1 hit
PF18080 Gal_mutarotas_3, 1 hit
PF17974 GalBD_like, 1 hit
PF17995 GH101_N, 1 hit
PF17451 Glyco_hyd_101C, 1 hit
PF12905 Glyco_hydro_101, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49464 SSF49464, 1 hit
SSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50022 FA58C_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q3T552-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKKKTISAA LATALALTCM GSGGGTAFAV PLSDADLQTL ASQIQQINDT
60 70 80 90 100
SDSATASETP SAQADAVEGW TIDSNIAQGG EILEMANGWL HLKSTASNGN
110 120 130 140 150
AAANPSSSNN WPAVAVWGTD YDFSKAGSFH ATIKSPQEGS ANRFGFYLGY
160 170 180 190 200
NDPGSGLFIG YDSGGWFWQT YTGGGSGSWY SGARIAAPSA NEEHDIRVSW
210 220 230 240 250
TDAKVATLTV DGQKAFDVDY SAMTNLSNKL AIKAGSWKEL NEVTDVYIKD
260 270 280 290 300
FPEVVEAAKH AVSGKVVDAG GAAIEGATVR LDKTKVKTGA DGTFSFADIE
310 320 330 340 350
EGEHTLSIAK EGYEDVSQQV TVSGADLAID PITLNKTVQV ASETLKTKKM
360 370 380 390 400
EVQIKKNFPS VLQYTMTDGK VMYGQSKDVR TVEINGTNIE LGDDDVTFKK
410 420 430 440 450
VSDTEATYTL KVKDEAKKID AVITVQITVK ANQLHLNVTK IKNNLSEGIP
460 470 480 490 500
EGNGVEENAI QTLSFPNQSL VSVRSSQENA QFTGARMSSN TQKPGDTNFA
510 520 530 540 550
VTEDTNVTDS DYTYGFISGA GLSAGLWSNS EHDGTYVAAP VRGGSQNTRV
560 570 580 590 600
YATTQQTGDA TSLGLASAPW YYHRTVTDSK GKKYTVAETA LPQMAVAIAG
610 620 630 640 650
DENEDGAVNW QDGAIAYRDI MNNPYKSEEV PELVAWRIAM NFGSQAQNPF
660 670 680 690 700
LTTLDNVKKV ALNTDGLGQS VLLKGYGNEG HDSGHPDYGD IGQRLGGADD
710 720 730 740 750
MNTMMEEGSK YGARFGVHVN ASEMYPEAKA FSEDMVRRNS AGGLSYGWNW
760 770 780 790 800
LDQGVGIDGI YDLASGSRVS RFADLSKEVG DNMDFIYLDV WGNLTSSGSE
810 820 830 840 850
DSWETRKMSK MINDNGWRMT TEWGSGNEYD STFQHWAADL TYGGYTSKGE
860 870 880 890 900
NSEVMRFLRN HQKDSWVGDY PQYGGAANAP LLGGYNMKDF EGWQGRNDYA
910 920 930 940 950
AYIKNLYTHD VSTKFIQHFK VTRWVNNPLL TADNGNAAAV SDPNTNNGNE
960 970 980 990 1000
QITLKDSNGN VVVVSRGSND TSSAAYRQRT ITFNGVKVAS GVVSAGDGSA
1010 1020 1030 1040 1050
TGDESYLLPW MWDSFTGKLV KDSEQKLYHW NTKGGTTTWT LPDSWKNLSS
1060 1070 1080 1090 1100
VKVYQLTDQG KTNEQTVAVS GGKVTLTADA ETPYVVYKGE AKQIQVNWSE
1110 1120 1130 1140 1150
GMHVVDAGFN GGSNTLTDNW TVGGSGKAEV EGDNNAMLRL TGKVDVSQRL
1160 1170 1180 1190 1200
TDLKAGQKYA LYVGVDNRST GDASVTVTSG GKVLATNSTG KSIAKNYIKA
1210 1220 1230 1240 1250
YGHNTNSNTE NGSSYFQNMY VFFTAPENGD ATVTLSHKST DGAHTYFDDV
1260 1270 1280 1290 1300
RIVENQYSGI TYEKDGTLKS LTNGFENNAQ GIWPFVVSGS EGVEDNRIHL
1310 1320 1330 1340 1350
SELHAPFTRA GWDVKKMDDV LDGTWSVKVN GLTQKGTLVY QTIPQNVKFE
1360 1370 1380 1390 1400
AGAKYKVSFD YQSGSDDIYA IAVGQGEYSA GSVKLTNLKK ALGETGKAEF
1410 1420 1430 1440 1450
ELTGGVNGDS WFGIYSTATA PDLQGSTGNA QDFGGYKDFV LDNLKIERIE
1460 1470 1480 1490 1500
SQTRTKAEAQ DKVKEIRGKY DSKRAELSDA AWQQYQDTLV KARVLINKNG
1510 1520 1530 1540 1550
ATAEDFTKAY DILVALDEYM KTAPGNESSD KYDVAADGSD ELGGYTVATG
1560 1570 1580 1590 1600
SEEPTAGLPS EGPADLAQDG NDSTHWHTSW SENAVGNGTA WYQFNLNEPT
1610 1620 1630 1640 1650
TINGLRYLPR SGGMNANGKI KGYKITLTLA DGTTKDVVTD AEFSTTTMWQ
1660 1670 1680 1690 1700
KASFDAVENV TAVRLTVLSS AGQSDSQANK FASAAELRLT TDREVEEETV
1710 1720 1730 1740 1750
APDKTDLNDT IAKANGLKES DYTAESWTAL VKAREAAQAV ADNDKATAYD
1760 1770 1780 1790 1800
VALALTNLES AIAGLEKTGE EPGPGPVEVN KTDLQTAVNK ASKLEKADYT
1810 1820 1830 1840 1850
TNSWEAFAEA LKAAQQVLDN KNATQQDVDT ALSALQDAIS KLEAATEPKP
1860 1870 1880 1890 1900
NPEPGVVDKA ALNATINKAA AINLGLYTDD SANALRAALK KAREVSDNSN
1910 1920 1930 1940 1950
ATQKQVDAAR EALEKAIAAL VKRPAAKGDG NVVSNTGSDV ATIALAGLLL
1960
AGAGAAIAYR RNREQL
Length:1,966
Mass (Da):211,064
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i953956E7D58FDFF9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY836679 Genomic DNA Translation: AAX44931.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY836679 Genomic DNA Translation: AAX44931.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ZXQX-ray2.00A340-1694[»]
SMRiQ3T552
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiCBM32 Carbohydrate-Binding Module Family 32
GH101 Glycoside Hydrolase Family 101

Proteomic databases

PRIDEiQ3T552

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-16670
BRENDAi3.2.1.97 851

Miscellaneous databases

EvolutionaryTraceiQ3T552

Family and domain databases

CDDicd14244 GH_101_like, 1 hit
Gene3Di2.60.120.260, 3 hits
2.60.40.1180, 1 hit
2.70.98.10, 1 hit
InterProiView protein in InterPro
IPR008969 CarboxyPept-like_regulatory
IPR013320 ConA-like_dom_sf
IPR025706 Endoa_GalNAc
IPR000421 FA58C
IPR040633 Gal_mutarotas_3
IPR008979 Galactose-bd-like_sf
IPR040502 GalBD-like
IPR014718 GH-type_carb-bd
IPR040575 GH101_N
IPR035364 Glyco_hyd_101_beta
IPR013780 Glyco_hydro_b
PfamiView protein in Pfam
PF00754 F5_F8_type_C, 1 hit
PF18080 Gal_mutarotas_3, 1 hit
PF17974 GalBD_like, 1 hit
PF17995 GH101_N, 1 hit
PF17451 Glyco_hyd_101C, 1 hit
PF12905 Glyco_hydro_101, 1 hit
SUPFAMiSSF49464 SSF49464, 1 hit
SSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50022 FA58C_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ3T552_BIFL2
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3T552
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 5, 2019
This is version 76 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again