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Protein

Elongation factor 1-gamma

Gene

EEF1G

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probably plays a role in anchoring the complex to other cellular components.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor 1-gamma
Short name:
EF-1-gamma
Alternative name(s):
eEF-1B gamma
Gene namesi
Name:EEF1G
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002846542 – 440Elongation factor 1-gammaAdd BLAST439

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Modified residuei147N6-acetyllysineBy similarity1
Modified residuei212N6-acetyllysineBy similarity1
Cross-linki256Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)By similarity
Cross-linki288Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei404N6-acetyllysineBy similarity1
Modified residuei437N6-acetyllysine; alternateBy similarity1
Modified residuei437N6-malonyllysine; alternateBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiQ3SZV3
PeptideAtlasiQ3SZV3
PRIDEiQ3SZV3

Interactioni

Subunit structurei

EF-1 is composed of four subunits: alpha, beta, delta, and gamma.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000015716

Structurei

3D structure databases

ProteinModelPortaliQ3SZV3
SMRiQ3SZV3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 87GST N-terminalAdd BLAST86
Domaini88 – 216GST C-terminalAdd BLAST129
Domaini279 – 440EF-1-gamma C-terminalPROSITE-ProRule annotationAdd BLAST162

Phylogenomic databases

eggNOGiKOG0867 Eukaryota
KOG1627 Eukaryota
COG0625 LUCA
HOGENOMiHOG000201196
HOVERGENiHBG051444
InParanoidiQ3SZV3
KOiK03233

Family and domain databases

Gene3Di3.30.70.1010, 1 hit
InterProiView protein in InterPro
IPR001662 EF1B_G_C
IPR036433 EF1B_G_C_sf
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00647 EF1G, 1 hit
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
SMARTiView protein in SMART
SM01183 EF1G, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
SSF89942 SSF89942, 1 hit
PROSITEiView protein in PROSITE
PS50040 EF1G_C, 1 hit
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3SZV3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAGTLYTYP ENWRAFKALI AAQYSGAQVR VLSAPPHFHF GQTNRTPEFL
60 70 80 90 100
RKFPAGKVPA FEGDDGFCVF ESNAIAYYVS NEELRGSTPE AAAQVVQWVS
110 120 130 140 150
FADSDIVPPA STWVFPTLGI MHHNKQATEN AKEEVRRILG LLDAHLKTRT
160 170 180 190 200
FLVGERVTLA DITVVCTLLW LYKQVLEPSF RQAFPNTNRW FLTCINQPQF
210 220 230 240 250
RAVLGEVKLC EKMAQFDAKK FAESQPKKDT PRKEKGSREE KLKPQAERKE
260 270 280 290 300
GKEEKKAAAP APEEELDECE QALAAEPKAK DPFAHLPKST FVLDEFKRKY
310 320 330 340 350
SNEDTLSVAL PYFWDHFDKD GWSLWYSEYR FPEELTQTFM SCNLITGMFQ
360 370 380 390 400
RLDKLRKNAF ASVILFGTNN SSSISGVWDF RGQELAFPLS PDWQVDYESY
410 420 430 440
TWRKLDPGSE ETQTLVREYF CWEGAFQHVG KAFNQGKIFK
Length:440
Mass (Da):50,378
Last modified:October 11, 2005 - v1
Checksum:i295A874E422B825C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102691 mRNA Translation: AAI02692.1
RefSeqiNP_001035577.1, NM_001040487.2
UniGeneiBt.62921

Genome annotation databases

GeneIDi326581
KEGGibta:326581

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102691 mRNA Translation: AAI02692.1
RefSeqiNP_001035577.1, NM_001040487.2
UniGeneiBt.62921

3D structure databases

ProteinModelPortaliQ3SZV3
SMRiQ3SZV3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000015716

Proteomic databases

PaxDbiQ3SZV3
PeptideAtlasiQ3SZV3
PRIDEiQ3SZV3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi326581
KEGGibta:326581

Organism-specific databases

CTDi1937

Phylogenomic databases

eggNOGiKOG0867 Eukaryota
KOG1627 Eukaryota
COG0625 LUCA
HOGENOMiHOG000201196
HOVERGENiHBG051444
InParanoidiQ3SZV3
KOiK03233

Family and domain databases

Gene3Di3.30.70.1010, 1 hit
InterProiView protein in InterPro
IPR001662 EF1B_G_C
IPR036433 EF1B_G_C_sf
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00647 EF1G, 1 hit
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
SMARTiView protein in SMART
SM01183 EF1G, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
SSF89942 SSF89942, 1 hit
PROSITEiView protein in PROSITE
PS50040 EF1G_C, 1 hit
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiEF1G_BOVIN
AccessioniPrimary (citable) accession number: Q3SZV3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: October 11, 2005
Last modified: October 25, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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