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Protein

Zinc finger protein 345

Gene

ZNF345

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri62 – 84C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri90 – 112C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri118 – 140C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri146 – 168C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri174 – 196C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri202 – 224C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri230 – 252C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri258 – 280C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri286 – 308C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri314 – 336C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri342 – 364C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri370 – 392C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri398 – 420C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri426 – 448C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri454 – 476C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 345
Gene namesi
Name:ZNF345
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002446011 – 487Zinc finger protein 345Add BLAST487

Proteomic databases

PRIDEiQ3SYV7

Expressioni

Gene expression databases

BgeeiENSBTAG00000008902 Expressed in 10 organ(s), highest expression level in spleen
ExpressionAtlasiQ3SYV7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ3SYV7
SMRiQ3SYV7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri62 – 84C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri90 – 112C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri118 – 140C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri146 – 168C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri174 – 196C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri202 – 224C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri230 – 252C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri258 – 280C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri286 – 308C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri314 – 336C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri342 – 364C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri370 – 392C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri398 – 420C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri426 – 448C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri454 – 476C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00930000150816
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiQ3SYV7
OMAiECKACGM

Family and domain databases

InterProiView protein in InterPro
IPR017114 YY-1-like
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 14 hits
PIRSFiPIRSF037113 TF_Yin_yang, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 15 hits
SUPFAMiSSF57667 SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 15 hits
PS50157 ZINC_FINGER_C2H2_2, 15 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q3SYV7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERLIKNSIA YSRFRGDWEC KSQFERKQES QEGHLSQMIF TPEDMPTFNT
60 70 80 90 100
QHQRIHTDEK LLECKECGKD FSFVSVLIRH QRIHTGEKPY ECKECGKAFG
110 120 130 140 150
SGANLAYHQR IHTGEKPYEC NECGKAFGSG SNLTHHQRIH TGEKPYECKE
160 170 180 190 200
CGKAFSFGSG LIRHQIIHSG EKPYECKVCG KSFSFESALT RHHRIHTGEK
210 220 230 240 250
PYECKDCGKA FGSGSNLTQH RRVHTGEKPY ECKGCGMAFS SGSALTRHQR
260 270 280 290 300
IHTGEKPYIC NECGKAFSFG SALTRHQRIH TGEKPYVCKE CGKAFNSGSD
310 320 330 340 350
LTQHQRIHTG EKPYECKECE KAFRSGSKLI QHQRMHTGEK PYECKECGKA
360 370 380 390 400
FSSGSDLTQH QRIHTGEKPY ECKECGKAFA SGSKLIQHQL IHTGEKPYEC
410 420 430 440 450
RECRKSFSSG SALNRHQRIH TGQKPYECKE CEKTFGTGST LTQHQRMHTA
460 470 480
EKLYECKACG KALGRGSEIQ QHKKNHAGEK LCELETP
Length:487
Mass (Da):55,270
Last modified:October 11, 2005 - v1
Checksum:i7362A22FB24C3F9F
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1MJ88F1MJ88_BOVIN
Zinc finger protein 345
ZNF345
1,051Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103362 mRNA Translation: AAI03363.1
RefSeqiNP_001030404.1, NM_001035327.1
UniGeneiBt.41970

Genome annotation databases

EnsembliENSBTAT00000026567; ENSBTAP00000026567; ENSBTAG00000008902
GeneIDi518207
KEGGibta:518207

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103362 mRNA Translation: AAI03363.1
RefSeqiNP_001030404.1, NM_001035327.1
UniGeneiBt.41970

3D structure databases

ProteinModelPortaliQ3SYV7
SMRiQ3SYV7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ3SYV7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000026567; ENSBTAP00000026567; ENSBTAG00000008902
GeneIDi518207
KEGGibta:518207

Organism-specific databases

CTDi25850

Phylogenomic databases

GeneTreeiENSGT00930000150816
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiQ3SYV7
OMAiECKACGM

Gene expression databases

BgeeiENSBTAG00000008902 Expressed in 10 organ(s), highest expression level in spleen
ExpressionAtlasiQ3SYV7 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR017114 YY-1-like
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 14 hits
PIRSFiPIRSF037113 TF_Yin_yang, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 15 hits
SUPFAMiSSF57667 SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 15 hits
PS50157 ZINC_FINGER_C2H2_2, 15 hits
ProtoNetiSearch...

Entry informationi

Entry nameiZN345_BOVIN
AccessioniPrimary (citable) accession number: Q3SYV7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 11, 2005
Last modified: November 7, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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