UniProtKB - Q3SYK8 (Q3SYK8_HUMAN)
Protein
Submitted name:
NUMA1 protein
Gene
NUMA1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: NUMA1 proteinImported |
Gene namesi | Name:NUMA1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Golgi apparatus
- Golgi membrane Source: InterPro
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 549 – 596 | DisorderedSequence analysisAdd BLAST | 48 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 216 – 250 | Sequence analysisAdd BLAST | 35 | |
Coiled coili | 278 – 319 | Sequence analysisAdd BLAST | 42 | |
Coiled coili | 327 – 400 | Sequence analysisAdd BLAST | 74 | |
Coiled coili | 415 – 449 | Sequence analysisAdd BLAST | 35 | |
Coiled coili | 468 – 491 | Sequence analysisAdd BLAST | 24 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 549 – 564 | PolarSequence analysisAdd BLAST | 16 | |
Compositional biasi | 565 – 596 | PolyampholyteSequence analysisAdd BLAST | 32 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
OrthoDBi | 524033at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR026650, NUMA1 |
PANTHERi | PTHR18902:SF24, PTHR18902:SF24, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q3SYK8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTLHATRGAA LLSWVNSLHV ADPVEAVLQL QDCSIFIKII DRIHGTEEGQ
60 70 80 90 100
QILKQPVSER LDFVCSFLQK NRKHPSSPEC LVSAQKVLEG SELELAKMTM
110 120 130 140 150
LLLYHSTMSS KSPRDWEQFE YKIQAELAVI LKFVLDHEDG LNLNEDLENF
160 170 180 190 200
LQKAPVPSTC SSTFPEELSP PSHQAKREIR FLELQKVASS SSGNNFLSGS
210 220 230 240 250
PASPMGDILQ TPQFQMRRLK KQLADERSNR DELELELAEN RKLLTEKDAQ
260 270 280 290 300
IAMMQQRIDR LALLNEKQAA SPLEPKELEE LRDKNESLTM RLHETLKQCQ
310 320 330 340 350
DLKTEKSQMD RKINQLSEEN GDLSFKLREF ASHLQQLQDA LNELTEEHSK
360 370 380 390 400
ATQEWLEKQA QLEKELSAAL QDKKCLEEKN EILQGKLSQL EEHLSQLQDN
410 420 430 440 450
PPQEKGEVLG DVLQLETLKQ EAATLAANNT QLQARVEMLE TERGQQEAKL
460 470 480 490 500
LAERGHFEEE KQQLSSLITD LQSSISNLSQ AKEELEQASQ AHGARLTAQV
510 520 530 540 550
ASLTSELTTL NATIQQQDQE LAGLKQQAKE KQAQLAQTLQ QQEQASQGLR
560 570 580 590 600
HQVEQLSSSL KQKEQQLKEV AEKQEATRQD HAQQLATAAE EREASLRERD
610 620 630 640 650
AALKQLEALE KEKAAKLEIL QQQLQVANEA RDSAQTSVTQ AQREKAELSR
660 670 680 690
KVEELQACVE TARQEQHEAQ AQVAELELQL RSEQQKAKKK K
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 691 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC027493 mRNA Translation: AAH27493.1 BC103765 mRNA Translation: AAI03766.1 |
RefSeqi | NP_006176.2, NM_006185.3 |
Genome annotation databases
GeneIDi | 4926 |
KEGGi | hsa:4926 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC027493 mRNA Translation: AAH27493.1 BC103765 mRNA Translation: AAI03766.1 |
RefSeqi | NP_006176.2, NM_006185.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q3SYK8 |
Protocols and materials databases
DNASUi | 4926 |
Genome annotation databases
GeneIDi | 4926 |
KEGGi | hsa:4926 |
Organism-specific databases
CTDi | 4926 |
PharmGKBi | PA31844 |
Phylogenomic databases
OrthoDBi | 524033at2759 |
Miscellaneous databases
BioGRID-ORCSi | 4926, 439 hits in 880 CRISPR screens |
ChiTaRSi | NUMA1, human |
GenomeRNAii | 4926 |
Family and domain databases
InterProi | View protein in InterPro IPR026650, NUMA1 |
PANTHERi | PTHR18902:SF24, PTHR18902:SF24, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3SYK8_HUMAN | |
Accessioni | Q3SYK8Primary (citable) accession number: Q3SYK8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | February 10, 2021 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |