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Entry version 89 (12 Aug 2020)
Sequence version 1 (11 Oct 2005)
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Protein

Keratin-associated protein 19-7

Gene

KRTAP19-7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q3SYF9

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6805567, Keratinization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Keratin-associated protein 19-7
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KRTAP19-7
Synonyms:KAP19.7
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000244362.2

Human Gene Nomenclature Database

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HGNCi
HGNC:18942, KRTAP19-7

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q3SYF9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Keratin

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134868084

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q3SYF9, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KRTAP19-7

Domain mapping of disease mutations (DMDM)

More...
DMDMi
88909173

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002239091 – 63Keratin-associated protein 19-7Add BLAST63

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3SYF9

PeptideAtlas

More...
PeptideAtlasi
Q3SYF9

PRoteomics IDEntifications database

More...
PRIDEi
Q3SYF9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
61860

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q3SYF9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3SYF9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000244362, Expressed in ectocervix and 18 other tissues

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000244362, Tissue enriched (skin)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with hair keratins.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q3SYF9
With#Exp.IntAct
ANKS1A [Q49AR9]3EBI-10241353,EBI-11954519
ARID5A [Q03989]3EBI-10241353,EBI-948603
ARMC7 [Q9H6L4]3EBI-10241353,EBI-742909
ATPAF2 [Q8N5M1]3EBI-10241353,EBI-1166928
ATXN1L [P0C7T5]3EBI-10241353,EBI-8624731
BAHD1 [Q8TBE0]3EBI-10241353,EBI-742750
BHLHE40 [O14503]3EBI-10241353,EBI-711810
CAMK2A [Q9UQM7]3EBI-10241353,EBI-1383687
CAMK2B [Q13554]3EBI-10241353,EBI-1058722
CATSPER1 [Q8NEC5]3EBI-10241353,EBI-744545
CCDC24 [Q8N4L8]3EBI-10241353,EBI-1104933
CCNK - isoform 2 [O75909-2]3EBI-10241353,EBI-12010594
COL8A1 [P27658]3EBI-10241353,EBI-747133
CYSRT1 [A8MQ03]3EBI-10241353,EBI-3867333
DAB1 [O75553]3EBI-10241353,EBI-7875264
DAZAP2 [Q15038]3EBI-10241353,EBI-724310
DTX2 [Q86UW9]3EBI-10241353,EBI-740376
EVX2 [Q03828]3EBI-10241353,EBI-17280301
FAM168A - isoform 2 [Q92567-2]3EBI-10241353,EBI-11978259
FOXD2 [O60548]3EBI-10241353,EBI-17282008
FOXH1 [O75593]3EBI-10241353,EBI-1759806
FOXI1 - isoform 2 [Q12951-2]3EBI-10241353,EBI-12018822
GLIS2 [Q9BZE0]3EBI-10241353,EBI-7251368
GNE - isoform 2 [Q9Y223-2]3EBI-10241353,EBI-11975289
GSX1 [Q9H4S2]3EBI-10241353,EBI-18011701
HOMER3 [Q9NSC5]3EBI-10241353,EBI-748420
HOXA1 [P49639]3EBI-10241353,EBI-740785
HSF4 - isoform HSF4A [Q9ULV5-2]3EBI-10241353,EBI-12056251
IRX6 [P78412]3EBI-10241353,EBI-12100506
KPRP [Q5T749]3EBI-10241353,EBI-10981970
KRT34 [O76011]3EBI-10241353,EBI-1047093
KRTAP10-8 [P60410]3EBI-10241353,EBI-10171774
KRTAP12-3 [P60328]3EBI-10241353,EBI-11953334
KRTAP12-4 [P60329]3EBI-10241353,EBI-10176396
KRTAP26-1 [Q6PEX3]3EBI-10241353,EBI-3957672
KRTAP3-3 [Q9BYR6]3EBI-10241353,EBI-3957694
KRTAP9-2 [Q9BYQ4]3EBI-10241353,EBI-1044640
LONRF1 [Q17RB8]3EBI-10241353,EBI-2341787
MAPK1IP1L [Q8NDC0]3EBI-10241353,EBI-741424
MKRN3 [Q13064]3EBI-10241353,EBI-2340269
NAF1 [Q96HR8]3EBI-10241353,EBI-2515597
NEU4 - isoform 2 [Q8WWR8-2]3EBI-10241353,EBI-10277551
NOTO [A8MTQ0]3EBI-10241353,EBI-17490746
NOXA1 - isoform 2 [Q86UR1-2]3EBI-10241353,EBI-12025760
OTX1 [P32242]3EBI-10241353,EBI-740446
PATZ1 - isoform 4 [Q9HBE1-4]3EBI-10241353,EBI-11022007
PAX7 - isoform 2 [P23759-2]3EBI-10241353,EBI-12859446
PITX1 [P78337]3EBI-10241353,EBI-748265
PITX2 - isoform PTX2C [Q99697-2]3EBI-10241353,EBI-12138495
PLSCR3 [Q9NRY6]3EBI-10241353,EBI-750734
PLSCR4 [Q9NRQ2]3EBI-10241353,EBI-769257
POU2AF1 [Q16633]3EBI-10241353,EBI-943588
POU4F2 [Q12837]3EBI-10241353,EBI-17236143
PROP1 [O75360]3EBI-10241353,EBI-9027467
PRR13 [Q9NZ81]3EBI-10241353,EBI-740924
PSMB1 [P20618]3EBI-10241353,EBI-372273
PSMB2 [P49721]3EBI-10241353,EBI-359335
RBPMS [Q93062]3EBI-10241353,EBI-740322
RBPMS - isoform C [Q93062-3]6EBI-10241353,EBI-740343
RBPMS2 [Q6ZRY4]3EBI-10241353,EBI-11987469
RHOXF2 [Q9BQY4]6EBI-10241353,EBI-372094
RNF44 [Q7L0R7]3EBI-10241353,EBI-2845060
ROR2 [Q01974]3EBI-10241353,EBI-6422642
SMN2 [Q16637]3EBI-10241353,EBI-395421
SPAG8 - isoform 2 [Q99932-2]3EBI-10241353,EBI-11959123
TCAP [O15273]3EBI-10241353,EBI-954089
TCF7L2 - isoform 10 [Q9NQB0-10]3EBI-10241353,EBI-11746252
TEKT5 [Q96M29]3EBI-10241353,EBI-10239812
TEX37 [Q96LM6]3EBI-10241353,EBI-743976
TFAP2D [Q7Z6R9]3EBI-10241353,EBI-11952651
TLE5 - isoform 2 [Q08117-2]3EBI-10241353,EBI-11741437
TLX3 [O43711]3EBI-10241353,EBI-3939165
TNIP1 [Q15025]3EBI-10241353,EBI-357849
TOLLIP [Q9H0E2]3EBI-10241353,EBI-74615
TPRX1 - isoform 2 [Q8N7U7-2]3EBI-10241353,EBI-14115717
VAC14 [Q08AM6]6EBI-10241353,EBI-2107455
VENTX [O95231]3EBI-10241353,EBI-10191303
VGLL3 - isoform 2 [A8MV65-2]3EBI-10241353,EBI-11957216
VPS37C [A5D8V6]3EBI-10241353,EBI-2559305
ZIC1 [Q15915]3EBI-10241353,EBI-11963196

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
130657, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q3SYF9, 79 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000334696

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q3SYF9, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the KRTAP type 19 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502THDW, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183791

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3SYF9

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR021743, KRTAP_type6/8/16/19/20/21

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11759, KRTAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q3SYF9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSYSGSYYGG LGYGCGGFGG LGYGYSCGCG SFRRLGYGCG YGGYRYSCCH
60
PSCYGGYWSS GFY
Length:63
Mass (Da):6,644
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAC24810FC35B6F09
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB096949 mRNA Translation: BAE46364.1
BC103836 mRNA Translation: AAI03837.1
BC103837 mRNA Translation: AAI03838.1
BC103838 mRNA Translation: AAI03839.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13599.1

NCBI Reference Sequences

More...
RefSeqi
NP_853645.1, NM_181614.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000334849; ENSP00000334696; ENSG00000244362

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
337974

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:337974

UCSC genome browser

More...
UCSCi
uc011adb.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB096949 mRNA Translation: BAE46364.1
BC103836 mRNA Translation: AAI03837.1
BC103837 mRNA Translation: AAI03838.1
BC103838 mRNA Translation: AAI03839.1
CCDSiCCDS13599.1
RefSeqiNP_853645.1, NM_181614.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi130657, 5 interactors
IntActiQ3SYF9, 79 interactors
STRINGi9606.ENSP00000334696

PTM databases

iPTMnetiQ3SYF9
PhosphoSitePlusiQ3SYF9

Polymorphism and mutation databases

BioMutaiKRTAP19-7
DMDMi88909173

Proteomic databases

PaxDbiQ3SYF9
PeptideAtlasiQ3SYF9
PRIDEiQ3SYF9
ProteomicsDBi61860

Genome annotation databases

EnsembliENST00000334849; ENSP00000334696; ENSG00000244362
GeneIDi337974
KEGGihsa:337974
UCSCiuc011adb.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
337974
EuPathDBiHostDB:ENSG00000244362.2

GeneCards: human genes, protein and diseases

More...
GeneCardsi
KRTAP19-7
HGNCiHGNC:18942, KRTAP19-7
HPAiENSG00000244362, Tissue enriched (skin)
neXtProtiNX_Q3SYF9
PharmGKBiPA134868084

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502THDW, Eukaryota
GeneTreeiENSGT00950000183791
InParanoidiQ3SYF9

Enzyme and pathway databases

PathwayCommonsiQ3SYF9
ReactomeiR-HSA-6805567, Keratinization

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
337974, 21 hits in 841 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
337974
PharosiQ3SYF9, Tdark

Protein Ontology

More...
PROi
PR:Q3SYF9
RNActiQ3SYF9, protein

Gene expression databases

BgeeiENSG00000244362, Expressed in ectocervix and 18 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR021743, KRTAP_type6/8/16/19/20/21
PfamiView protein in Pfam
PF11759, KRTAP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKR197_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3SYF9
Secondary accession number(s): Q08EP7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: October 11, 2005
Last modified: August 12, 2020
This is version 89 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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