MOGAT2

Functionⁱ

Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.1 Publication

Catalytic activityⁱ

Acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.

Enzyme regulationⁱ

Inhibited by oleic acid and sphingosine, while it is stimulated by phosphatidylcholine, phosphatidylserine and phosphatidic acid.By similarity

Kineticsⁱ

K_M=
45 µM for sn-1-monooleoylglycerol
1 Publication
Manual assertion based on experiment inⁱ
- Ref.1
  "MGAT2, a monoacylglycerol acyltransferase expressed in the small intestine."
  Yen C.-L.E., Farese R.V. Jr.
  J. Biol. Chem. 278:18532-18537(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), ALTERNATIVE SPLICING (ISOFORM 3), FUNCTION, SUBCELLULAR LOCATION, BIOPHYSICOCHEMICAL PROPERTIES, TISSUE SPECIFICITY.

Pathwayⁱ: triacylglycerol biosynthesis

This protein is involved in the pathway triacylglycerol biosynthesis, which is part of Glycerolipid metabolism.
View all proteins of this organism that are known to be involved in the pathway triacylglycerol biosynthesis and in Glycerolipid metabolism.

GO - Molecular functionⁱ

2-acylglycerol O-acyltransferase activity Source: Reactome
acetyltransferase activity Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

diacylglycerol biosynthetic process Source: Ensembl
glycerol metabolic process Source: UniProtKB-KW
intestinal absorption Source: Ensembl
triglyceride biosynthetic process Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Acyltransferase, Transferase
Biological process	Glycerol metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BRENDAⁱ	2.3.1.22 2681
Reactomeⁱ	R-HSA-75109 Triglyceride biosynthesis
UniPathwayⁱ	UPA00282

Chemistry databases

SwissLipidsⁱ	SLP:000000299

SwissLipidsⁱ

SLP:000000299

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 2-acylglycerol O-acyltransferase 2 (EC:2.3.1.22) Alternative name(s): Acyl-CoA:monoacylglycerol acyltransferase 2 Short name: MGAT2 Short name: hMGAT2 Diacylglycerol O-acyltransferase candidate 5 Short name: hDC5 Diacylglycerol acyltransferase 2-like protein 5 Monoacylglycerol O-acyltransferase 2
Gene namesⁱ	Name:MOGAT2 Synonyms:DC5, DGAT2L5
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 11

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000166391.14
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:23248 MOGAT2
MIMⁱ	610270 gene
neXtProtⁱ	NX_Q3SYC2

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	23 – 37	HelicalSequence analysisAdd BLAST	15
Transmembraneⁱ	38 – 59	HelicalSequence analysisAdd BLAST	22
Transmembraneⁱ	103 – 123	HelicalSequence analysisAdd BLAST	21

Keywords - Cellular componentⁱ

Endoplasmic reticulum, Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	80168
Open Targets More...OpenTargetsⁱ	ENSG00000166391
PharmGKBⁱ	PA134936582

Chemistry databases

ChEMBLⁱ	CHEMBL2439944

ChEMBLⁱ

CHEMBL2439944

Polymorphism and mutation databases

BioMutaⁱ	MOGAT2
DMDMⁱ	114150036

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000249062	1 – 334	2-acylglycerol O-acyltransferase 2Add BLAST		334

Proteomic databases

PaxDbⁱ	Q3SYC2
PeptideAtlas More...PeptideAtlasⁱ	Q3SYC2
PRIDEⁱ	Q3SYC2
ProteomicsDBⁱ	61855 61856 [Q3SYC2-2] 61857 [Q3SYC2-3]

PTM databases

iPTMnetⁱ	Q3SYC2
PhosphoSitePlusⁱ	Q3SYC2

Expressionⁱ

Tissue specificityⁱ

Highly expressed in liver, small intestine, colon, stomach and kidney.2 Publications

Gene expression databases

Bgeeⁱ	ENSG00000166391
CleanExⁱ	HS_MOGAT2
Genevisibleⁱ	Q3SYC2 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA028834

HPAⁱ

HPA028834

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	123154, 2 interactors
STRINGⁱ	9606.ENSP00000198801

Chemistry databases

BindingDBⁱ

Q3SYC2

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q3SYC2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the diacylglycerol acyltransferase family.Curated

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG0831 Eukaryota ENOG410XTG3 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00750000117391
HOGENOMⁱ	HOG000179738
HOVERGENⁱ	HBG065791
InParanoidⁱ	Q3SYC2
KEGG Orthology (KO) More...KOⁱ	K14457
OMAⁱ	RLGFIKI
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0BGQ
PhylomeDBⁱ	Q3SYC2
TreeFamⁱ	TF314707

Family and domain databases

InterProⁱ	View protein in InterPro IPR007130 DAGAT
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03982 DAGAT, 1 hit

Sequences (3)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform 1 (identifier: Q3SYC2-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MVEFAPLFMP WERRLQTLAV LQFVFSFLAL AEICTVGFIA LLFTRFWLLT 
        60         70         80         90        100
VLYAAWWYLD RDKPRQGGRH IQAIRCWTIW KYMKDYFPIS LVKTAELDPS 
       110        120        130        140        150
RNYIAGFHPH GVLAVGAFAN LCTESTGFSS IFPGIRPHLM MLTLWFRAPF 
       160        170        180        190        200
FRDYIMSAGL VTSEKESAAH ILNRKGGGNL LGIIVGGAQE ALDARPGSFT 
       210        220        230        240        250
LLLRNRKGFV RLALTHGAPL VPIFSFGEND LFDQIPNSSG SWLRYIQNRL 
       260        270        280        290        300
QKIMGISLPL FHGRGVFQYS FGLIPYRRPI TTVVGKPIEV QKTLHPSEEE 
       310        320        330 
VNQLHQRYIK ELCNLFEAHK LKFNIPADQH LEFC

Length:334

Mass (Da):38,196

Last modified:September 5, 2006 - v2

Checksum:ⁱ57C4A964BAFA76BD

GO

Isoform 2 (identifier: Q3SYC2-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-82: Missing.

« Hide

        10         20         30         40         50
MKDYFPISLV KTAELDPSRN YIAGFHPHGV LAVGAFANLC TESTGFSSIF 
        60         70         80         90        100
PGIRPHLMML TLWFRAPFFR DYIMSAGLVT SEKESAAHIL NRKGGGNLLG 
       110        120        130        140        150
IIVGGAQEAL DARPGSFTLL LRNRKGFVRL ALTHGAPLVP IFSFGENDLF 
       160        170        180        190        200
DQIPNSSGSW LRYIQNRLQK IMGISLPLFH GRGVFQYSFG LIPYRRPITT 
       210        220        230        240        250
VVGKPIEVQK TLHPSEEEVN QLHQRYIKEL CNLFEAHKLK FNIPADQHLE 

FC

Note: No experimental confirmation available.

Show »

Length:252

Mass (Da):28,283

Checksum:ⁱ902B6B67B2E8CC02

GO

Isoform 3 (identifier: Q3SYC2-3) [UniParc]FASTA Add to basket

Also known as: MGAT2V, Trunc

The sequence of this isoform differs from the canonical sequence as follows:
218-284: APLVPIFSFG...PYRRPITTVV → YQASGKSTLG...PQRRLSDLRN
285-334: Missing.

« Hide

        10         20         30         40         50
MVEFAPLFMP WERRLQTLAV LQFVFSFLAL AEICTVGFIA LLFTRFWLLT 
        60         70         80         90        100
VLYAAWWYLD RDKPRQGGRH IQAIRCWTIW KYMKDYFPIS LVKTAELDPS 
       110        120        130        140        150
RNYIAGFHPH GVLAVGAFAN LCTESTGFSS IFPGIRPHLM MLTLWFRAPF 
       160        170        180        190        200
FRDYIMSAGL VTSEKESAAH ILNRKGGGNL LGIIVGGAQE ALDARPGSFT 
       210        220        230        240        250
LLLRNRKGFV RLALTHGYQA SGKSTLGSVG NWQGFYFGGK MAETNADSIL 
       260        270        280 
VEIFSPFTIK IIFWCLMPKY LEKFPQRRLS DLRN

Show »

Length:284

Mass (Da):32,298

Checksum:ⁱE56F74332AF8D2DE

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	142	L → P in BAB15436 (PubMed:14702039).Curated		1
Sequence conflictⁱ	267	F → L in BAC87534 (PubMed:14702039).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_027390	9	M → V1 PublicationCorresponds to variant dbSNP:rs554202Ensembl.	1
Natural variantⁱVAR_048857	196	P → H. Corresponds to variant dbSNP:rs34582952Ensembl.	1
Natural variantⁱVAR_027391	313	C → Y. Corresponds to variant dbSNP:rs12281468Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_020358	1 – 82	Missing in isoform 2. 1 PublicationAdd BLAST	82
Alternative sequenceⁱVSP_020359	218 – 284	APLVP…ITTVV → YQASGKSTLGSVGNWQGFYF GGKMAETNADSILVEIFSPF TIKIIFWCLMPKYLEKFPQR RLSDLRN in isoform 3. 1 PublicationAdd BLAST	67
Alternative sequenceⁱVSP_020360	285 – 334	Missing in isoform 3. 1 PublicationAdd BLAST	50

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY157608 mRNA Translation: AAO23672.1 AK026297 mRNA Translation: BAB15436.1 AK128620 mRNA Translation: BAC87534.1 AK291998 mRNA Translation: BAF84687.1 CH471076 Genomic DNA Translation: EAW74983.1 BC103876 mRNA Translation: AAI03877.1 BC103877 mRNA Translation: AAI03878.1 BC103878 mRNA Translation: AAI03879.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS8240.1 [Q3SYC2-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_079374.2, NM_025098.3 [Q3SYC2-1]
UniGeneⁱ	Hs.288568

Genome annotation databases

Ensemblⁱ	ENST00000198801; ENSP00000198801; ENSG00000166391 [Q3SYC2-1] ENST00000525093; ENSP00000436537; ENSG00000166391 [Q3SYC2-3] ENST00000526712; ENSP00000436283; ENSG00000166391 [Q3SYC2-2]
GeneIDⁱ	80168
KEGGⁱ	hsa:80168
UCSC genome browser More...UCSCⁱ	uc010rru.3 human [Q3SYC2-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
Q3SYC2	Monoacylglycerol O-acyltransferase 2		PANTR		252
Q3SYC2-2				252

Protein	Similar proteins		Species	Score	Length
Q3SYC2	Monoacylglycerol O-acyltransferase 2		PANTR		252
Monoacylglycerol O-acyltransferase 2		MACFA		334
Uncharacterized protein		MACMU		334
Monoacylglycerol O-acyltransferase 2		CERAT		334
Monoacylglycerol O-acyltransferase 2		MACNE		334
+21
Q3SYC2-3	MOGAT2 isoform 4		PONAB		284
MOGAT2 isoform 2		PANTR		284

Protein	Similar proteins		Species	Score	Length
Q3SYC2	Monoacylglycerol O-acyltransferase 2		PANTR		252
Monoacylglycerol O-acyltransferase 2		Cebus capucinus imitator		334
Monoacylglycerol O-acyltransferase 2		MACFA		334
Uncharacterized protein		MACMU		334
Monoacylglycerol O-acyltransferase 2		CERAT		334
+339
Q3SYC2-3	MOGAT2 isoform 4		PONAB		284
MOGAT2 isoform 2		PANTR		284
UPI000B4EB558		MERUN		297
UPI00081320F3		MANJA		334
UPI000B4F1164		ONCMY		286
+17

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY157608 mRNA Translation: AAO23672.1 AK026297 mRNA Translation: BAB15436.1 AK128620 mRNA Translation: BAC87534.1 AK291998 mRNA Translation: BAF84687.1 CH471076 Genomic DNA Translation: EAW74983.1 BC103876 mRNA Translation: AAI03877.1 BC103877 mRNA Translation: AAI03878.1 BC103878 mRNA Translation: AAI03879.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS8240.1 [Q3SYC2-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_079374.2, NM_025098.3 [Q3SYC2-1]
UniGeneⁱ	Hs.288568

3D structure databases

ProteinModelPortalⁱ	Q3SYC2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	123154, 2 interactors
STRINGⁱ	9606.ENSP00000198801

Chemistry databases

BindingDBⁱ	Q3SYC2
ChEMBLⁱ	CHEMBL2439944
SwissLipidsⁱ	SLP:000000299

PTM databases

iPTMnetⁱ	Q3SYC2
PhosphoSitePlusⁱ	Q3SYC2

Polymorphism and mutation databases

BioMutaⁱ	MOGAT2
DMDMⁱ	114150036

Proteomic databases

PaxDbⁱ	Q3SYC2
PeptideAtlas More...PeptideAtlasⁱ	Q3SYC2
PRIDEⁱ	Q3SYC2
ProteomicsDBⁱ	61855 61856 [Q3SYC2-2] 61857 [Q3SYC2-3]

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000198801; ENSP00000198801; ENSG00000166391 [Q3SYC2-1] ENST00000525093; ENSP00000436537; ENSG00000166391 [Q3SYC2-3] ENST00000526712; ENSP00000436283; ENSG00000166391 [Q3SYC2-2]
GeneIDⁱ	80168
KEGGⁱ	hsa:80168
UCSC genome browser More...UCSCⁱ	uc010rru.3 human [Q3SYC2-1]

Organism-specific databases

CTDⁱ	80168
DisGeNET More...DisGeNETⁱ	80168
EuPathDBⁱ	HostDB:ENSG00000166391.14
GeneCardsⁱ	MOGAT2
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:23248 MOGAT2
Human Protein Atlas More...HPAⁱ	HPA028834
MIMⁱ	610270 gene
neXtProtⁱ	NX_Q3SYC2
Open Targets More...OpenTargetsⁱ	ENSG00000166391
PharmGKBⁱ	PA134936582
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0831 Eukaryota ENOG410XTG3 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00750000117391
HOGENOMⁱ	HOG000179738
HOVERGENⁱ	HBG065791
InParanoidⁱ	Q3SYC2
KEGG Orthology (KO) More...KOⁱ	K14457
OMAⁱ	RLGFIKI
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0BGQ
PhylomeDBⁱ	Q3SYC2
TreeFamⁱ	TF314707

Enzyme and pathway databases

UniPathwayⁱ	UPA00282
BRENDAⁱ	2.3.1.22 2681
Reactomeⁱ	R-HSA-75109 Triglyceride biosynthesis

Miscellaneous databases

ChiTaRSⁱ	MOGAT2 human
GeneWikiⁱ	MOGAT2
GenomeRNAiⁱ	80168
Protein Ontology More...PROⁱ	PR:Q3SYC2
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000166391
CleanExⁱ	HS_MOGAT2
Genevisibleⁱ	Q3SYC2 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR007130 DAGAT
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03982 DAGAT, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	MOGT2_HUMAN
Accessionⁱ	Q3SYC2Primary (citable) accession number: Q3SYC2 Secondary accession number(s): A8K7I3 , Q3SYC1, Q6ZQZ2, Q86UH6, Q9H630
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	September 5, 2006
	Last sequence update:	September 5, 2006
	Last modified:	June 20, 2018
	This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PATHWAY comments
Index of metabolic and biosynthesis pathways
SIMILARITY comments
Index of protein domains and families

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UniProtKB - Q3SYC2 (MOGT2_HUMAN)

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2-acylglycerol O-acyltransferase 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the ‘Function’ section describes an enzyme regulatory mechanism and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/enzyme_regulation' target='_top'>More...</a></p>Enzyme regulationi

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: triacylglycerol biosynthesis

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Chemistry databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Endoplasmic reticulum

Endoplasmic reticulum

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

Enzyme regulationⁱ

Kineticsⁱ

Pathwayⁱ: triacylglycerol biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ