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UniProtKB - Q3SYC2 (MOGT2_HUMAN)

Protein

2-acylglycerol O-acyltransferase 2

Gene

MOGAT2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by oleic acid and sphingosine, while it is stimulated by phosphatidylcholine, phosphatidylserine and phosphatidic acid.By similarity

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=45 µM for sn-1-monooleoylglycerol1 Publication

    <p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: triacylglycerol biosynthesis

    This protein is involved in the pathway triacylglycerol biosynthesis, which is part of Glycerolipid metabolism.1 Publication
    View all proteins of this organism that are known to be involved in the pathway triacylglycerol biosynthesis and in Glycerolipid metabolism.

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    • 2-acylglycerol O-acyltransferase activity Source: UniProtKB
    • acetyltransferase activity Source: Ensembl
    View the complete GO annotation on QuickGO ...

    GO - Biological processi

    View the complete GO annotation on QuickGO ...

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionAcyltransferase, Transferase
    Biological processGlycerol metabolism, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BRENDA Comprehensive Enzyme Information System

    More...    BRENDAi    		2.3.1.22 2681

    Reactome - a knowledgebase of biological pathways and processes

    More...    Reactomei    		R-HSA-75109 Triglyceride biosynthesis

    UniPathway: a resource for the exploration and annotation of metabolic pathways

    More...    UniPathwayi
    UPA00282

    Chemistry databases

    SwissLipids knowledge resource for lipid biology

    More...    SwissLipidsi    		SLP:000000299

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    2-acylglycerol O-acyltransferase 2 (EC:2.3.1.222 Publications)
    Alternative name(s):
    Acyl-CoA:monoacylglycerol acyltransferase 2
    Short name:
    MGAT2
    Short name:
    hMGAT2
    Diacylglycerol O-acyltransferase candidate 5
    Short name:
    hDC5
    Diacylglycerol acyltransferase 2-like protein 5
    Monoacylglycerol O-acyltransferase 2
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:MOGAT2
    Synonyms:DC5, DGAT2L5
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

    Organism-specific databases

    Eukaryotic Pathogen Database Resources

    More...    EuPathDBi    		HostDB:ENSG00000166391.14

    Human Gene Nomenclature Database

    More...    HGNCi    		HGNC:23248 MOGAT2

    Online Mendelian Inheritance in Man (OMIM)

    More...    MIMi    		610270 gene

    neXtProt; the human protein knowledge platform

    More...    neXtProti    		NX_Q3SYC2

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei23 – 37HelicalSequence analysisAdd BLAST15
    Transmembranei38 – 59HelicalSequence analysisAdd BLAST22
    Transmembranei103 – 123HelicalSequence analysisAdd BLAST21

    Keywords - Cellular componenti

    Cytoplasm, Endoplasmic reticulum, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Organism-specific databases

    DisGeNET

    More...    DisGeNETi    		80168

    Open Targets

    More...    OpenTargetsi    		ENSG00000166391

    The Pharmacogenetics and Pharmacogenomics Knowledge Base

    More...    PharmGKBi    		PA134936582

    Chemistry databases

    ChEMBL database of bioactive drug-like small molecules

    More...    ChEMBLi    		CHEMBL2439944

    Polymorphism and mutation databases

    BioMuta curated single-nucleotide variation and disease association database

    More...    BioMutai    		MOGAT2

    Domain mapping of disease mutations (DMDM)

    More...    DMDMi    		114150036

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002490621 – 3342-acylglycerol O-acyltransferase 2Add BLAST334

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...    PaxDbi    		Q3SYC2

    PeptideAtlas

    More...    PeptideAtlasi    		Q3SYC2

    PRoteomics IDEntifications database

    More...    PRIDEi    		Q3SYC2

    ProteomicsDB human proteome resource

    More...    ProteomicsDBi    		61855
    61856 [Q3SYC2-2]
    61857 [Q3SYC2-3]

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...    iPTMneti    		Q3SYC2

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...    PhosphoSitePlusi    		Q3SYC2

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Highly expressed in liver, small intestine, colon, stomach and kidney.2 Publications

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...    Bgeei    		ENSG00000166391 Expressed in 61 organ(s), highest expression level in right lobe of liver

    CleanEx database of gene expression profiles

    More...    CleanExi    		HS_MOGAT2

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...    Genevisiblei    		Q3SYC2 HS

    Organism-specific databases

    Human Protein Atlas

    More...    HPAi    		HPA028834

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...    BioGridi    		123154, 2 interactors

    STRING: functional protein association networks

    More...    STRINGi    		9606.ENSP00000198801

    Chemistry databases

    BindingDB database of measured binding affinities

    More...    BindingDBi    		Q3SYC2

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

    More...    ProteinModelPortali    		Q3SYC2

    Database of comparative protein structure models

    More...    ModBasei    		Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...    MobiDBi    		Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the diacylglycerol acyltransferase family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...    eggNOGi    		KOG0831 Eukaryota
    ENOG410XTG3 LUCA

    Ensembl GeneTree

    More...    GeneTreei    		ENSGT00940000153475

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...    HOGENOMi    		HOG000179738

    The HOVERGEN Database of Homologous Vertebrate Genes

    More...    HOVERGENi    		HBG065791

    InParanoid: Eukaryotic Ortholog Groups

    More...    InParanoidi    		Q3SYC2

    KEGG Orthology (KO)

    More...    KOi    		K14457

    Identification of Orthologs from Complete Genome Data

    More...    OMAi    		RLGFIKI

    Database of Orthologous Groups

    More...    OrthoDBi    		EOG091G0BGQ

    Database for complete collections of gene phylogenies

    More...    PhylomeDBi    		Q3SYC2

    TreeFam database of animal gene trees

    More...    TreeFami    		TF314707

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...    InterProi    		View protein in InterPro
    IPR007130 DAGAT

    Pfam protein domain database

    More...    Pfami    		View protein in Pfam
    PF03982 DAGAT, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
    Isoform 1 (identifier: Q3SYC2-1) [UniParc]FASTAAdd to basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide
            10         20         30         40         50
    MVEFAPLFMP WERRLQTLAV LQFVFSFLAL AEICTVGFIA LLFTRFWLLT 
            60         70         80         90        100
    VLYAAWWYLD RDKPRQGGRH IQAIRCWTIW KYMKDYFPIS LVKTAELDPS 
           110        120        130        140        150
    RNYIAGFHPH GVLAVGAFAN LCTESTGFSS IFPGIRPHLM MLTLWFRAPF 
           160        170        180        190        200
    FRDYIMSAGL VTSEKESAAH ILNRKGGGNL LGIIVGGAQE ALDARPGSFT 
           210        220        230        240        250
    LLLRNRKGFV RLALTHGAPL VPIFSFGEND LFDQIPNSSG SWLRYIQNRL 
           260        270        280        290        300
    QKIMGISLPL FHGRGVFQYS FGLIPYRRPI TTVVGKPIEV QKTLHPSEEE 
           310        320        330 
    VNQLHQRYIK ELCNLFEAHK LKFNIPADQH LEFC
    Length:334
    Mass (Da):38,196
    Last modified:September 5, 2006 - v2
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i57C4A964BAFA76BD
    GO
    Isoform 2 (identifier: Q3SYC2-2) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-82: Missing.

    Note: No experimental confirmation available.
    Show »
    Length:252
    Mass (Da):28,283
    Checksum:i902B6B67B2E8CC02
    GO
    Isoform 3 (identifier: Q3SYC2-3) [UniParc]FASTAAdd to basket
    Also known as: MGAT2V, Trunc

    The sequence of this isoform differs from the canonical sequence as follows:
         218-284: APLVPIFSFG...PYRRPITTVV → YQASGKSTLG...PQRRLSDLRN
         285-334: Missing.

    Show »
    Length:284
    Mass (Da):32,298
    Checksum:iE56F74332AF8D2DE
    GO

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti142L → P in BAB15436 (PubMed:14702039).Curated1
    Sequence conflicti267F → L in BAC87534 (PubMed:14702039).Curated1

    Natural variant

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0273909M → V1 PublicationCorresponds to variant dbSNP:rs554202Ensembl.1
    Natural variantiVAR_048857196P → H. Corresponds to variant dbSNP:rs34582952Ensembl.1
    Natural variantiVAR_027391313C → Y. Corresponds to variant dbSNP:rs12281468Ensembl.1

    Alternative sequence

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0203581 – 82Missing in isoform 2. 1 PublicationAdd BLAST82
    Alternative sequenceiVSP_020359218 – 284APLVP…ITTVV → YQASGKSTLGSVGNWQGFYF GGKMAETNADSILVEIFSPF TIKIIFWCLMPKYLEKFPQR RLSDLRN in isoform 3. 1 PublicationAdd BLAST67
    Alternative sequenceiVSP_020360285 – 334Missing in isoform 3. 1 PublicationAdd BLAST50

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...    EMBLi

    GenBank nucleotide sequence database

    More...    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...    DDBJi
    Links Updated
    		AY157608 mRNA Translation: AAO23672.1
    AK026297 mRNA Translation: BAB15436.1
    AK128620 mRNA Translation: BAC87534.1
    AK291998 mRNA Translation: BAF84687.1
    CH471076 Genomic DNA Translation: EAW74983.1
    BC103876 mRNA Translation: AAI03877.1
    BC103877 mRNA Translation: AAI03878.1
    BC103878 mRNA Translation: AAI03879.1

    The Consensus CDS (CCDS) project

    More...    CCDSi    		CCDS8240.1 [Q3SYC2-1]

    NCBI Reference Sequences

    More...    RefSeqi    		NP_079374.2, NM_025098.3 [Q3SYC2-1]

    UniGene gene-oriented nucleotide sequence clusters

    More...    UniGenei    		Hs.288568

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...    Ensembli    		ENST00000198801; ENSP00000198801; ENSG00000166391 [Q3SYC2-1]
    ENST00000525093; ENSP00000436537; ENSG00000166391 [Q3SYC2-3]
    ENST00000526712; ENSP00000436283; ENSG00000166391 [Q3SYC2-2]

    Database of genes from NCBI RefSeq genomes

    More...    GeneIDi    		80168

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...    KEGGi    		hsa:80168

    UCSC genome browser

    More...    UCSCi    		uc010rru.3 human [Q3SYC2-1]

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    		AY157608 mRNA Translation: AAO23672.1
    AK026297 mRNA Translation: BAB15436.1
    AK128620 mRNA Translation: BAC87534.1
    AK291998 mRNA Translation: BAF84687.1
    CH471076 Genomic DNA Translation: EAW74983.1
    BC103876 mRNA Translation: AAI03877.1
    BC103877 mRNA Translation: AAI03878.1
    BC103878 mRNA Translation: AAI03879.1
    CCDSiCCDS8240.1 [Q3SYC2-1]
    RefSeqiNP_079374.2, NM_025098.3 [Q3SYC2-1]
    UniGeneiHs.288568

    3D structure databases

    ProteinModelPortaliQ3SYC2
    ModBaseiSearch...
    MobiDBiSearch...

    Protein-protein interaction databases

    BioGridi123154, 2 interactors
    STRINGi9606.ENSP00000198801

    Chemistry databases

    BindingDBiQ3SYC2
    ChEMBLiCHEMBL2439944
    SwissLipidsiSLP:000000299

    PTM databases

    iPTMnetiQ3SYC2
    PhosphoSitePlusiQ3SYC2

    Polymorphism and mutation databases

    BioMutaiMOGAT2
    DMDMi114150036

    Proteomic databases

    PaxDbiQ3SYC2
    PeptideAtlasiQ3SYC2
    PRIDEiQ3SYC2
    ProteomicsDBi61855
    61856 [Q3SYC2-2]
    61857 [Q3SYC2-3]

    Protocols and materials databases

    Structural Biology KnowledgebaseSearch...

    Genome annotation databases

    EnsembliENST00000198801; ENSP00000198801; ENSG00000166391 [Q3SYC2-1]
    ENST00000525093; ENSP00000436537; ENSG00000166391 [Q3SYC2-3]
    ENST00000526712; ENSP00000436283; ENSG00000166391 [Q3SYC2-2]
    GeneIDi80168
    KEGGihsa:80168
    UCSCiuc010rru.3 human [Q3SYC2-1]

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...    CTDi    		80168
    DisGeNETi80168
    EuPathDBiHostDB:ENSG00000166391.14

    GeneCards: human genes, protein and diseases

    More...    GeneCardsi    		MOGAT2
    HGNCiHGNC:23248 MOGAT2
    HPAiHPA028834
    MIMi610270 gene
    neXtProtiNX_Q3SYC2
    OpenTargetsiENSG00000166391
    PharmGKBiPA134936582

    GenAtlas: human gene database

    More...    GenAtlasi    		Search...

    Phylogenomic databases

    eggNOGiKOG0831 Eukaryota
    ENOG410XTG3 LUCA
    GeneTreeiENSGT00940000153475
    HOGENOMiHOG000179738
    HOVERGENiHBG065791
    InParanoidiQ3SYC2
    KOiK14457
    OMAiRLGFIKI
    OrthoDBiEOG091G0BGQ
    PhylomeDBiQ3SYC2
    TreeFamiTF314707

    Enzyme and pathway databases

    UniPathwayi
    UPA00282

    BRENDAi2.3.1.22 2681
    ReactomeiR-HSA-75109 Triglyceride biosynthesis

    Miscellaneous databases

    ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

    More...    ChiTaRSi    		MOGAT2 human

    The Gene Wiki collection of pages on human genes and proteins

    More...    GeneWikii    		MOGAT2

    Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

    More...    GenomeRNAii    		80168

    Protein Ontology

    More...    PROi    		PR:Q3SYC2

    The Stanford Online Universal Resource for Clones and ESTs

    More...    SOURCEi    		Search...

    Gene expression databases

    BgeeiENSG00000166391 Expressed in 61 organ(s), highest expression level in right lobe of liver
    CleanExiHS_MOGAT2
    GenevisibleiQ3SYC2 HS

    Family and domain databases

    InterProiView protein in InterPro
    IPR007130 DAGAT
    PfamiView protein in Pfam
    PF03982 DAGAT, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...    ProtoNeti    		Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMOGT2_HUMAN
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3SYC2
    Secondary accession number(s): A8K7I3
    , Q3SYC1, Q6ZQZ2, Q86UH6, Q9H630
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
    Last sequence update: September 5, 2006
    Last modified: December 5, 2018
    This is version 103 of the entry and version 2 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Human chromosome 11
      Human chromosome 11: entries, gene names and cross-references to MIM
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    5. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    6. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    UniProt is an ELIXIR core data resource
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