UniProtKB - Q3SX64 (OD3L2_HUMAN)
Protein
Outer dense fiber protein 3-like protein 2
Gene
ODF3L2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Outer dense fiber protein 3-like protein 2 |
Gene namesi | Name:ODF3L2 Synonyms:C19orf19 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:26841, ODF3L2 |
neXtProti | NX_Q3SX64 |
VEuPathDBi | HostDB:ENSG00000181781.9 |
Subcellular locationi
Cytoskeleton
- cytoplasmic microtubule Source: UniProtKB
- cytoskeleton Source: GO_Central
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000181781 |
PharmGKBi | PA162398387 |
Miscellaneous databases
Pharosi | Q3SX64, Tdark |
Genetic variation databases
BioMutai | ODF3L2 |
DMDMi | 125888011 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000274520 | 1 – 289 | Outer dense fiber protein 3-like protein 2Add BLAST | 289 |
Proteomic databases
MassIVEi | Q3SX64 |
PaxDbi | Q3SX64 |
PeptideAtlasi | Q3SX64 |
PRIDEi | Q3SX64 |
ProteomicsDBi | 61814 [Q3SX64-1] 61815 [Q3SX64-2] |
PTM databases
iPTMneti | Q3SX64 |
PhosphoSitePlusi | Q3SX64 |
Expressioni
Gene expression databases
Bgeei | ENSG00000181781, Expressed in right testis and 90 other tissues |
Genevisiblei | Q3SX64, HS |
Organism-specific databases
HPAi | ENSG00000181781, Group enriched (skeletal muscle, testis) |
Interactioni
Binary interactionsi
Hide detailsQ3SX64
Protein-protein interaction databases
BioGRIDi | 129881, 11 interactors |
IntActi | Q3SX64, 17 interactors |
STRINGi | 9606.ENSP00000318029 |
Miscellaneous databases
RNActi | Q3SX64, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 122 – 148 | STPGR 1Add BLAST | 27 | |
Repeati | 202 – 227 | STPGR 2Add BLAST | 26 | |
Repeati | 238 – 263 | STPGR 3Add BLAST | 26 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 118 – 245 | Pro-richAdd BLAST | 128 |
Sequence similaritiesi
Belongs to the ODF3 family.Curated
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | ENOG502QRKE, Eukaryota |
GeneTreei | ENSGT00940000160480 |
HOGENOMi | CLU_088282_1_0_1 |
InParanoidi | Q3SX64 |
OMAi | YVNHDCT |
OrthoDBi | 920847at2759 |
PhylomeDBi | Q3SX64 |
TreeFami | TF325804 |
Family and domain databases
InterProi | View protein in InterPro IPR010736, SHIPPO-rpt |
Pfami | View protein in Pfam PF07004, SHIPPO-rpt, 3 hits |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: Q3SX64-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MGTLSCDSTP RLATAPLGRR VTEGQIPETG LRKSCGTATL ENGSGPGLYV
60 70 80 90 100
LPSTVGFINH DCTRVASPAY SLVRRPSEAP PQDTSPGPIY FLDPKVTRFG
110 120 130 140 150
RSCTPAYSMQ GRAKSRGPEV TPGPGAYSPE KVPPVRHRTP PAFTLGCRLP
160 170 180 190 200
LKPLDTSAPA PNAYTMPPLW GSQIFTKPSS PSYTVVGRTP PARPPQDPAE
210 220 230 240 250
IPGPGQYDSP DANTYRQRLP AFTMLGRPRA PRPLEETPGP GAHCPEQVTV
260 270 280
NKARAPAFSM GIRHSKRAST MAATTPSRPA GHRLPGRCC
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_053951 | 135 | V → A1 PublicationCorresponds to variant dbSNP:rs34551779Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_022778 | 43 – 78 | Missing in isoform 2. 1 PublicationAdd BLAST | 36 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK097378 mRNA Translation: BAC05028.1 BC104468 mRNA Translation: AAI04469.1 BC104469 mRNA Translation: AAI04470.1 |
CCDSi | CCDS12027.1 [Q3SX64-1] |
RefSeqi | NP_872383.1, NM_182577.2 [Q3SX64-1] |
Genome annotation databases
Ensembli | ENST00000315489; ENSP00000318029; ENSG00000181781 [Q3SX64-1] ENST00000382696; ENSP00000372143; ENSG00000181781 [Q3SX64-2] |
GeneIDi | 284451 |
KEGGi | hsa:284451 |
UCSCi | uc002lor.3, human [Q3SX64-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK097378 mRNA Translation: BAC05028.1 BC104468 mRNA Translation: AAI04469.1 BC104469 mRNA Translation: AAI04470.1 |
CCDSi | CCDS12027.1 [Q3SX64-1] |
RefSeqi | NP_872383.1, NM_182577.2 [Q3SX64-1] |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 129881, 11 interactors |
IntActi | Q3SX64, 17 interactors |
STRINGi | 9606.ENSP00000318029 |
PTM databases
iPTMneti | Q3SX64 |
PhosphoSitePlusi | Q3SX64 |
Genetic variation databases
BioMutai | ODF3L2 |
DMDMi | 125888011 |
Proteomic databases
MassIVEi | Q3SX64 |
PaxDbi | Q3SX64 |
PeptideAtlasi | Q3SX64 |
PRIDEi | Q3SX64 |
ProteomicsDBi | 61814 [Q3SX64-1] 61815 [Q3SX64-2] |
Protocols and materials databases
Antibodypediai | 67090, 32 antibodies |
Genome annotation databases
Ensembli | ENST00000315489; ENSP00000318029; ENSG00000181781 [Q3SX64-1] ENST00000382696; ENSP00000372143; ENSG00000181781 [Q3SX64-2] |
GeneIDi | 284451 |
KEGGi | hsa:284451 |
UCSCi | uc002lor.3, human [Q3SX64-1] |
Organism-specific databases
CTDi | 284451 |
GeneCardsi | ODF3L2 |
HGNCi | HGNC:26841, ODF3L2 |
HPAi | ENSG00000181781, Group enriched (skeletal muscle, testis) |
neXtProti | NX_Q3SX64 |
OpenTargetsi | ENSG00000181781 |
PharmGKBi | PA162398387 |
VEuPathDBi | HostDB:ENSG00000181781.9 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QRKE, Eukaryota |
GeneTreei | ENSGT00940000160480 |
HOGENOMi | CLU_088282_1_0_1 |
InParanoidi | Q3SX64 |
OMAi | YVNHDCT |
OrthoDBi | 920847at2759 |
PhylomeDBi | Q3SX64 |
TreeFami | TF325804 |
Enzyme and pathway databases
PathwayCommonsi | Q3SX64 |
Miscellaneous databases
BioGRID-ORCSi | 284451, 3 hits in 873 CRISPR screens |
GenomeRNAii | 284451 |
Pharosi | Q3SX64, Tdark |
PROi | PR:Q3SX64 |
RNActi | Q3SX64, protein |
Gene expression databases
Bgeei | ENSG00000181781, Expressed in right testis and 90 other tissues |
Genevisiblei | Q3SX64, HS |
Family and domain databases
InterProi | View protein in InterPro IPR010736, SHIPPO-rpt |
Pfami | View protein in Pfam PF07004, SHIPPO-rpt, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | OD3L2_HUMAN | |
Accessioni | Q3SX64Primary (citable) accession number: Q3SX64 Secondary accession number(s): Q3SX65, Q8N1L2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 6, 2007 |
Last sequence update: | February 6, 2007 | |
Last modified: | February 10, 2021 | |
This is version 104 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 19
Human chromosome 19: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - SIMILARITY comments
Index of protein domains and families