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UniProtKB - Q3MIX3 (ADCK5_HUMAN)

Entry version 131 (23 Feb 2022)
Sequence version 3 (12 Sep 2018)
Previous versions | rss
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Protein

Uncharacterized aarF domain-containing protein kinase 5

Gene

ADCK5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q3MIX3

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q3MIX3

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q3MIX3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized aarF domain-containing protein kinase 5 (EC:2.7.11.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ADCK5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:21738, ADCK5

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q3MIX3

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000173137

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei50 – 67HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000173137

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134963849

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q3MIX3, Tdark

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL4105886

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ADCK5

Domain mapping of disease mutations (DMDM)

More...DMDMi		121958055

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002718001 – 580Uncharacterized aarF domain-containing protein kinase 5Add BLAST580

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q3MIX3

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q3MIX3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q3MIX3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q3MIX3

PeptideAtlas

More...PeptideAtlasi		Q3MIX3

PRoteomics IDEntifications database

More...PRIDEi		Q3MIX3

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		61799

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q3MIX3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q3MIX3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000173137, Expressed in mucosa of transverse colon and 137 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q3MIX3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q3MIX3, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000173137, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		128442, 17 interactors

Protein interaction database and analysis system

More...IntActi		Q3MIX3, 31 interactors

Molecular INTeraction database

More...MINTi		Q3MIX3

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000310547

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q3MIX3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q3MIX3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini179 – 419Protein kinaseAdd BLAST241

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein kinase superfamily. ADCK protein kinase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1235, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159821

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_006533_2_6_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q3MIX3

Identification of Orthologs from Complete Genome Data

More...OMAi		RPWRGGW

Database of Orthologous Groups

More...OrthoDBi		790106at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q3MIX3

TreeFam database of animal gene trees

More...TreeFami		TF354300

Family and domain databases

Conserved Domains Database

More...CDDi		cd13969, ADCK1-like, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004147, ABC1_dom
IPR045307, ADCK1_dom
IPR011009, Kinase-like_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03109, ABC1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF56112, SSF56112, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q3MIX3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWRPVQLCHF HSALLHSRQK PWPSPAVFFR RNVRGLPPRF SSPTPLWRKV 
        60         70         80         90        100
LSTAVVGAPL LLGARYVMAE AREKRRMRLV VDGMGRFGRS LKVGLQISLD 
       110        120        130        140        150
YWWCTNVVLR GVEENSPGYL EVMSACHQRA ADALVAGAIS NGGLYVKLGQ 
       160        170        180        190        200
GLCSFNHLLP PEYTRTLRVL EDRALKRGFQ EVDELFLEDF QALPHELFQE 
       210        220        230        240        250
FDYQPIAAAS LAQVHRAKLH DGTSVAVKVQ YIDLRDRFDG DIHTLELLLR 
       260        270        280        290        300
LVEVMHPSFG FSWVLQDLKG TLAQELDFEN EGRNAERCAR ELAHFPYVVV 
       310        320        330        340        350
PRVHWDKSSK RVLTADFCAG CKVNDVEAIR SQGLAVHDIA EKLIKAFAEQ 
       360        370        380        390        400
IFYTGFIHSD PHPGNVLVRK GPDGKAELVL LDHGLYQFLE EKDRAALCQL 
       410        420        430        440        450
WRAIILRDDA AMRAHAAALG VQDYLLFAEM LMQRPVRLGQ LWGSHLLSRE 
       460        470        480        490        500
EAAYMVDMAR ERFEAVMAVL RELPRPMLLV LRNINTVRAI NVALGAPVDR 
       510        520        530        540        550
YFLMAKRAVR GWSRLAGATY RGVYGTSLLR HAKVVWEMLK FEVALRLETL 
       560        570        580
AMRLTALLAR ALVHLSLVPP AEELYQYLET
Length:580
Mass (Da):65,828
Last modified:September 12, 2018 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iACA0DB28B7B16F0C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PLF3E9PLF3_HUMAN
Uncharacterized aarF domain-contain...
ADCK5
115Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PJ20E9PJ20_HUMAN
Uncharacterized aarF domain-contain...
ADCK5
129Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
R4GN53R4GN53_HUMAN
Uncharacterized aarF domain-contain...
ADCK5
87Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH31570 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti275E → G in BAG52608 (PubMed:14702039).Curated1
Sequence conflicti283R → G in AAH85013 (PubMed:15489334).Curated1
Sequence conflicti324 – 338NDVEA…LAVHD → GGLVLCPLQCLSSPQ in AAH64345 (PubMed:15489334).CuratedAdd BLAST15

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02999617S → R1 PublicationCorresponds to variant dbSNP:rs6599528Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK092773 mRNA Translation: BAG52608.1
AC233992 Genomic DNA No translation available.
BC031570 mRNA Translation: AAH31570.1 Different initiation.
BC064345 mRNA Translation: AAH64345.1
BC085013 mRNA Translation: AAH85013.1
BC101659 mRNA Translation: AAI01660.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS34965.2

NCBI Reference Sequences

More...RefSeqi		NP_777582.4, NM_174922.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000308860; ENSP00000310547; ENSG00000173137
ENST00000645968; ENSP00000494807; ENSG00000285451

Database of genes from NCBI RefSeq genomes

More...GeneIDi		203054

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:203054

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000308860.11; ENSP00000310547.6; NM_174922.5; NP_777582.4

UCSC genome browser

More...UCSCi		uc003zch.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK092773 mRNA Translation: BAG52608.1
AC233992 Genomic DNA No translation available.
BC031570 mRNA Translation: AAH31570.1 Different initiation.
BC064345 mRNA Translation: AAH64345.1
BC085013 mRNA Translation: AAH85013.1
BC101659 mRNA Translation: AAI01660.1
CCDSiCCDS34965.2
RefSeqiNP_777582.4, NM_174922.4

3D structure databases

SMRiQ3MIX3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi128442, 17 interactors
IntActiQ3MIX3, 31 interactors
MINTiQ3MIX3
STRINGi9606.ENSP00000310547

Chemistry databases

ChEMBLiCHEMBL4105886

PTM databases

iPTMnetiQ3MIX3
PhosphoSitePlusiQ3MIX3

Genetic variation databases

BioMutaiADCK5
DMDMi121958055

Proteomic databases

EPDiQ3MIX3
jPOSTiQ3MIX3
MassIVEiQ3MIX3
PaxDbiQ3MIX3
PeptideAtlasiQ3MIX3
PRIDEiQ3MIX3
ProteomicsDBi61799

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		28478, 188 antibodies from 31 providers

The DNASU plasmid repository

More...DNASUi		203054

Genome annotation databases

EnsembliENST00000308860; ENSP00000310547; ENSG00000173137
ENST00000645968; ENSP00000494807; ENSG00000285451
GeneIDi203054
KEGGihsa:203054
MANE-SelectiENST00000308860.11; ENSP00000310547.6; NM_174922.5; NP_777582.4
UCSCiuc003zch.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		203054

GeneCards: human genes, protein and diseases

More...GeneCardsi		ADCK5
HGNCiHGNC:21738, ADCK5
HPAiENSG00000173137, Low tissue specificity
neXtProtiNX_Q3MIX3
OpenTargetsiENSG00000173137
PharmGKBiPA134963849
VEuPathDBiHostDB:ENSG00000173137

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1235, Eukaryota
GeneTreeiENSGT00940000159821
HOGENOMiCLU_006533_2_6_1
InParanoidiQ3MIX3
OMAiRPWRGGW
OrthoDBi790106at2759
PhylomeDBiQ3MIX3
TreeFamiTF354300

Enzyme and pathway databases

PathwayCommonsiQ3MIX3
SignaLinkiQ3MIX3
SIGNORiQ3MIX3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		203054, 8 hits in 1078 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ADCK5, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		203054
PharosiQ3MIX3, Tdark

Protein Ontology

More...PROi		PR:Q3MIX3
RNActiQ3MIX3, protein

Gene expression databases

BgeeiENSG00000173137, Expressed in mucosa of transverse colon and 137 other tissues
ExpressionAtlasiQ3MIX3, baseline and differential
GenevisibleiQ3MIX3, HS

Family and domain databases

CDDicd13969, ADCK1-like, 1 hit
InterProiView protein in InterPro
IPR004147, ABC1_dom
IPR045307, ADCK1_dom
IPR011009, Kinase-like_dom_sf
PfamiView protein in Pfam
PF03109, ABC1, 1 hit
SUPFAMiSSF56112, SSF56112, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiADCK5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3MIX3
Secondary accession number(s): B3KS46
, Q5U4P1, Q6P2S4, Q8N5V3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: September 12, 2018
Last modified: February 23, 2022
This is version 131 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human and mouse protein kinases
    Human and mouse protein kinases: classification and index
  2. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  3. Human entries with genetic variants
    List of human entries with genetic variants
  4. Human variants curated from literature reports
    Index of human variants curated from literature reports
  5. SIMILARITY comments
    Index of protein domains and families
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