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Protein

Xylulose kinase

Gene

Xylb

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.By similarity

Catalytic activityi

ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei99SubstrateBy similarity1
Binding sitei170SubstrateBy similarity1
Binding sitei280SubstrateBy similarity1
Binding sitei281SubstrateBy similarity1
Binding sitei355ATPBy similarity1
Binding sitei445ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi441 – 442ATPBy similarity2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Xylulose kinase (EC:2.7.1.17)
Short name:
Xylulokinase
Gene namesi
Name:Xylb
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1307372 Xylb

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002309881 – 536Xylulose kinaseAdd BLAST536

Proteomic databases

PaxDbiQ3MIF4
PeptideAtlasiQ3MIF4
PRIDEiQ3MIF4

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019106

Structurei

3D structure databases

ProteinModelPortaliQ3MIF4
SMRiQ3MIF4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FGGY kinase family.Curated

Phylogenomic databases

eggNOGiKOG2531 Eukaryota
COG1070 LUCA
HOGENOMiHOG000174850
HOVERGENiHBG053124
InParanoidiQ3MIF4
KOiK00854
PhylomeDBiQ3MIF4

Family and domain databases

InterProiView protein in InterPro
IPR000577 Carb_kinase_FGGY
IPR018485 Carb_kinase_FGGY_C
IPR018484 Carb_kinase_FGGY_N
PfamiView protein in Pfam
PF02782 FGGY_C, 1 hit
PF00370 FGGY_N, 1 hit
PIRSFiPIRSF000538 GlpK, 1 hit

Sequencei

Sequence statusi: Complete.

Q3MIF4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAERAGRRCC LGWDFSTQQV KVVAVDAELN VFYEDSVHFD RDLPEFGTQG
60 70 80 90 100
GVHVHKDRLT VTSPVLMWVQ ALDLILEKMK ASGFDFSQVL ALSGAGQQHG
110 120 130 140 150
SVYWKTGASL ALSSLSPALL LHQQLQACFS VSDCPIWMDS STTAQCHQLE
160 170 180 190 200
AAVGGAQALS CLTGSRAYER FTGNQISKIF QKNPEAYSNS ERISLVSSFA
210 220 230 240 250
ASLFLGRYSP IDYSDGSGMN LLQIQEKVWS QACLDACAPH LKEKLGSPVP
260 270 280 290 300
SCSVVGAISS YYVQRYGFPP GCKVVAFTGD NPASLAGMRL EEGDVAVSLG
310 320 330 340 350
TSDTLFLWLQ KPMPALEGHI FCNPVDARQY MALLCFKNGS LMREKIRDES
360 370 380 390 400
ASCSWNKFSK ALQSTEMGNN GNLGFYFDVM EITPEIIGCH RFNADNMEVS
410 420 430 440 450
AFPGDVEIRA LVEGQFMAKR IHAEGLGYRI MPKTKILATG GASHNKDILQ
460 470 480 490 500
VLADVFGAPV YVIDTTSSAC VGSAYRAFHG LAGGTGVAFS EVVKSAPQPS
510 520 530
LAATPNPGAS QVYAALLPRY AELEQRILSK ARGPLE
Length:536
Mass (Da):57,970
Last modified:October 25, 2005 - v1
Checksum:i39206405B8361CB4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC101852 mRNA Translation: AAI01853.1
RefSeqiNP_001028876.1, NM_001033704.1
UniGeneiRn.8732

Genome annotation databases

GeneIDi316067
KEGGirno:316067
UCSCiRGD:1307372 rat

Similar proteinsi

Entry informationi

Entry nameiXYLB_RAT
AccessioniPrimary (citable) accession number: Q3MIF4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: October 25, 2005
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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