UniProtKB - Q3KRC8 (Q3KRC8_RAT)
Protein
Submitted name:
AT rich interactive domain 5A (Mrf1 like)
Gene
Arid5a
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- androgen receptor binding Source: RGD
- chromatin binding Source: RGD
- estrogen receptor binding Source: RGD
- identical protein binding Source: RGD
- retinoid X receptor binding Source: RGD
- RNA stem-loop binding Source: RGD
- sequence-specific DNA binding Source: RGD
- thyroid hormone receptor binding Source: RGD
- transcription corepressor activity Source: RGD
- transcription factor binding Source: RGD
- transcription regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- cellular response to estrogen stimulus Source: RGD
- cellular response to lipopolysaccharide Source: RGD
- chondrocyte differentiation Source: RGD
- negative regulation of transcription by RNA polymerase II Source: RGD
- positive regulation of histone acetylation Source: RGD
- positive regulation of interferon-gamma production Source: RGD
- positive regulation of interleukin-17 production Source: RGD
- positive regulation of interleukin-6 production Source: RGD
- positive regulation of T-helper 17 type immune response Source: RGD
- positive regulation of T-helper 1 cell cytokine production Source: RGD
- positive regulation of transcription by RNA polymerase II Source: RGD
- positive regulation of tumor necrosis factor secretion Source: RGD
- regulation of transcription by RNA polymerase II Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: AT rich interactive domain 5A (Mrf1 like)ImportedSubmitted name: AT rich interactive domain 5A (Mrf1 like), isoform CRA_bImportedSubmitted name: AT-rich interaction domain 5AImported |
Gene namesi | Name:Arid5aImported ORF Names:rCG_22219Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1311041, Arid5a |
Subcellular locationi
Nucleus
- nucleus Source: RGD
Other locations
- transcription regulator complex Source: RGD
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000015382, Expressed in skeletal muscle tissue and 21 other tissues |
Interactioni
GO - Molecular functioni
- androgen receptor binding Source: RGD
- estrogen receptor binding Source: RGD
- identical protein binding Source: RGD
- retinoid X receptor binding Source: RGD
- thyroid hormone receptor binding Source: RGD
- transcription factor binding Source: RGD
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 68 | DisorderedSequence analysisAdd BLAST | 68 | |
Regioni | 116 – 166 | DisorderedSequence analysisAdd BLAST | 51 | |
Regioni | 262 – 290 | DisorderedSequence analysisAdd BLAST | 29 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 31 | PolyampholyteSequence analysisAdd BLAST | 31 | |
Compositional biasi | 32 – 68 | PolarSequence analysisAdd BLAST | 37 | |
Compositional biasi | 127 – 142 | PolarSequence analysisAdd BLAST | 16 |
Phylogenomic databases
GeneTreei | ENSGT00940000161253 |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q3KRC8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKELRGDDG ATEKLKKAKD SEERQADQTT SEKTKSDAPG QTQLPRQGSS
60 70 80 90 100
RDSTEQLGPV SGSSPPFLGA NSCPEAYKRL LASFYCKGAH GIMSPLAKKK
110 120 130 140 150
LLAQVSKAEA LQCQEEGCRH GARSPNKDLQ ESSQNPRGLA ENSEHQLTPP
160 170 180 190 200
EGLRAPGGST GVEAQVGPCP TAPTFLGRFH AYPTEVLKPV SQHPRDFFSS
210 220 230 240 250
LKDRVLLGPP GKEEGLTAKE SQLVWGGDAN RPSAFHKGST RKRSFYPKPK
260 270 280 290 300
ACWVSPMAKV PAESPGAPLP HPRSPGLSKK RGLEEEGYTH GGKKLKAVSP
310 320 330 340 350
FLKEVDARES EGKPAAPGLA VSCLLGPALG PTPPESYRGT MLRCPLNFTS
360 370 380 390 400
SADPLKGQAS LPFSPLVIPT FPAHLLATTG PSPMATSLMH FPPTPYDTVL
410 420 430
RNRLGPASSA WHVPPVTTYA APHFFHLNTK L
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0G2K0Q5 | A0A0G2K0Q5_RAT | AT rich interactive domain 5A (Mrf1... | Arid5a rCG_22219 | 590 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07067397 Genomic DNA No translation available. BC105777 mRNA Translation: AAI05778.1 CH473965 Genomic DNA Translation: EDL99283.1 |
RefSeqi | NP_001030106.1, NM_001034934.1 XP_017451929.1, XM_017596440.1 XP_017451930.1, XM_017596441.1 |
Genome annotation databases
Ensembli | ENSRNOT00000067688; ENSRNOP00000060873; ENSRNOG00000015382 |
GeneIDi | 316327 |
KEGGi | rno:316327 |
UCSCi | RGD:1311041, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07067397 Genomic DNA No translation available. BC105777 mRNA Translation: AAI05778.1 CH473965 Genomic DNA Translation: EDL99283.1 |
RefSeqi | NP_001030106.1, NM_001034934.1 XP_017451929.1, XM_017596440.1 XP_017451930.1, XM_017596441.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSRNOT00000067688; ENSRNOP00000060873; ENSRNOG00000015382 |
GeneIDi | 316327 |
KEGGi | rno:316327 |
UCSCi | RGD:1311041, rat |
Organism-specific databases
CTDi | 10865 |
RGDi | 1311041, Arid5a |
Phylogenomic databases
GeneTreei | ENSGT00940000161253 |
Gene expression databases
Bgeei | ENSRNOG00000015382, Expressed in skeletal muscle tissue and 21 other tissues |
Family and domain databases
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3KRC8_RAT | |
Accessioni | Q3KRC8Primary (citable) accession number: Q3KRC8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 8, 2005 |
Last sequence update: | November 8, 2005 | |
Last modified: | December 2, 2020 | |
This is version 98 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |