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UniProtKB - Q3KQU3 (MA7D1_HUMAN)

Entry version 133 (07 Apr 2021)
Sequence version 1 (08 Nov 2005)
Previous versions | rss
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Protein

MAP7 domain-containing protein 1

Gene

MAP7D1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q3KQU3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MAP7 domain-containing protein 1
Alternative name(s):
Arginine/proline-rich coiled-coil domain-containing protein 1
Proline/arginine-rich coiled-coil domain-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MAP7D1
Synonyms:KIAA1187, PARCC1, RPRC1
ORF Names:PP2464
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25514, MAP7D1

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q3KQU3

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000116871.15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000116871

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162394970

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q3KQU3, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MAP7D1

Domain mapping of disease mutations (DMDM)

More...DMDMi		121942584

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003068071 – 841MAP7 domain-containing protein 1Add BLAST841

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei47PhosphothreonineCombined sources1
Modified residuei51PhosphothreonineCombined sources1
Modified residuei70PhosphoserineCombined sources1
Modified residuei86PhosphoserineCombined sources1
Modified residuei93PhosphoserineCombined sources1
Modified residuei97PhosphothreonineCombined sources1
Modified residuei113PhosphoserineCombined sources1
Modified residuei116PhosphoserineCombined sources1
Modified residuei118PhosphothreonineCombined sources1
Modified residuei123PhosphoserineCombined sources1
Modified residuei125PhosphoserineCombined sources1
Modified residuei254PhosphoserineCombined sources1
Modified residuei273PhosphoserineCombined sources1
Modified residuei313PhosphoserineCombined sources1
Modified residuei366PhosphoserineCombined sources1
Modified residuei399PhosphoserineCombined sources1
Modified residuei442PhosphoserineCombined sources1
Modified residuei446PhosphoserineCombined sources1
Modified residuei452PhosphoserineCombined sources1
Modified residuei454PhosphoserineCombined sources1
Modified residuei460PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki462Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei479PhosphoserineBy similarity1
Modified residuei496PhosphoserineBy similarity1
Modified residuei544PhosphoserineCombined sources1
Modified residuei548PhosphoserineCombined sources1
Modified residuei552PhosphoserineCombined sources1
Modified residuei554PhosphothreonineCombined sources1
Modified residuei742PhosphoserineCombined sources1
Modified residuei753PhosphoserineCombined sources1
Modified residuei813PhosphothreonineCombined sources1
Modified residuei816PhosphothreonineCombined sources1
Modified residuei834PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q3KQU3

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q3KQU3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q3KQU3

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q3KQU3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q3KQU3

PeptideAtlas

More...PeptideAtlasi		Q3KQU3

PRoteomics IDEntifications database

More...PRIDEi		Q3KQU3

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		61723 [Q3KQU3-1]
61724 [Q3KQU3-2]
61725 [Q3KQU3-3]
61726 [Q3KQU3-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q3KQU3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q3KQU3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000116871, Expressed in quadriceps femoris and 238 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q3KQU3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q3KQU3, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000116871, Tissue enhanced (skeletal)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		120825, 76 interactors

Protein interaction database and analysis system

More...IntActi		Q3KQU3, 71 interactors

Molecular INTeraction database

More...MINTi		Q3KQU3

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000362244

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q3KQU3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q3KQU3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili128 – 222Sequence analysisAdd BLAST95
Coiled coili412 – 441Sequence analysisAdd BLAST30
Coiled coili593 – 721Sequence analysisAdd BLAST129

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi14 – 127Pro-richAdd BLAST114
Compositional biasi467 – 589Pro-richAdd BLAST123

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MAP7 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QPJP, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000182941

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_017315_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q3KQU3

Identification of Orthologs from Complete Genome Data

More...OMAi		QDRKEAT

Database of Orthologous Groups

More...OrthoDBi		738080at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q3KQU3

TreeFam database of animal gene trees

More...TreeFami		TF332273

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR008604, MAP7_fam

Pfam protein domain database

More...Pfami		View protein in Pfam
PF05672, MAP7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q3KQU3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESGPRAELG AGAPPAVVAR TPPEPRPSPE GDPSPPPPPM SALVPDTPPD 
        60         70         80         90        100
TPPAMKNATS SKQLPLEPES PSGQVGPRPA PPQEESPSSE AKSRGPTPPA 
       110        120        130        140        150
MGPRDARPPR RSSQPSPTAV PASDSPPTKQ EVKKAGERHK LAKERREERA 
       160        170        180        190        200
KYLAAKKAVW LEKEEKAKAL REKQLQERRR RLEEQRLKAE QRRAALEERQ 
       210        220        230        240        250
RQKLEKNKER YEAAIQRSVK KTWAEIRQQR WSWAGALHHS SPGHKTSGSR 
       260        270        280        290        300
CSVSAVNLPK HVDSIINKRL SKSSATLWNS PSRNRSLQLS AWESSIVDRL 
       310        320        330        340        350
MTPTLSFLAR SRSAVTLPRN GRDQGRGCDP GRGPTWGRAG ASLARGPQPD 
       360        370        380        390        400
RTHPSAAVPV CPRSASASPL TPCSVTRSVH RCAPAGERGE RRKPNAGGSP 
       410        420        430        440        450
APVRRRPEAS PVQKKEKKDK ERENEKEKSA LARERSLKKR QSLPASPRAR 
       460        470        480        490        500
LSASTASELS PKSKARPSSP STSWHRPASP CPSPGPGHTL PPKPPSPRGT 
       510        520        530        540        550
TASPKGRVRR KEEAKESPSA AGPEDKSQSK RRASNEKESA APASPAPSPA 
       560        570        580        590        600
PSPTPAPPQK EQPPAETPTD AAVLTSPPAP APPVTPSKPM AGTTDREEAT 
       610        620        630        640        650
RLLAEKRRQA REQREREEQE RRLQAERDKR MREEQLAREA EARAEREAEA 
       660        670        680        690        700
RRREEQEARE KAQAEQEEQE RLQKQKEEAE ARSREEAERQ RLEREKHFQQ 
       710        720        730        740        750
QEQERQERRK RLEEIMKRTR KSEVSETKQK QDSKEANANG SSPEPVKAVE 
       760        770        780        790        800
ARSPGLQKEA VQKEEPIPQE PQWSLPSKEL PASLVNGLQP LPAHQENGFS 
       810        820        830        840 
TNGPSGDKSL SRTPETLLPF AEAEAFLKKA VVQSPQVTEV L
Length:841
Mass (Da):92,820
Last modified:November 8, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i47F5931376A931EF
GO
Isoform 2 (identifier: Q3KQU3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     247-283: Missing.
     729-729: Missing.

Show »
Length:803
Mass (Da):88,726
Checksum:i5B8E46883590DF6A
GO
Isoform 3 (identifier: Q3KQU3-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-454: Missing.
     455-459: TASEL → MNGPV
     570-578: Missing.
     729-729: Missing.

Show »
Length:377
Mass (Da):42,105
Checksum:iE220BB255F897F21
GO
Isoform 4 (identifier: Q3KQU3-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     325-356: Missing.
     729-729: Missing.

Show »
Length:808
Mass (Da):89,467
Checksum:iBB3AFDF24FBB8273
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YF21H0YF21_HUMAN
MAP7 domain-containing protein 1
MAP7D1
248Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JIR3C9JIR3_HUMAN
MAP7 domain-containing protein 1
MAP7D1
244Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PLH3E9PLH3_HUMAN
MAP7 domain-containing protein 1
MAP7D1
140Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG17244 differs from that shown. Reason: Frameshift.Curated
The sequence BAA86501 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti207N → S in AAG17244 (PubMed:15498874).Curated1
Sequence conflicti794H → R in BAC04654 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_035312104R → W. Corresponds to variant dbSNP:rs2296266EnsemblClinVar.1
Natural variantiVAR_053970531R → S. Corresponds to variant dbSNP:rs12563354Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0284831 – 454Missing in isoform 3. 1 PublicationAdd BLAST454
Alternative sequenceiVSP_028484247 – 283Missing in isoform 2. 2 PublicationsAdd BLAST37
Alternative sequenceiVSP_028485325 – 356Missing in isoform 4. 1 PublicationAdd BLAST32
Alternative sequenceiVSP_028486455 – 459TASEL → MNGPV in isoform 3. 1 Publication5
Alternative sequenceiVSP_028487570 – 578Missing in isoform 3. 1 Publication9
Alternative sequenceiVSP_028488729Missing in isoform 2, isoform 3 and isoform 4. 4 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB033013 mRNA Translation: BAA86501.2 Different initiation.
AK001212 mRNA Translation: BAA91557.1
AK095939 mRNA Translation: BAC04654.1
CH471059 Genomic DNA Translation: EAX07381.1
CH471059 Genomic DNA Translation: EAX07382.1
BC027334 mRNA Translation: AAH27334.1
BC106053 mRNA Translation: AAI06054.1
AF218002 mRNA Translation: AAG17244.1 Frameshift.
AL136547 mRNA Translation: CAB66482.2
CR457254 mRNA Translation: CAG33535.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS30673.1 [Q3KQU3-1]
CCDS65492.1 [Q3KQU3-4]
CCDS65493.1 [Q3KQU3-2]

NCBI Reference Sequences

More...RefSeqi		NP_001273294.1, NM_001286365.1 [Q3KQU3-2]
NP_001273295.1, NM_001286366.1 [Q3KQU3-4]
NP_060537.3, NM_018067.4 [Q3KQU3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000316156; ENSP00000320228; ENSG00000116871 [Q3KQU3-2]
ENST00000373150; ENSP00000362243; ENSG00000116871 [Q3KQU3-4]
ENST00000373151; ENSP00000362244; ENSG00000116871 [Q3KQU3-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		55700

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:55700

UCSC genome browser

More...UCSCi		uc001bzz.5, human [Q3KQU3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB033013 mRNA Translation: BAA86501.2 Different initiation.
AK001212 mRNA Translation: BAA91557.1
AK095939 mRNA Translation: BAC04654.1
CH471059 Genomic DNA Translation: EAX07381.1
CH471059 Genomic DNA Translation: EAX07382.1
BC027334 mRNA Translation: AAH27334.1
BC106053 mRNA Translation: AAI06054.1
AF218002 mRNA Translation: AAG17244.1 Frameshift.
AL136547 mRNA Translation: CAB66482.2
CR457254 mRNA Translation: CAG33535.1
CCDSiCCDS30673.1 [Q3KQU3-1]
CCDS65492.1 [Q3KQU3-4]
CCDS65493.1 [Q3KQU3-2]
RefSeqiNP_001273294.1, NM_001286365.1 [Q3KQU3-2]
NP_001273295.1, NM_001286366.1 [Q3KQU3-4]
NP_060537.3, NM_018067.4 [Q3KQU3-1]

3D structure databases

SMRiQ3KQU3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120825, 76 interactors
IntActiQ3KQU3, 71 interactors
MINTiQ3KQU3
STRINGi9606.ENSP00000362244

PTM databases

iPTMnetiQ3KQU3
PhosphoSitePlusiQ3KQU3

Genetic variation databases

BioMutaiMAP7D1
DMDMi121942584

Proteomic databases

EPDiQ3KQU3
jPOSTiQ3KQU3
MassIVEiQ3KQU3
MaxQBiQ3KQU3
PaxDbiQ3KQU3
PeptideAtlasiQ3KQU3
PRIDEiQ3KQU3
ProteomicsDBi61723 [Q3KQU3-1]
61724 [Q3KQU3-2]
61725 [Q3KQU3-3]
61726 [Q3KQU3-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		31646, 69 antibodies

Genome annotation databases

EnsembliENST00000316156; ENSP00000320228; ENSG00000116871 [Q3KQU3-2]
ENST00000373150; ENSP00000362243; ENSG00000116871 [Q3KQU3-4]
ENST00000373151; ENSP00000362244; ENSG00000116871 [Q3KQU3-1]
GeneIDi55700
KEGGihsa:55700
UCSCiuc001bzz.5, human [Q3KQU3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		55700

GeneCards: human genes, protein and diseases

More...GeneCardsi		MAP7D1
HGNCiHGNC:25514, MAP7D1
HPAiENSG00000116871, Tissue enhanced (skeletal)
neXtProtiNX_Q3KQU3
OpenTargetsiENSG00000116871
PharmGKBiPA162394970
VEuPathDBiHostDB:ENSG00000116871.15

Human Unidentified Gene-Encoded large proteins database

More...HUGEi		Search...

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QPJP, Eukaryota
GeneTreeiENSGT00950000182941
HOGENOMiCLU_017315_2_0_1
InParanoidiQ3KQU3
OMAiQDRKEAT
OrthoDBi738080at2759
PhylomeDBiQ3KQU3
TreeFamiTF332273

Enzyme and pathway databases

PathwayCommonsiQ3KQU3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		55700, 14 hits in 1003 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		MAP7D1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		55700
PharosiQ3KQU3, Tdark

Protein Ontology

More...PROi		PR:Q3KQU3
RNActiQ3KQU3, protein

Gene expression databases

BgeeiENSG00000116871, Expressed in quadriceps femoris and 238 other tissues
ExpressionAtlasiQ3KQU3, baseline and differential
GenevisibleiQ3KQU3, HS

Family and domain databases

InterProiView protein in InterPro
IPR008604, MAP7_fam
PfamiView protein in Pfam
PF05672, MAP7, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMA7D1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3KQU3
Secondary accession number(s): D3DPS4
, Q7L8J5, Q8N905, Q8TAK0, Q9HBQ2, Q9NW29, Q9ULN3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: November 8, 2005
Last modified: April 7, 2021
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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