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Entry version 66 (26 Feb 2020)
Sequence version 1 (08 Nov 2005)
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Protein
Submitted name:

SciS protein

Gene

sciS

Organism
Burkholderia pseudomallei (strain 1710b)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BPSE320372:G1G58-6368-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
SciS proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sciSImported
Ordered Locus Names:BURPS1710b_A1689Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBurkholderia pseudomallei (strain 1710b)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri320372 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002700 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 35HelicalSequence analysisAdd BLAST24
Transmembranei41 – 62HelicalSequence analysisAdd BLAST22
Transmembranei69 – 92HelicalSequence analysisAdd BLAST24
Transmembranei98 – 117HelicalSequence analysisAdd BLAST20
Transmembranei575 – 594HelicalSequence analysisAdd BLAST20

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini314 – 582ImcF-related_NInterPro annotationAdd BLAST269
Domaini634 – 951IcmF-relatedInterPro annotationAdd BLAST318
Domaini1073 – 1274IcmF_CInterPro annotationAdd BLAST202

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni250 – 270DisorderedSequence analysisAdd BLAST21
Regioni1332 – 1358DisorderedSequence analysisAdd BLAST27

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003353_2_0_4

KEGG Orthology (KO)

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KOi
K11891

Identification of Orthologs from Complete Genome Data

More...
OMAi
FFGYGGT

Database of Orthologous Groups

More...
OrthoDBi
393769at2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009612 IcmF-related
IPR025743 IcmF-related_N_dom
IPR010623 IcmF_C
IPR017731 T6SS_IcmF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06761 IcmF-related, 1 hit
PF06744 IcmF_C, 1 hit
PF14331 ImcF-related_N, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03348 VI_IcmF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q3JHV7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNKFLSFLVS RSFIAFVALL AVALVIWFVG PFVAFGGLTP LAGAGMRVLA
60 70 80 90 100
IALLLAGVLL WLAGRPTSIV FVALLCVLIW HASPLLAFGG ATPFAAEAVR
110 120 130 140 150
AIAIALVLAA FALHLAFRLL QKARTDPDFL KSLLEFGGKQ PESPAAGRLV
160 170 180 190 200
AVNAAIAGAI ARLKGMRSGA RGLRRLLRGK RYLYELPWYV TLGSRACGKT
210 220 230 240 250
SALLNAGLSF PVAAQMPRAA AGLPDHGGSV DWWLTNDAVL IDTAGHYTRH
260 270 280 290 300
GTSAHAAPLP PAGPAPHAQP FDAAADARRA NGQPAGERHA VAMAAAAPSS
310 320 330 340 350
AAFVDERQAQ WRQTVDQAEW LGFLRTLRKH RPREPINGAL LAVDVATLTS
360 370 380 390 400
ADDNARHAEA AALRARLADL RAQLGVRFPV YLIVTKTDQL PGFAEYFSAL
410 420 430 440 450
TTEGRAQTWG FTLPYDKETI ADEGVHARCA DELRALAARL AAGVNTRLQE
460 470 480 490 500
EHDTQRRRRL AALPEEFLVL TRPLGELIDR VFTDSRYDDT QHHATLRGVY
510 520 530 540 550
FTSAAQTGGE AAAETRTVAR RLAAATGRAP AAAARAAQQE TSQSFFLHDL
560 570 580 590 600
LTKIVIPDAR LVQPNLRWEY RSRTLSLAAH ALALLLFAWV AIGLRVSMGN
610 620 630 640 650
NDAYLDALAR KTAALASRVD QLYKAPKPEA VPDVLTQARS LSAYPGLDLS
660 670 680 690 700
APGSGWRFGL YTPPGIVAES SRTYDALEDT LLLPRIVTRI EAVLSQAIAD
710 720 730 740 750
RDPKAAYDAL RVYLMLYDRA RFDAAQVEAW VLDDWARTDS AAVFGGRASM
760 770 780 790 800
IAHVEQLFRG ERIVQSPLIR NDALIRQARA FLDGSNATER LYERAKAAMN
810 820 830 840 850
KEAPDEFTLL RAVGPQAGTV FTRASGAPLA RGVPGLFTFD GYRRVFDKRL
860 870 880 890 900
AEFVRTARED DAWVMGRAYL GDAQKKTAEI ANALAGADDP LTDAIRRQYL
910 920 930 940 950
IEYAQQWDAF LGDIRTIGGT SLAFDLVVLR SFAAPDSPLE RLARAAVHET
960 970 980 990 1000
TLAQPEASAD RSFLQKASAQ LSQQADKALG VRAQERVERE LVDNRFAGLR
1010 1020 1030 1040 1050
EMVTGRADTQ TDARPGAPAG KSGLDAVANL LNDYYTALTV SDDALANNSM
1060 1070 1080 1090 1100
PPANDTAAKL KMAAQTMPAP FRSVLTGLAA QGSREVNRGI GQLLSRQLQA
1110 1120 1130 1140 1150
TVGDVCRLAI EGNYPFAPDS KRDVGIEDFT RVFAQGGVID DFFAKTLAPF
1160 1170 1180 1190 1200
VDTSTRPWRY KTLPGATEPV EGPDLEPFQH AKAIREVFFG APGQKQMAWK
1210 1220 1230 1240 1250
ADIRIPELDP TITSLAIDVD GQTALYQHGP VAPFAVSWPG PRGGVHAEIT
1260 1270 1280 1290 1300
ASPRIRPDTS AVSTDGPWAL LRLLQKGRVS GTATPGRTRV TLDFDGRKAV
1310 1320 1330 1340 1350
LDLASTGSVA NPLTSDVLKT FRCPGSMPMF SLADTGAPPG LPPGSPAAPT

SRVARDGR
Length:1,358
Mass (Da):146,278
Last modified:November 8, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i508BF79E910ADBEA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
CP000125 Genomic DNA Translation: ABA51989.1

NCBI Reference Sequences

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RefSeqi
WP_004529717.1, NC_007435.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ABA51989; ABA51989; BURPS1710b_A1689

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bpm:BURPS1710b_A1689

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000125 Genomic DNA Translation: ABA51989.1
RefSeqiWP_004529717.1, NC_007435.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiABA51989; ABA51989; BURPS1710b_A1689
KEGGibpm:BURPS1710b_A1689

Phylogenomic databases

HOGENOMiCLU_003353_2_0_4
KOiK11891
OMAiFFGYGGT
OrthoDBi393769at2

Enzyme and pathway databases

BioCyciBPSE320372:G1G58-6368-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR009612 IcmF-related
IPR025743 IcmF-related_N_dom
IPR010623 IcmF_C
IPR017731 T6SS_IcmF
PfamiView protein in Pfam
PF06761 IcmF-related, 1 hit
PF06744 IcmF_C, 1 hit
PF14331 ImcF-related_N, 1 hit
TIGRFAMsiTIGR03348 VI_IcmF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ3JHV7_BURP1
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3JHV7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: February 26, 2020
This is version 66 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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