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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:RHOS4_04260
ORF Names:RSP_1845
OrganismiRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Taxonomic identifieri272943 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
Proteomesi
  • UP000002703 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003038141 – 519Exodeoxyribonuclease 7 large subunitAdd BLAST519

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi272943.RSP_1845

Structurei

3D structure databases

SMRiQ3J5E0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVS Bacteria
COG1570 LUCA
HOGENOMiHOG000229266
KOiK03601
OMAiLVWPVKV
OrthoDBiPOG091H02EK
PhylomeDBiQ3J5E0

Family and domain databases

CDDicd04489 ExoVII_LU_OBF, 1 hit
HAMAPiMF_00378 Exonuc_7_L, 1 hit
InterProiView protein in InterPro
IPR003753 Exonuc_VII_L
IPR020579 Exonuc_VII_lsu_C
IPR025824 OB-fold_nuc-bd_dom
PANTHERiPTHR30008 PTHR30008, 1 hit
PfamiView protein in Pfam
PF02601 Exonuc_VII_L, 1 hit
PF13742 tRNA_anti_2, 1 hit
TIGRFAMsiTIGR00237 xseA, 1 hit

Sequencei

Sequence statusi: Complete.

Q3J5E0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDLFEDPAP SRNTPEFTVS ELSGAVKRVI EGEFGLVRVR GEIGRVSRPA
60 70 80 90 100
SGHLYFDLKD DRAVMAAICW KGQAGRLSVR PEEGMEVVAT GRMTTFPGQS
110 120 130 140 150
KYQIIVEDMA PAGAGALMAM LEKRRAALAA EGLFDAARKH PLPFLPRVIG
160 170 180 190 200
VVTSPSGAVI RDILHRLRDR FPSHVLIWPV AVQGEKCAPE VAAAIRGFNA
210 220 230 240 250
LPEGGPIPRP DLLIVARGGG SLEDLWGFNE EIVVRAAAES RIPLISAVGH
260 270 280 290 300
ETDTTLIDHA ADRRAPTPTA AAEMAVPVRL ELLAGLDGQV ARLSRCAAET
310 320 330 340 350
IRRRDQRLRD LARALPRLES LVAGPSQRFD LWSGRLSGAL GQSVAARRAR
360 370 380 390 400
LEPLGAHLRP RLLADLVARQ KDRLGDRTRS LETCLGRRAE RARDRFDALS
410 420 430 440 450
ARLAPAFARL IAETERATRR DAATLGTLAA RLDAAPEARL ARLSDRLEAL
460 470 480 490 500
DRLRQTLGYR ETLKRGYAVV RADGAVLTTK AEAGAAAMLE IEFQDGRLSV
510
GRGKTRKPKE EPPAQGSLL
Length:519
Mass (Da):56,330
Last modified:November 8, 2005 - v1
Checksum:i929317CE39872720
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000143 Genomic DNA Translation: ABA77994.1
RefSeqiWP_011337024.1, NZ_AKVW01000001.1
YP_351895.1, NC_007493.2

Genome annotation databases

EnsemblBacteriaiABA77994; ABA77994; RSP_1845
GeneIDi3719112
KEGGirsp:RSP_1845
PATRICifig|272943.9.peg.732

Similar proteinsi

Entry informationi

Entry nameiEX7L_RHOS4
AccessioniPrimary (citable) accession number: Q3J5E0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: November 8, 2005
Last modified: October 25, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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