Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chemotaxis response regulator protein-glutamate methylesterase

Gene

cheB

Organism
Pseudoalteromonas haloplanktis (strain TAC 125)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR.UniRule annotation

Catalytic activityi

Protein L-glutamate O5-methyl ester + H2O = protein L-glutamate + methanol.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei209UniRule annotation1
Active sitei236UniRule annotation1
Active sitei333UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processChemotaxis

Enzyme and pathway databases

BioCyciPHAL326442:PSHA_RS03965-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis response regulator protein-glutamate methylesteraseUniRule annotation (EC:3.1.1.61UniRule annotation)
Gene namesi
Name:cheBUniRule annotation
Ordered Locus Names:PSHAa0813
OrganismiPseudoalteromonas haloplanktis (strain TAC 125)
Taxonomic identifieri326442 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
Proteomesi
  • UP000006843 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002254681 – 391Chemotaxis response regulator protein-glutamate methylesteraseAdd BLAST391

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei554-aspartylphosphateUniRule annotation1

Post-translational modificationi

Phosphorylated by CheA. Phosphorylation suppresses the inhibitory activity of the N-terminal domain.UniRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi326442.PSHAa0813

Structurei

3D structure databases

ProteinModelPortaliQ3IDZ3
SMRiQ3IDZ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 121Response regulatoryPROSITE-ProRule annotationAdd BLAST118
Domaini197 – 391CheB-type methylesteraseUniRule annotationAdd BLAST195

Domaini

The N-terminal regulatory domain inhibits the activity of the C-terminal effector domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMP Bacteria
COG2201 LUCA
HOGENOMiHOG000151424
KOiK03412
OMAiYGMPMAV
OrthoDBiPOG091H045J

Family and domain databases

CDDicd16432 CheB_Rec, 1 hit
cd00156 REC, 1 hit
Gene3Di3.40.50.180, 1 hit
HAMAPiMF_00099 CheB_methylest, 1 hit
InterProiView protein in InterPro
IPR035909 CheB_C
IPR011006 CheY-like_superfamily
IPR008248 Sig_transdc_resp-reg_CheB
IPR000673 Sig_transdc_resp-reg_Me-estase
IPR001789 Sig_transdc_resp-reg_receiver
PfamiView protein in Pfam
PF01339 CheB_methylest, 1 hit
PF00072 Response_reg, 1 hit
PIRSFiPIRSF000876 RR_chemtxs_CheB, 1 hit
SMARTiView protein in SMART
SM00448 REC, 1 hit
SUPFAMiSSF52172 SSF52172, 1 hit
SSF52738 SSF52738, 1 hit
PROSITEiView protein in PROSITE
PS50122 CHEB, 1 hit
PS50110 RESPONSE_REGULATORY, 1 hit

Sequencei

Sequence statusi: Complete.

Q3IDZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVKVLVVDD SSFFRRRVSE ILELDSEIEV IGFAVNGRDA VEKAASLRPD
60 70 80 90 100
MITMDVEMPV LDGISAVKEI MASNPTPILM FSSLTRSGAT ATLDALDAGA
110 120 130 140 150
MDFLPKKFED IARNNEDAIK LLQSKVKEIG RQRIRRVASP RPSSINKPLF
160 170 180 190 200
TPTSAPSALA ARFAQTNKTA TTVVQPERSF NNSPVTSRSA IVTKRASGKH
210 220 230 240 250
YQLVAIGTST GGPVALQTIL TQLPANFPHP ILLIQHMPAA FTPAFAARLN
260 270 280 290 300
SLCKIQVKEA QQGDRLQAGV AYLAPGGQQM MIDGRGASRT LRVFEDNSER
310 320 330 340 350
ISYKPSVDVT FASAAKAYQG DVLAIVLTGM GADGREGARM LKQSGATIWA
360 370 380 390
QDEKSCVVYG MPQAIANAGL ASESLPLDEV AIRLKTEVGC G
Length:391
Mass (Da):41,874
Last modified:November 8, 2005 - v1
Checksum:i3439796640765D1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR954246 Genomic DNA Translation: CAI85894.1
RefSeqiWP_011327506.1, NC_007481.1

Genome annotation databases

EnsemblBacteriaiCAI85894; CAI85894; PSHAa0813
KEGGipha:PSHAa0813
PATRICifig|326442.8.peg.775

Similar proteinsi

Entry informationi

Entry nameiCHEB_PSEHT
AccessioniPrimary (citable) accession number: Q3IDZ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: November 8, 2005
Last modified: June 20, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health