Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 104 (02 Dec 2020)
Sequence version 1 (08 Nov 2005)
Previous versions | rss
Add a publicationFeedback
Protein

Alpha-synuclein

Gene

SNCA

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi2CopperBy similarity1
Metal bindingi50CopperBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCopper, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Alpha-synuclein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SNCA
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000314985 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8
  • UP000008227 Componenti: Chromosome 8

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:93285, SNCA

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell junction, Cytoplasm, Membrane, Nucleus, Secreted, Synapse

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001840291 – 140Alpha-synucleinAdd BLAST140

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
Modified residuei87PhosphoserineBy similarity1
Modified residuei125Phosphotyrosine; by FYNBy similarity1
Modified residuei129Phosphoserine; by PLK2By similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated, predominantly on serine residues.By similarity
Ubiquitinated. The predominant conjugate is the diubiquitinated form (By similarity).By similarity

Keywords - PTMi

Acetylation, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3I5G7

PeptideAtlas

More...
PeptideAtlasi
Q3I5G7

PRoteomics IDEntifications database

More...
PRIDEi
Q3I5G7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSSSCG00000009203, Expressed in Ammon's horn and 30 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q3I5G7, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Soluble monomer. Homotetramer. A dynamic intracellular population of tetramers and monomers coexists normally and the tetramer plays an essential role in maintaining homeostasis (By similarity).

Interacts with UCHL1 (By similarity).

Interacts with phospholipase D and histones.

Interacts (via N-terminus) with synphilin-1/SNCAIP; this interaction promotes formation of SNCA inclusions in the cytoplasm.

Interacts with CALM1.

Interacts with STXBP1; this interaction controls SNCA self-replicating aggregation.

Interacts with SNARE components VAMP2 and SNAP25; these interactions allows SNARE complex assembly and integrity (By similarity).

Interacts with RPH3A and RAB3A (By similarity).

Interacts with SERF1A; this interaction promotes the aggregation of SNCA (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q3I5G7, 1 interactor

Molecular INTeraction database

More...
MINTi
Q3I5G7

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000009812

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q3I5G7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni111 – 140Interaction with SERF1ABy similarityAdd BLAST30

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the synuclein family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S0Q7, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183175

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_129378_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3I5G7

Identification of Orthologs from Complete Genome Data

More...
OMAi
PENEAYE

Database of Orthologous Groups

More...
OrthoDBi
1544450at2759

TreeFam database of animal gene trees

More...
TreeFami
TF332776

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001058, Synuclein
IPR002460, Synuclein_alpha

The PANTHER Classification System

More...
PANTHERi
PTHR13820, PTHR13820, 1 hit
PTHR13820:SF5, PTHR13820:SF5, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01387, Synuclein, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01212, ASYNUCLEIN
PR01211, SYNUCLEIN

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q3I5G7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH
60 70 80 90 100
GVTTVAEKTK EQVTNVGEAV VTGVTAVAQK TVEGAGSIAA ATGFGKKDQL
110 120 130 140
GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
Length:140
Mass (Da):14,520
Last modified:November 8, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i175E2A66B448536C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A5S6H0Q1A0A5S6H0Q1_PIG
Alpha-synuclein
SNCA
142Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5S6HHB4A0A5S6HHB4_PIG
Alpha-synuclein
SNCA
126Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5S6HL47A0A5S6HL47_PIG
Alpha-synuclein
SNCA
130Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5G2R2I6A0A5G2R2I6_PIG
Alpha-synuclein
SNCA
113Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5S6I759A0A5S6I759_PIG
Alpha-synuclein
SNCA
112Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ073395 mRNA Translation: AAZ23150.1

NCBI Reference Sequences

More...
RefSeqi
NP_001032222.1, NM_001037145.1
XP_005667046.1, XM_005666989.2
XP_005667047.1, XM_005666990.1
XP_005667048.1, XM_005666991.2
XP_013834472.1, XM_013979018.1
XP_013834473.1, XM_013979019.1
XP_013834474.1, XM_013979020.1
XP_013834475.1, XM_013979021.1
XP_013834476.1, XM_013979022.1
XP_013834477.1, XM_013979023.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000010077; ENSSSCP00000009812; ENSSSCG00000009203
ENSSSCT00005014538; ENSSSCP00005008658; ENSSSCG00005009534
ENSSSCT00005014573; ENSSSCP00005008690; ENSSSCG00005009534
ENSSSCT00005014602; ENSSSCP00005008712; ENSSSCG00005009534
ENSSSCT00005014605; ENSSSCP00005008714; ENSSSCG00005009534
ENSSSCT00015009339; ENSSSCP00015003727; ENSSSCG00015006869
ENSSSCT00025097849; ENSSSCP00025042999; ENSSSCG00025071166
ENSSSCT00030057605; ENSSSCP00030026173; ENSSSCG00030041450
ENSSSCT00045041478; ENSSSCP00045028787; ENSSSCG00045024277
ENSSSCT00050001298; ENSSSCP00050000342; ENSSSCG00050001043
ENSSSCT00055060116; ENSSSCP00055048172; ENSSSCG00055030213
ENSSSCT00060075237; ENSSSCP00060032494; ENSSSCG00060055210
ENSSSCT00070030805; ENSSSCP00070025698; ENSSSCG00070015592
ENSSSCT00070030816; ENSSSCP00070025706; ENSSSCG00070015592
ENSSSCT00070030829; ENSSSCP00070025714; ENSSSCG00070015592
ENSSSCT00070030833; ENSSSCP00070025718; ENSSSCG00070015592
ENSSSCT00070030837; ENSSSCP00070025722; ENSSSCG00070015592

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
641350

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ssc:641350

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ073395 mRNA Translation: AAZ23150.1
RefSeqiNP_001032222.1, NM_001037145.1
XP_005667046.1, XM_005666989.2
XP_005667047.1, XM_005666990.1
XP_005667048.1, XM_005666991.2
XP_013834472.1, XM_013979018.1
XP_013834473.1, XM_013979019.1
XP_013834474.1, XM_013979020.1
XP_013834475.1, XM_013979021.1
XP_013834476.1, XM_013979022.1
XP_013834477.1, XM_013979023.1

3D structure databases

SMRiQ3I5G7
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ3I5G7, 1 interactor
MINTiQ3I5G7
STRINGi9823.ENSSSCP00000009812

Proteomic databases

PaxDbiQ3I5G7
PeptideAtlasiQ3I5G7
PRIDEiQ3I5G7

Genome annotation databases

EnsembliENSSSCT00000010077; ENSSSCP00000009812; ENSSSCG00000009203
ENSSSCT00005014538; ENSSSCP00005008658; ENSSSCG00005009534
ENSSSCT00005014573; ENSSSCP00005008690; ENSSSCG00005009534
ENSSSCT00005014602; ENSSSCP00005008712; ENSSSCG00005009534
ENSSSCT00005014605; ENSSSCP00005008714; ENSSSCG00005009534
ENSSSCT00015009339; ENSSSCP00015003727; ENSSSCG00015006869
ENSSSCT00025097849; ENSSSCP00025042999; ENSSSCG00025071166
ENSSSCT00030057605; ENSSSCP00030026173; ENSSSCG00030041450
ENSSSCT00045041478; ENSSSCP00045028787; ENSSSCG00045024277
ENSSSCT00050001298; ENSSSCP00050000342; ENSSSCG00050001043
ENSSSCT00055060116; ENSSSCP00055048172; ENSSSCG00055030213
ENSSSCT00060075237; ENSSSCP00060032494; ENSSSCG00060055210
ENSSSCT00070030805; ENSSSCP00070025698; ENSSSCG00070015592
ENSSSCT00070030816; ENSSSCP00070025706; ENSSSCG00070015592
ENSSSCT00070030829; ENSSSCP00070025714; ENSSSCG00070015592
ENSSSCT00070030833; ENSSSCP00070025718; ENSSSCG00070015592
ENSSSCT00070030837; ENSSSCP00070025722; ENSSSCG00070015592
GeneIDi641350
KEGGissc:641350

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6622
VGNCiVGNC:93285, SNCA

Phylogenomic databases

eggNOGiENOG502S0Q7, Eukaryota
GeneTreeiENSGT00950000183175
HOGENOMiCLU_129378_1_0_1
InParanoidiQ3I5G7
OMAiPENEAYE
OrthoDBi1544450at2759
TreeFamiTF332776

Gene expression databases

BgeeiENSSSCG00000009203, Expressed in Ammon's horn and 30 other tissues
ExpressionAtlasiQ3I5G7, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001058, Synuclein
IPR002460, Synuclein_alpha
PANTHERiPTHR13820, PTHR13820, 1 hit
PTHR13820:SF5, PTHR13820:SF5, 1 hit
PfamiView protein in Pfam
PF01387, Synuclein, 1 hit
PRINTSiPR01212, ASYNUCLEIN
PR01211, SYNUCLEIN

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSYUA_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3I5G7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: November 8, 2005
Last modified: December 2, 2020
This is version 104 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again