Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 133 (02 Jun 2021)
Sequence version 1 (22 Nov 2005)
Previous versions | rss
Add a publicationFeedback
Protein

Glucose-fructose oxidoreductase domain-containing protein 2

Gene

GFOD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Promotes matrix assembly.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q3B7J2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glucose-fructose oxidoreductase domain-containing protein 2 (EC:1.-.-.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GFOD2
ORF Names:UNQ9430/PRO34691
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28159, GFOD2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q3B7J2

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000141098.12

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
81577

Open Targets

More...
OpenTargetsi
ENSG00000141098

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA144596430

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q3B7J2, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GFOD2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
121942382

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000028297226 – 385Glucose-fructose oxidoreductase domain-containing protein 2Add BLAST360

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q3B7J2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q3B7J2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q3B7J2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3B7J2

PeptideAtlas

More...
PeptideAtlasi
Q3B7J2

PRoteomics IDEntifications database

More...
PRIDEi
Q3B7J2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
61654 [Q3B7J2-1]
61655 [Q3B7J2-2]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q3B7J2-1 [Q3B7J2-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q3B7J2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3B7J2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000141098, Expressed in cerebellum and 200 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q3B7J2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q3B7J2, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000141098, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
123537, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q3B7J2, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000268797

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q3B7J2, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q3B7J2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Gfo/Idh/MocA family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2742, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156501

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_023194_8_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3B7J2

Identification of Orthologs from Complete Genome Data

More...
OMAi
VMICDVR

Database of Orthologous Groups

More...
OrthoDBi
673027at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q3B7J2

TreeFam database of animal gene trees

More...
TreeFami
TF323246

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004104, Gfo/Idh/MocA-like_OxRdtase_C
IPR000683, Gfo/Idh/MocA-like_OxRdtase_N
IPR036291, NAD(P)-bd_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01408, GFO_IDH_MocA, 1 hit
PF02894, GFO_IDH_MocA_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51735, SSF51735, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q3B7J2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKMLPGVGVF GTGSSARVLV PLLRAEGFTV EALWGKTEEE AKQLAEEMNI
60 70 80 90 100
AFYTSRTDDI LLHQDVDLVC ISIPPPLTRQ ISVKALGIGK NVVCEKAATS
110 120 130 140 150
VDAFRMVTAS RYYPQLMSLV GNVLRFLPAF VRMKQLISEH YVGAVMICDA
160 170 180 190 200
RIYSGSLLSP SYGWICDELM GGGGLHTMGT YIVDLLTHLT GRRAEKVHGL
210 220 230 240 250
LKTFVRQNAA IRGIRHVTSD DFCFFQMLMG GGVCSTVTLN FNMPGAFVHE
260 270 280 290 300
VMVVGSAGRL VARGADLYGQ KNSATQEELL LRDSLAVGAG LPEQGPQDVP
310 320 330 340 350
LLYLKGMVYM VQALRQSFQG QGDRRTWDRT PVSMAASFED GLYMQSVVDA
360 370 380
IKRSSRSGEW EAVEVLTEEP DTNQNLCEAL QRNNL
Length:385
Mass (Da):42,255
Last modified:November 22, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD516EE4CC5CF5667
GO
Isoform 2 (identifier: Q3B7J2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-105: Missing.

Show »
Length:280
Mass (Da):30,912
Checksum:iBDB78411672FE58F
GO
Isoform 3 (identifier: Q3B7J2-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     87-112: GIGKNVVCEKAATSVDAFRMVTASRY → GTPGRPQQGQIMSLPLGSPLRVTPLL
     113-385: Missing.

Show »
Length:112
Mass (Da):12,110
Checksum:iC6E746EFD015716A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WT49A0A087WT49_HUMAN
Glucose-fructose oxidoreductase dom...
GFOD2
90Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WTD9A0A087WTD9_HUMAN
Glucose-fructose oxidoreductase dom...
GFOD2
88Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X156A0A087X156_HUMAN
Glucose-fructose oxidoreductase dom...
GFOD2
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAQ88536 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti8G → D in BAB85066 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_054433231G → V. Corresponds to variant dbSNP:rs11539687Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0242621 – 105Missing in isoform 2. 1 PublicationAdd BLAST105
Alternative sequenceiVSP_05518587 – 112GIGKN…TASRY → GTPGRPQQGQIMSLPLGSPL RVTPLL in isoform 3. 1 PublicationAdd BLAST26
Alternative sequenceiVSP_055186113 – 385Missing in isoform 3. 1 PublicationAdd BLAST273

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY358169 mRNA Translation: AAQ88536.1 Different initiation.
AK074382 mRNA Translation: BAB85066.1
AK307280 mRNA No translation available.
AC010530 Genomic DNA No translation available.
BC000757 mRNA Translation: AAH00757.1
BC002943 mRNA Translation: AAH02943.2
BC107585 mRNA Translation: AAI07586.1
AL832904 mRNA Translation: CAH10637.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10845.1 [Q3B7J2-1]
CCDS59268.1 [Q3B7J2-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001230579.1, NM_001243650.1 [Q3B7J2-3]
NP_110446.3, NM_030819.3 [Q3B7J2-1]
XP_006721351.1, XM_006721288.3 [Q3B7J2-2]
XP_016879227.1, XM_017023738.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000268797; ENSP00000268797; ENSG00000141098 [Q3B7J2-1]
ENST00000602279; ENSP00000478260; ENSG00000141098 [Q3B7J2-3]
ENST00000602496; ENSP00000473641; ENSG00000141098 [Q3B7J2-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
81577

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:81577

UCSC genome browser

More...
UCSCi
uc002eub.4, human [Q3B7J2-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358169 mRNA Translation: AAQ88536.1 Different initiation.
AK074382 mRNA Translation: BAB85066.1
AK307280 mRNA No translation available.
AC010530 Genomic DNA No translation available.
BC000757 mRNA Translation: AAH00757.1
BC002943 mRNA Translation: AAH02943.2
BC107585 mRNA Translation: AAI07586.1
AL832904 mRNA Translation: CAH10637.1
CCDSiCCDS10845.1 [Q3B7J2-1]
CCDS59268.1 [Q3B7J2-3]
RefSeqiNP_001230579.1, NM_001243650.1 [Q3B7J2-3]
NP_110446.3, NM_030819.3 [Q3B7J2-1]
XP_006721351.1, XM_006721288.3 [Q3B7J2-2]
XP_016879227.1, XM_017023738.1

3D structure databases

SMRiQ3B7J2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi123537, 4 interactors
IntActiQ3B7J2, 4 interactors
STRINGi9606.ENSP00000268797

PTM databases

iPTMnetiQ3B7J2
PhosphoSitePlusiQ3B7J2

Genetic variation databases

BioMutaiGFOD2
DMDMi121942382

Proteomic databases

EPDiQ3B7J2
MassIVEiQ3B7J2
MaxQBiQ3B7J2
PaxDbiQ3B7J2
PeptideAtlasiQ3B7J2
PRIDEiQ3B7J2
ProteomicsDBi61654 [Q3B7J2-1]
61655 [Q3B7J2-2]
TopDownProteomicsiQ3B7J2-1 [Q3B7J2-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
29615, 172 antibodies

The DNASU plasmid repository

More...
DNASUi
81577

Genome annotation databases

EnsembliENST00000268797; ENSP00000268797; ENSG00000141098 [Q3B7J2-1]
ENST00000602279; ENSP00000478260; ENSG00000141098 [Q3B7J2-3]
ENST00000602496; ENSP00000473641; ENSG00000141098 [Q3B7J2-3]
GeneIDi81577
KEGGihsa:81577
UCSCiuc002eub.4, human [Q3B7J2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
81577
DisGeNETi81577

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GFOD2
HGNCiHGNC:28159, GFOD2
HPAiENSG00000141098, Low tissue specificity
neXtProtiNX_Q3B7J2
OpenTargetsiENSG00000141098
PharmGKBiPA144596430
VEuPathDBiHostDB:ENSG00000141098.12

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2742, Eukaryota
GeneTreeiENSGT00940000156501
HOGENOMiCLU_023194_8_0_1
InParanoidiQ3B7J2
OMAiVMICDVR
OrthoDBi673027at2759
PhylomeDBiQ3B7J2
TreeFamiTF323246

Enzyme and pathway databases

PathwayCommonsiQ3B7J2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
81577, 3 hits in 990 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
GFOD2, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
81577
PharosiQ3B7J2, Tdark

Protein Ontology

More...
PROi
PR:Q3B7J2
RNActiQ3B7J2, protein

Gene expression databases

BgeeiENSG00000141098, Expressed in cerebellum and 200 other tissues
ExpressionAtlasiQ3B7J2, baseline and differential
GenevisibleiQ3B7J2, HS

Family and domain databases

InterProiView protein in InterPro
IPR004104, Gfo/Idh/MocA-like_OxRdtase_C
IPR000683, Gfo/Idh/MocA-like_OxRdtase_N
IPR036291, NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF01408, GFO_IDH_MocA, 1 hit
PF02894, GFO_IDH_MocA_C, 1 hit
SUPFAMiSSF51735, SSF51735, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGFOD2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3B7J2
Secondary accession number(s): Q69YL9
, Q6UXX6, Q7L648, Q8TE86, Q9BQ07, R4GNG5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: November 22, 2005
Last modified: June 2, 2021
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again