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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Chlorobium luteolum (strain DSM 273 / 2530) (Pelodictyon luteolum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei352Proton donorUniRule annotation1
Active sitei383UniRule annotation1
Active sitei511UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCLUT319225:G1G4U-1250-MONOMER
UniPathwayi
UPA00109;UER00181

UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Plut_1161
OrganismiChlorobium luteolum (strain DSM 273 / 2530) (Pelodictyon luteolum)
Taxonomic identifieri319225 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupPelodictyon
Proteomesi
  • UP000002709 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002309241 – 551Glucose-6-phosphate isomeraseAdd BLAST551

Interactioni

Protein-protein interaction databases

STRINGi319225.Plut_1161

Structurei

3D structure databases

ProteinModelPortaliQ3B3Q8
SMRiQ3B3Q8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q3B3Q8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLSRSAAWS ALVSHRQEVE QLHMRDMFMS DHDRFKHFSI RWNGLLLDYS
60 70 80 90 100
KNRINSRTMG LLVELARQAN LIEARDGMFA GEKINFTENR AVLHTALRRQ
110 120 130 140 150
PGYTLNVDGL DVPAEVDSVL RQMKAFTDKV VGGEWKGYTG KRITDVVNIG
160 170 180 190 200
IGGSDLGPCM VTEALRPFAD GAIAVHFVSN IDGTHVSEVL KRVDAETTLF
210 220 230 240 250
VIASKTFTTQ ETLTNSMTAR EWFLSRAIDP AHIALHFAAV STNRTKVVEF
260 270 280 290 300
GIDPENMFRF WDWVGGRYSL WSAIGLSIAL YLGFEAFQEL LRGARAMDEH
310 320 330 340 350
FQEAPLEENI PVILALLGVW YNNFFDVPSH AVIPYDQYLH RLPAYLQQLD
360 370 380 390 400
MESNGKRVDR LGNTVEYPTG PIIWGEPGTN SQHAFFQLLH QGTGFIPADF
410 420 430 440 450
ILPLKTQNPI GEHHDILVAN CFAQTEALMR GKSASEASEE LAAAGVDEET
460 470 480 490 500
MQMLVAHKVF PGNRPTNTLL LDEINPFTLG SLIAMYEHKV FVQGVIWQVN
510 520 530 540 550
SFDQWGVELG KQLAKAILPE LQSQKESDAH DASTNALINS YRSYREGQKV

G
Length:551
Mass (Da):61,755
Last modified:April 4, 2006 - v2
Checksum:i4D9737D4860AED39
GO

Sequence cautioni

The sequence ABB24023 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000096 Genomic DNA Translation: ABB24023.1 Different initiation.
RefSeqiWP_041464108.1, NC_007512.1

Genome annotation databases

EnsemblBacteriaiABB24023; ABB24023; Plut_1161
KEGGiplt:Plut_1161

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000096 Genomic DNA Translation: ABB24023.1 Different initiation.
RefSeqiWP_041464108.1, NC_007512.1

3D structure databases

ProteinModelPortaliQ3B3Q8
SMRiQ3B3Q8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi319225.Plut_1161

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB24023; ABB24023; Plut_1161
KEGGiplt:Plut_1161

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00181

UPA00138

BioCyciCLUT319225:G1G4U-1250-MONOMER

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiG6PI_CHLL7
AccessioniPrimary (citable) accession number: Q3B3Q8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: October 10, 2018
This is version 80 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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Main funding by: National Institutes of Health

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