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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Synechococcus sp. (strain CC9902)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciSSP316279:G1G4V-1639-MONOMER
UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:Syncc9902_1584
OrganismiSynechococcus sp. (strain CC9902)
Taxonomic identifieri316279 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000002712 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000238171 – 502Probable malate:quinone oxidoreductaseAdd BLAST502

Interactioni

Protein-protein interaction databases

STRINGi316279.Syncc9902_1584

Structurei

3D structure databases

ProteinModelPortaliQ3AWX1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiEPIAATK
OrthoDBiPOG091H0B7C

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 2 hits
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

Q3AWX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNDGTFDPE ASYDAVLVGA GIMSATLAAL LHELDPQLRL LLVERLEAPA
60 70 80 90 100
LESSAAVNNA GTGHAANCEL NYTPMQPNGR VATDKAVAIN AAFERSLEFW
110 120 130 140 150
GSLLERGRLT STDFLHRAAH ISAVWSPANI AFLRQRFEQL KDIPAFAEMR
160 170 180 190 200
WTEDRQDLAE WMPLVMEGRD PNQAVAATRI ERGTDVDFGA LTRAYLLPLQ
210 220 230 240 250
SSGALTVQYG TEVSNLKRLR RPNMTEGDWR VITKGPSGRR EVRAPFVFLG
260 270 280 290 300
AGGGALPLLQ RSGIPEGDDF AGFPVSGLWL VCNDADLAEQ QRAKVYGKAA
310 320 330 340 350
VGAPPMSVPH LDTRWMDGRR SLLFGPFAGF SSKFLKQGSL LDLPASVRPT
360 370 380 390 400
NLLPMLQVGA TNIELVRYLI NQLRQTPDQR FDALRDFLPT ARQDDWSLSV
410 420 430 440 450
AGQRVQIIKR SKEGGRLQLG TEVVAASDGS LAALLGASPG ASTAVTIMLE
460 470 480 490 500
VLQRCFPERL ASADWQARLK ALLPSFYSDP KSDPDVLKGM RERSDGLLGL

SR
Length:502
Mass (Da):54,805
Last modified:November 22, 2005 - v1
Checksum:i5ECDCA7884944FA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000097 Genomic DNA Translation: ABB26542.1
RefSeqiWP_011360359.1, NC_007513.1

Genome annotation databases

EnsemblBacteriaiABB26542; ABB26542; Syncc9902_1584
KEGGisye:Syncc9902_1584

Similar proteinsi

Entry informationi

Entry nameiMQO_SYNS9
AccessioniPrimary (citable) accession number: Q3AWX1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 22, 2005
Last modified: February 28, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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