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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Pelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei76NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciPCAR338963:G1G5C-805-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:Pcar_0760
OrganismiPelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1)
Taxonomic identifieri338963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesDesulfuromonadaceaePelobacter
Proteomesi
  • UP000002534 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002301431 – 398tRNA pseudouridine synthase DAdd BLAST398

Proteomic databases

PRIDEiQ3A6I8

Interactioni

Protein-protein interaction databases

STRINGi338963.Pcar_0760

Structurei

3D structure databases

ProteinModelPortaliQ3A6I8
SMRiQ3A6I8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini151 – 360TRUDUniRule annotationAdd BLAST210

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 1 hit
PfamiView protein in Pfam
PF01142 TruD, 1 hit
PIRSFiPIRSF037016 Pseudouridin_synth_euk_prd, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

Q3A6I8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANYLTAKLP GIGGSIKTCP DDFLVEELPL YPTCGEGEHL YLEVEKRGMT
60 70 80 90 100
TFELLKRLSR ALQVNERAMG YAGLKDAQAT TRQFISVTDC SAEQALALQL
110 120 130 140 150
QDIRILSARR HRNKLRLGHL AGNRFTITIR DIDSDALEKA RDILHVLQMT
160 170 180 190 200
GVPNFFGEQR YGALGNSHLI GQAIVQKNFS QAAAHIIGDP DKIIHPEWRQ
210 220 230 240 250
GAILYAENRL EEAEQALPRR MRNERNLVRS LRQGRSAEKA VRRLPGKLLR
260 270 280 290 300
LYLSAYQSHL FDRLVSMRLE SLETLWTGDI AYKHDNGACF LVTDAALEQP
310 320 330 340 350
RADRFEISPT APLFGHKVMM AEAQAGILEQ ALLAKEGITP DDFRLGAGLS
360 370 380 390
MPGERRPLRI PISETASNQQ GNELELSFSL PKGSFATTVL HEVMKTDV
Length:398
Mass (Da):44,480
Last modified:November 22, 2005 - v1
Checksum:i3A886529EDB84307
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000142 Genomic DNA Translation: ABA88019.1
RefSeqiWP_011340463.1, NC_007498.2

Genome annotation databases

EnsemblBacteriaiABA88019; ABA88019; Pcar_0760
KEGGipca:Pcar_0760

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000142 Genomic DNA Translation: ABA88019.1
RefSeqiWP_011340463.1, NC_007498.2

3D structure databases

ProteinModelPortaliQ3A6I8
SMRiQ3A6I8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi338963.Pcar_0760

Proteomic databases

PRIDEiQ3A6I8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA88019; ABA88019; Pcar_0760
KEGGipca:Pcar_0760

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Enzyme and pathway databases

BioCyciPCAR338963:G1G5C-805-MONOMER

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 1 hit
PfamiView protein in Pfam
PF01142 TruD, 1 hit
PIRSFiPIRSF037016 Pseudouridin_synth_euk_prd, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_PELCD
AccessioniPrimary (citable) accession number: Q3A6I8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: November 22, 2005
Last modified: November 7, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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