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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Gmet_1434
OrganismiGeobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Taxonomic identifieri269799 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000007073 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420261 – 562Arginine--tRNA ligaseAdd BLAST562

Proteomic databases

PRIDEiQ39VQ6

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi269799.Gmet_1434

Structurei

3D structure databases

ProteinModelPortaliQ39VQ6
SMRiQ39VQ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi130 – 140"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q39VQ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKDRVRSLVA EGIERCFADG SLASNQMPAI VIEKPAHAEH GDFACTVAMS
60 70 80 90 100
MAKAERKAPR VIAETIVKHI ENGESGIIGG IDIAGPGFIN FRIKNEAWSR
110 120 130 140 150
TLAVVEAAGA SFGRSCAGEE RKVQVEFVSA NPTGPLHIGH GRGAAIGDTI
160 170 180 190 200
CRLLSASGFD VTREFYYNDA GAQIANLALS VQSRCLGIEP GDPRWPADGY
210 220 230 240 250
QGDYIKDVAR SYLNRETVDA GDQHVTAAGD PNDLDAIRRF AVAYLRREQD
260 270 280 290 300
QDLLAFDVHF DVYSLESSLY TEGRVEEVVR RLIENGHTFE QDGALWLRTT
310 320 330 340 350
DFGDDKDRVM RKSDGSYTYF VPDVAYHLAK WERGFTRVIN EQGADHHSTI
360 370 380 390 400
TRVRAGLQAL NAGIPQEWPE YVLHQMVTVM RGGEEVKISK RAGSYVTLRD
410 420 430 440 450
LIDEVGRDAT RFFFLMRKPD SQLVFDIDLA KQQSLENPVY YVQYAHARIS
460 470 480 490 500
SIFEAACDRG ISVPSFPDAH VDLLETPEEI ELIKLIGSFP EVIEGSALSF
510 520 530 540 550
EPHRITYYLQ ELAGAFHSFY NKNRVIGEGK ELSSARLFLL KGVAQVLKNG
560
LALLGVSAPE KM
Length:562
Mass (Da):62,252
Last modified:June 27, 2006 - v2
Checksum:i04F8CEB87823CC87
GO

Sequence cautioni

The sequence ABB31668 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000148 Genomic DNA Translation: ABB31668.1 Different initiation.

Genome annotation databases

EnsemblBacteriaiABB31668; ABB31668; Gmet_1434
KEGGigme:Gmet_1434

Similar proteinsi

Entry informationi

Entry nameiSYR_GEOMG
AccessioniPrimary (citable) accession number: Q39VQ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 27, 2006
Last modified: May 23, 2018
This is version 87 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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