Arginine decarboxylase

Functionⁱ

Catalytic activityⁱ

L-arginine = agmatine + CO₂.

Cofactorⁱ

Protein has several cofactor binding sites:

Pathwayⁱ: agmatine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes agmatine from L-arginine.
Proteins known to be involved in this subpathway in this organism are:

Arginine decarboxylase, Arginine decarboxylase (GLYMA_06G007500), Arginine decarboxylase (100793552)

This subpathway is part of the pathway agmatine biosynthesis, which is itself part of Amine and polyamine biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes agmatine from L-arginine, the pathway agmatine biosynthesis and in Amine and polyamine biosynthesis.

GO - Molecular functionⁱ

arginine decarboxylase activity Source: UniProtKB-EC

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

arginine catabolic process Source: InterPro
putrescine biosynthetic process Source: UniProtKB-KW
spermidine biosynthetic process Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Decarboxylase, Lyase
Biological process	Putrescine biosynthesis, Spermidine biosynthesis
Ligand	Magnesium, Pyridoxal phosphate

Enzyme and pathway databases

BRENDAⁱ	4.1.1.19 2483
SABIO-RKⁱ	Q39827
UniPathwayⁱ	UPA00186;UER00284

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Arginine decarboxylase (EC:4.1.1.19) Short name: ADC Short name: ARGDC
Organismⁱ	Glycine max (Soybean) (Glycine hispida)
Taxonomic identifierⁱ	3847 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Mesangiospermae › eudicotyledons › Gunneridae › Pentapetalae › rosids › fabids › Fabales › Fabaceae › Papilionoideae › 50 kb inversion clade › NPAAA clade › indigoferoid/millettioid clade › Phaseoleae › Glycine › Soja
Proteomesⁱ	UP000008827 Componentⁱ: Unplaced

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000149954	1 – 692	Arginine decarboxylaseAdd BLAST		692

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	153	N6-(pyridoxal phosphate)lysineBy similarity		1

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	3847.GLYMA06G00990.1

STRINGⁱ

3847.GLYMA06G00990.1

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q39827
SMRⁱ	Q39827
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	337 – 347	Substrate-bindingBy similarityAdd BLAST		11

Sequence similaritiesⁱ

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.Curated

Phylogenomic databases

eggNOGⁱ	ENOG410IKSU Eukaryota COG1166 LUCA
KEGG Orthology (KO) More...KOⁱ	K01583

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd06830 PLPDE_III_ADC, 1 hit
Gene3Dⁱ	2.40.37.10, 3 hits 3.20.20.10, 1 hit
InterProⁱ	View protein in InterPro IPR009006 Ala_racemase/Decarboxylase_C IPR002985 Arg_decrbxlase IPR022657 De-COase2_CS IPR022644 De-COase2_N IPR022653 De-COase2_pyr-phos_BS IPR000183 Orn/DAP/Arg_de-COase IPR029066 PLP-binding_barrel
PANTHERⁱ	PTHR43295 PTHR43295, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02784 Orn_Arg_deC_N, 1 hit
PIRSFⁱ	PIRSF001336 Arg_decrbxlase, 1 hit
PRINTSⁱ	PR01180 ARGDCRBXLASE PR01179 ODADCRBXLASE
SUPFAMⁱ	SSF50621 SSF50621, 1 hit SSF51419 SSF51419, 1 hit
TIGRFAMsⁱ	TIGR01273 speA, 1 hit
PROSITEⁱ	View protein in PROSITE PS00878 ODR_DC_2_1, 1 hit PS00879 ODR_DC_2_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q39827-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPVLACCVDA AAPPGYAFAG DISFPAPIAF TGVPPATADD TNNSNNHWSP 
        60         70         80         90        100
SLSAALYNVD GWGGPYFAVN TAGNISVRPH GSDTVSHQEI DLLKIVKKAS 
       110        120        130        140        150
DPKSLGGLSL QLPLIARFPD VLKNRLESLQ SAFDYAIQSG GYESHYQGVY 
       160        170        180        190        200
PVKCNQDRFV VEDIVKFGSP FRFGLEAGSK PELLLAMSCL CKGNPDGLLI 
       210        220        230        240        250
CNGFKDAEYI SLALVANKLA LNTVIVVEQE EEVDLIVELS KKLCIKPVIG 
       260        270        280        290        300
LRAKLRTKHS GHFGGIFRRR GKFGLTTARV LRVVKNLDLA GMLDCLQLLH 
       310        320        330        340        350
FHIGSQIPST ALLADGVGEA AQIYCELVRL GANMRVIDIG GGLGIDYDGS 
       360        370        380        390        400
KSCDSDISVE YGLEEYAAAV VHAVQCVCDR SVKHPVICSE SGRAIVSHHS 
       410        420        430        440        450
VLIFEAVGTS STNGGGAPPA LSAHYLAEEL SEDYGYLSEL AFRGDYETCL 
       460        470        480        490        500
VYTEEMKERC VEQFKQGTVC MEQLAAVEGL CELVRKAVGA AESVRRYHVN 
       510        520        530        540        550
LSIFTSVPDA WGIEQVFPII PIHRLDEKPS VRGILSDLTC DSDGKIDKFI 
       560        570        580        590        600
NGESSLPLHE MEGGRTYYLG MFLGGAYEEA LGGVHNLFGG PSVVRVSQSD 
       610        620        630        640        650
GPHSFAVTRA VPGPSCGDVL RVMQHQPELM FETLKHRAQE YVSHDNAAAL 
       660        670        680        690 
LAAGLARTFD RMPYLLSLSS FVADDVAAAV PAAQDLGEQW SY

Length:692

Mass (Da):74,595

Last modified:November 1, 1996 - v1

Checksum:ⁱ31BA9C207B5A6EF3

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U35367 mRNA Translation: AAD09204.1
PIRⁱ	T06593
NCBI Reference Sequences More...RefSeqⁱ	NP_001238359.1, NM_001251430.1
UniGeneⁱ	Gma.18066

Genome annotation databases

GeneIDⁱ	548071
KEGGⁱ	gmx:548071

Protein	Similar proteins		Species	Score	Length	Source
Q39827	Arginine decarboxylase		SOYBN		697	UniRef90_Q39827
UPI00098DB21E		CAJCA		678
Arginine decarboxylase		SOYBN		691

Protein	Similar proteins		Species	Score	Length	Source
Q39827	Arginine decarboxylase 2		ARATH		711	UniRef50_O23141
Arginine decarboxylase		BRAJU		702
Arginine decarboxylase		DIACA		725
Arginine decarboxylase 1		ORYSJ		702
Arginine decarboxylase		PEA		728
+319

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U35367 mRNA Translation: AAD09204.1
PIRⁱ	T06593
RefSeqⁱ	NP_001238359.1, NM_001251430.1
UniGeneⁱ	Gma.18066

3D structure databases

ProteinModelPortalⁱ	Q39827
SMRⁱ	Q39827
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	3847.GLYMA06G00990.1

STRINGⁱ

3847.GLYMA06G00990.1

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	548071
KEGGⁱ	gmx:548071

Phylogenomic databases

eggNOGⁱ	ENOG410IKSU Eukaryota COG1166 LUCA
KOⁱ	K01583

Enzyme and pathway databases

UniPathwayⁱ	UPA00186;UER00284
BRENDAⁱ	4.1.1.19 2483
SABIO-RKⁱ	Q39827

Family and domain databases

CDDⁱ	cd06830 PLPDE_III_ADC, 1 hit
Gene3Dⁱ	2.40.37.10, 3 hits 3.20.20.10, 1 hit
InterProⁱ	View protein in InterPro IPR009006 Ala_racemase/Decarboxylase_C IPR002985 Arg_decrbxlase IPR022657 De-COase2_CS IPR022644 De-COase2_N IPR022653 De-COase2_pyr-phos_BS IPR000183 Orn/DAP/Arg_de-COase IPR029066 PLP-binding_barrel
PANTHERⁱ	PTHR43295 PTHR43295, 1 hit
Pfamⁱ	View protein in Pfam PF02784 Orn_Arg_deC_N, 1 hit
PIRSFⁱ	PIRSF001336 Arg_decrbxlase, 1 hit
PRINTSⁱ	PR01180 ARGDCRBXLASE PR01179 ODADCRBXLASE
SUPFAMⁱ	SSF50621 SSF50621, 1 hit SSF51419 SSF51419, 1 hit
TIGRFAMsⁱ	TIGR01273 speA, 1 hit
PROSITEⁱ	View protein in PROSITE PS00878 ODR_DC_2_1, 1 hit PS00879 ODR_DC_2_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SPE1_SOYBN
Accessionⁱ	Q39827Primary (citable) accession number: Q39827
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
	Last sequence update:	November 1, 1996
	Last modified:	September 12, 2018
	This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Plant Protein Annotation Program

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UniProtKB - Q39827 (SPE1_SOYBN)

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: agmatine biosynthesis

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GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

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Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Keywords - Technical termi

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Functionⁱ

Pathwayⁱ: agmatine biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ