Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 85 (05 Jun 2019)
Sequence version 1 (01 Nov 1997)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Dynein gamma chain, flagellar outer arm

Gene

ODA2

Organism
Chlamydomonas reinhardtii (Chlamydomonas smithii)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Force generating protein of eukaryotic cilia and flagella. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi1819 – 1826ATPSequence analysis8
Nucleotide bindingi2099 – 2106ATPSequence analysis8
Nucleotide bindingi2425 – 2432ATPSequence analysis8
Nucleotide bindingi2802 – 2809ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor protein
Biological processCilium biogenesis/degradation
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dynein gamma chain, flagellar outer arm
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ODA2
Synonyms:ODA-2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiChlamydomonas reinhardtii (Chlamydomonas smithii)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3055 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeChlorophytaChlorophyceaeChlamydomonadalesChlamydomonadaceaeChlamydomonas

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Dynein, Flagellum, Microtubule

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001146501 – 4485Dynein gamma chain, flagellar outer armAdd BLAST4485

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q39575

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Consists of at least 3 heavy chains (alpha, beta and gamma), 2 intermediate chains and 8 light chains.

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q39575, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3055.EDO97301

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q39575

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 1780StemBy similarityAdd BLAST1780
Regioni1781 – 2002AAA 1By similarityAdd BLAST222
Regioni2061 – 2279AAA 2By similarityAdd BLAST219
Regioni2384 – 2638AAA 3By similarityAdd BLAST255
Regioni2763 – 3013AAA 4By similarityAdd BLAST251
Regioni3077 – 3343StalkBy similarityAdd BLAST267
Regioni3412 – 3643AAA 5By similarityAdd BLAST232
Regioni3857 – 4071AAA 6By similarityAdd BLAST215

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili449 – 469Sequence analysisAdd BLAST21
Coiled coili804 – 838Sequence analysisAdd BLAST35
Coiled coili1093 – 1114Sequence analysisAdd BLAST22
Coiled coili1275 – 1297Sequence analysisAdd BLAST23
Coiled coili1699 – 1727Sequence analysisAdd BLAST29
Coiled coili3077 – 3099Sequence analysisAdd BLAST23
Coiled coili3196 – 3227Sequence analysisAdd BLAST32
Coiled coili3265 – 3343Sequence analysisAdd BLAST79
Coiled coili3569 – 3663Sequence analysisAdd BLAST95

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Dynein heavy chains probably consist of an N-terminal stem (which binds cargo and interacts with other dynein components), and the head or motor domain. The motor contains six tandemly-linked AAA domains in the head, which form a ring. A stalk-like structure (formed by two of the coiled coil domains) protrudes between AAA 4 and AAA 5 and terminates in a microtubule-binding site. A seventh domain may also contribute to this ring; it is not clear whether the N-terminus or the C-terminus forms this extra domain. There are four well-conserved and two non-conserved ATPase sites, one per AAA domain. Probably only one of these (within AAA 1) actually hydrolyzes ATP, the others may serve a regulatory function.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the dynein heavy chain family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3595 Eukaryota
COG5245 LUCA

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.20.180.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR035699 AAA_6
IPR035706 AAA_9
IPR041658 AAA_lid_11
IPR042219 AAA_lid_11_sf
IPR026983 DHC_fam
IPR041589 DNAH3_AAA_lid_1
IPR042228 Dynein_2_C
IPR042222 Dynein_2_N
IPR041466 Dynein_AAA5_ext
IPR041228 Dynein_C
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_D6_P-loop
IPR013594 Dynein_heavy_dom-1
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR10676 PTHR10676, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF17857 AAA_lid_1, 1 hit
PF18198 AAA_lid_11, 1 hit
PF08385 DHC_N1, 1 hit
PF08393 DHC_N2, 1 hit
PF17852 Dynein_AAA_lid, 1 hit
PF18199 Dynein_C, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q39575-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALDNRHRLI VGKLAEAFGL PENVIEKTLT QDKQAVNSFF TPAGPPSLVF
60 70 80 90 100
VYQVKEDKLK DGSVGPVDNK PTLHRIGPHE RIHNSVYFTR LNPKGINEKT
110 120 130 140 150
LEADMGSGEL SVLWALENFK AIVSDLYLPI MQEQQQWGKM STEYLEDFLS
160 170 180 190 200
STAKFGSMLT EAVATVSGGV EPMPDPRYID QYGDLRPAGI TQAAGDDDTL
210 220 230 240 250
QEMEECLTEW CREAELLLNQ TNKIKDGEER GPDTELEYWR TRMSNFNSIT
260 270 280 290 300
EHLKTKECKL VLGICSHAKT KAYLRWRGLD VQITDAANES KDNVKYLATL
310 320 330 340 350
EKSMEPMYQG RVTDITESLP ALMTNVRMMY TIARFYSTAE HMTRLFTKIT
360 370 380 390 400
NQLVRRCKEQ IMENGKIWDQ DKVTLIGNMK VSVELANVYR QQYRLAKETL
410 420 430 440 450
AAQPKSKQFD FDEQAIFLKF DLSSKALHKL IDMFTTIHQF SSLEQHTHIE
460 470 480 490 500
GLDTMLKSLN NIIDDVKRKP YDLLDYSRNA FDTDFLEFNV QINDLELQLQ
510 520 530 540 550
GFVNASFEHI TSTEHALSLL AQFQAIMQRE TLQQDLENKY MVIFQNYAKD
560 570 580 590 600
LDAVQKLYEK NKYEPPVPRN APPVAGNIMW ARQLLRRIEA PMQLAQNKNL
610 620 630 640 650
LAAKESKKNI KTYNKVAKAL IEFETLWHQA WIKSIEQCKA GLAAPLLVQH
660 670 680 690 700
PDTGKILVNF DKEIMQLVRE AKYMQRFNIR CSSPSQMVLL QEEKFKFYHN
710 720 730 740 750
QLTHLVREYE HVLGRGATIK PLLRPHLDDM ERKIAPGFAV LTWTSLNIDG
760 770 780 790 800
YLHRFKQGLA RLEELVRKVV DLTENRVDSN LGAISSTLLV ELPTDRSFTY
810 820 830 840 850
EGFVEQNRFQ KKQAELLAIR NEEVRRAIED LYTLVRNYPR ENTEDVLDEK
860 870 880 890 900
EVSLLVRHYS KNMYNAIMQC TLNSLQAMKR RLGSKTTTGI FFMERPFFDV
910 920 930 940 950
DVELKVPSVC MNPTLEEIQA AINQCAKKVL TISKQLPAWG MDNVATYHEM
960 970 980 990 1000
MRGDRRWVKA VLRLTGSVEG IKTQVGEYIR TFDKYDFLWK EDLQAAYDHF
1010 1020 1030 1040 1050
MRSNPTLEAF EAELKKYMAI ETEVTMINGV NNIGALSLET HPLKNSLKAE
1060 1070 1080 1090 1100
AVSWKTQFAQ NLHKQCSDDL KLDNYIRDTN SKFHRKIEDL EDVRNVMAVL
1110 1120 1130 1140 1150
KEVREKESEI DNLIGPIEEM YGLLMRYEVR VPKEETTMVS DLRYGWKKLK
1160 1170 1180 1190 1200
KVATEVSDNL TRLQVGFKRE LIKEVKTFVV DAQMFRKDWE ANAMVPGLDP
1210 1220 1230 1240 1250
QEAVDRLRKF QQMFEVRKRK WENYSSGEEL FGLPVTQYPE LEQTEKEIQM
1260 1270 1280 1290 1300
LDRLYSLYVA VITTIKGYGD YFWVDVVEKI DEMGEQVQQY QNQSKKLPKL
1310 1320 1330 1340 1350
RDWPAYNACR KTIDDFLEML PLFQALTHKS MRERHWKEVM RVTGHELNLA
1360 1370 1380 1390 1400
EDHFKLQHLL DCNVLRYRED IEDLTGAAVK EEIIEVKLNQ LKADWATANL
1410 1420 1430 1440 1450
ALAEYKNRGP VILKPSDTSE LMEKLEESQM TLGSMATNRY SAPFRDEVQA
1460 1470 1480 1490 1500
WSIKLSTVSE IIEQWLMVQS MWQYMEAVFS GGDIVKQLPQ EAKRFLNIDK
1510 1520 1530 1540 1550
NFMKIVSNAL ETQNVINTCF GNELMKNMLP HLHEQLEMCQ KSLSAYLEQK
1560 1570 1580 1590 1600
RAEFPRFTCV GPHLLEICRW AHDPPSVVPH FQSGLFDSLS NVTFDRIDKT
1610 1620 1630 1640 1650
RMTEMFSQQN EKVEFERPVD AKGNIEVWLQ RLVDGMEDTV KQIIKRAVRN
1660 1670 1680 1690 1700
VAEMPLEDFV FGHPAQVSLL GIQFQWTAET QMALSSAKVD KTIMNKNMKK
1710 1720 1730 1740 1750
VDALLRDMVN ITVRLDLTKN QRTNLETCIT VHMHQKESTE DLVKKKIKDP
1760 1770 1780 1790 1800
TDFEWLKQVR FYWRDDKDTV IISICDVDFE YSFEYLGVKE RLVITPLTDI
1810 1820 1830 1840 1850
CYITLSQALG MFLGGAPAGP AGTGKTETTK DLGNTLGKYV VVFNCSDQFD
1860 1870 1880 1890 1900
YTYMGKIYKG LAQSGLWGCF DEFNRINLDV LSVCAQQVYC ICRTRERKKS
1910 1920 1930 1940 1950
FQFTDGTTVS LDPRVGFFIT MNPGYAGAQE LPENLKALFR GVTMMVPNRQ
1960 1970 1980 1990 2000
IIMKVKLAAA GYQENDILSK KFFVLYGLCE QQLSKQAHYD FGLRNILSVL
2010 2020 2030 2040 2050
RTAGASKRQS PDKSEVFLMM RTVRDMNMSK FVAEDVPLFL SLIDDLFPGL
2060 2070 2080 2090 2100
KADATRPDVN KDAEKVVLER GLQVHPTWMN KCIQLYETYL VRHGIMLVGP
2110 2120 2130 2140 2150
SGSGKSAICE CLAAALTELG TKHVIWRMNP KAITAPQMFG RRDDTTGDWT
2160 2170 2180 2190 2200
DGIFAVLWRR AAKNKNQNTW IVLDGPVDAI WIENLNTVLD DNKVLTLANG
2210 2220 2230 2240 2250
DRILMSAAMK AMFEPENLNN ASPATVSRAG IIYVSDVELG WEPPVKSWLQ
2260 2270 2280 2290 2300
KRDPTEACWA RLFSKYIDRM LEFVRISLKP VMYNEQVSIV GTVMTLLNGY
2310 2320 2330 2340 2350
LKSMKEAGTA MNDAKYERVF LYCMTWSLGG LLEMKERPLF DQELRTFAHN
2360 2370 2380 2390 2400
MPPKEEDSDT IFEFLVNTTD AEWLHWRHCV PVWTYPKNEE KPQYAQLVIP
2410 2420 2430 2440 2450
TLDSVRYGAL LNLSYNVDKA TLLVGGPGTA KTNTINQFIS KFNAETTANK
2460 2470 2480 2490 2500
TITFSSLTTP GIFQMSIEGA VEKRQGRTFG PPGGKQMCIF VDDISMPYIN
2510 2520 2530 2540 2550
EWGHQVTNEI VRQLLEQGGM YSLEKPIGDM KFITDVRYVA AMNTPGGGKN
2560 2570 2580 2590 2600
DIPNRLKRQF AIFNVPLPSV AAINGIFGKL VEGRFSRDVF CEEVVYVASK
2610 2620 2630 2640 2650
LVPLTITLWN RIQTKMLPTP AKFHYLFNMR ELSKVFQGVI LATRDRFNLA
2660 2670 2680 2690 2700
AGDSAVFGGN VASPEGYLLG LWIHECRRVF SDKLISYEDK NWVDKAVFDL
2710 2720 2730 2740 2750
CRDNFSSDLV KQVEEPIYFV DFLREPAVMM RPVEIVTPHP SFYYSVPGGL
2760 2770 2780 2790 2800
PEVRARVEGL QRKFNEESKV MKLELVLFTD CVTHLMRITR LLAWPGLGLL
2810 2820 2830 2840 2850
VGVGGSGKQS LSRLSAYIAG PTFYITKTYN VSNLFEHIKG LYKIAGFKGQ
2860 2870 2880 2890 2900
PVYFIFTDAE VKDEGFLEYI NQILMTGEVA GLLTKEDQDM IVNDIRPVMK
2910 2920 2930 2940 2950
HQAPGILDTY DNLYNFFLNR VRDNLHVVLC FSPVGAKFAR RAQQFPGLIN
2960 2970 2980 2990 3000
GCTIDWFCPG PKKRLTSVSG KFIDKFTMAC PKEVKNQLEL LMGHAHVFVT
3010 3020 3030 3040 3050
AACKEYFEKY RRYVYVTPKS YLSFLQGYKE LYAKKWSFTK ELAYQIEVAC
3060 3070 3080 3090 3100
QKMFEPKADV NKMKAELAVK NQTAVSAKEA EALLKQISES TAIAEKEKQK
3110 3120 3130 3140 3150
VAVIVDAVTK KASEIATVKD DAERDLAAAK PALDAALEAL NSIKDGDIKN
3160 3170 3180 3190 3200
LKALKKPPQI ITRIFDCVLV LRMLPVTKAE YTDEKGRMVQ VGNYPEAQKM
3210 3220 3230 3240 3250
MNQMSFLQDL KDFAKEQIND ETVELLEPYF MSEDFTFENA QKGSGNVAGL
3260 3270 3280 3290 3300
CNWAESMAKY HNVAKVVEPK IAKLREAEAE LKLATKEKNA AEERMAKVQA
3310 3320 3330 3340 3350
KLDEMQAQFD AAMAHKQALE DDAAATQRKM DSANALIGAL AGEEARWTAQ
3360 3370 3380 3390 3400
SKEFDVQIQR LTGDCALASA FVSYLGPFNK EFRELLLNRD FYGDCMKLNV
3410 3420 3430 3440 3450
PVTPHLQITK FLVDDSEVGE WNLQGLPTDE LSIQNGIMVT RASRYPVLVD
3460 3470 3480 3490 3500
PQGQGREWIK NREEANQLKT TQLNDKLFRN HLEECLAFGR PLLIENIEEE
3510 3520 3530 3540 3550
LDPLLDPVLE RRLVKKGKTW VVPLADKEVD FTETFRLFCT TRLPNPHFTP
3560 3570 3580 3590 3600
ELSAKVTVVD FTVTMAGLED QLLGKLISKE KKELEDQRQQ LLEEVQSYKK
3610 3620 3630 3640 3650
RIKQLEDDLL CRLSNSQGNL LDEHQELIDV LAVTKQTAQD VSEKLANASE
3660 3670 3680 3690 3700
TNKRINEACE EYRPVAHRAT LLYFLIAEFS VVNCMYQTSL AQFNQLYELA
3710 3720 3730 3740 3750
IDRSEKANMP SKRIHNIIEY MTYEIYLYVQ RGLFERHKII FALMLTNKVL
3760 3770 3780 3790 3800
TSAGKVKATD LDVFLKGGAA LDINSVRKKP KDWIPDLVWL NIIALSAMDA
3810 3820 3830 3840 3850
FRDIPDSVFR NDGLWRQWYD QEAPEMAKVP DYEDRLNKFE RMCVVKTFRE
3860 3870 3880 3890 3900
DRTLIAAADY IAEALGQRFV ESVPLNMEKR PGRRAMAKCP LICLLSPGPD
3910 3920 3930 3940 3950
PTKLIEDLAK KKKIKTLGVS MGQGQEVIAR KHMAAASLEG HWVLLQNTHL
3960 3970 3980 3990 4000
GLGYLTEVET FLVKEENVHE DFRLWITAEP HPQFPIGLLQ MGIKITNEAP
4010 4020 4030 4040 4050
VGIKAGLRAS YQWVNQDMLD MVSRQEWRQL LFVMCFLHSV VQEPQFGPIG
4060 4070 4080 4090 4100
WNVPYEFNQS DLSACVQFLQ NHLSEMDAKK APQPTWETVR YMISAIQYGS
4110 4120 4130 4140 4150
RITDDFDKLL MDTFAEKYFL QPVLQPSYEL FKDTRSSDGF SYRVPDSTDI
4160 4170 4180 4190 4200
ETFGSYIETL PGTESPEIFG LHPNADITFR TLQVQESIVT ILDTMPKGAG
4210 4220 4230 4240 4250
SGSGLSREDV VDKICEDLLS KAPPLFDKEE TKEKLKKLPG GPTLPLTVHL
4260 4270 4280 4290 4300
RQEIDRLNIV TRLTTTTLKN LALAIAGTIA AERGLIDALD ALFNARIPQQ
4310 4320 4330 4340 4350
WLSKSWEAST LGNWFTGLLQ RYDQLNKWLN LGRPKAYWMT GFFNPQGFLT
4360 4370 4380 4390 4400
AMKQEVNRKH RDKWALDDVV MSSEVTHRPK DFESLKEGAP EGVYVYGLYL
4410 4420 4430 4440 4450
DLRLDGRENR LMDSDPKKLF NPLPVLHVDG VLAKDKKRSG LYEAPKPYRV
4460 4470 4480
KARKGLNFIT TFSVRTEDDK SKWILPGVGI LCSID
Length:4,485
Mass (Da):512,846
Last modified:November 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i974B79328B403677
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U15303 mRNA Translation: AAA50455.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T08044

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U15303 mRNA Translation: AAA50455.1
PIRiT08044

3D structure databases

SMRiQ39575
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ39575, 2 interactors
STRINGi3055.EDO97301

Proteomic databases

PRIDEiQ39575

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG3595 Eukaryota
COG5245 LUCA

Family and domain databases

Gene3Di1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.20.180.20, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR035699 AAA_6
IPR035706 AAA_9
IPR041658 AAA_lid_11
IPR042219 AAA_lid_11_sf
IPR026983 DHC_fam
IPR041589 DNAH3_AAA_lid_1
IPR042228 Dynein_2_C
IPR042222 Dynein_2_N
IPR041466 Dynein_AAA5_ext
IPR041228 Dynein_C
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_D6_P-loop
IPR013594 Dynein_heavy_dom-1
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PfamiView protein in Pfam
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF17857 AAA_lid_1, 1 hit
PF18198 AAA_lid_11, 1 hit
PF08385 DHC_N1, 1 hit
PF08393 DHC_N2, 1 hit
PF17852 Dynein_AAA_lid, 1 hit
PF18199 Dynein_C, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 3 hits
SUPFAMiSSF52540 SSF52540, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDYHG_CHLRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q39575
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 5, 2019
This is version 85 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again