UniProtKB - Q39442 (VATA_BETVU)
Protein
V-type proton ATPase catalytic subunit A
Gene
N/A
Organism
Beta vulgaris (Sugar beet)
Status
Functioni
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Catalytic activityi
- EC:7.1.2.2
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 252 – 259 | ATPSequence analysis | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- protease binding Source: EnsemblPlants
- proton-transporting ATPase activity, rotational mechanism Source: UniProtKB-EC
- proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-EC
GO - Biological processi
- Golgi organization Source: EnsemblPlants
- pollen development Source: EnsemblPlants
Keywordsi
Molecular function | Translocase |
Biological process | Hydrogen ion transport, Ion transport, Transport |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: V-type proton ATPase catalytic subunit A (EC:7.1.2.2)Short name: V-ATPase subunit A Alternative name(s): V-ATPase 69 kDa subunit Vacuolar proton pump subunit alpha |
Organismi | Beta vulgaris (Sugar beet) |
Taxonomic identifieri | 161934 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › Caryophyllales › Chenopodiaceae › Betoideae › Beta |
Subcellular locationi
Cell Wall
- cell wall Source: EnsemblPlants
Chloroplast
- chloroplast envelope Source: EnsemblPlants
Golgi apparatus
- Golgi apparatus Source: EnsemblPlants
Plasma Membrane
- plasma membrane Source: EnsemblPlants
Vacuole
- plant-type vacuole Source: EnsemblPlants
- vacuolar membrane Source: EnsemblPlants
Other locations
- plasmodesma Source: EnsemblPlants
- proton-transporting V-type ATPase, V1 domain Source: InterPro
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000144575 | 1 – 623 | V-type proton ATPase catalytic subunit AAdd BLAST | 623 |
Proteomic databases
PRIDEi | Q39442 |
Interactioni
Subunit structurei
V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein).
GO - Molecular functioni
- protease binding Source: EnsemblPlants
Family & Domainsi
Sequence similaritiesi
Belongs to the ATPase alpha/beta chains family.Curated
Family and domain databases
Gene3Di | 1.10.1140.10, 1 hit 2.40.30.20, 1 hit |
HAMAPi | MF_00309, ATP_synth_A_arch, 1 hit |
InterProi | View protein in InterPro IPR031686, ATP-synth_a_Xtn IPR023366, ATP_synth_asu-like_sf IPR020003, ATPase_a/bsu_AS IPR004100, ATPase_F1/V1/A1_a/bsu_N IPR036121, ATPase_F1/V1/A1_a/bsu_N_sf IPR000194, ATPase_F1/V1/A1_a/bsu_nucl-bd IPR024034, ATPase_F1/V1_b/a_C IPR005725, ATPase_V1-cplx_asu IPR027417, P-loop_NTPase IPR022878, V-ATPase_asu |
PANTHERi | PTHR43607, PTHR43607, 1 hit |
Pfami | View protein in Pfam PF00006, ATP-synt_ab, 1 hit PF02874, ATP-synt_ab_N, 1 hit PF16886, ATP-synt_ab_Xtn, 1 hit |
SUPFAMi | SSF50615, SSF50615, 1 hit SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR01042, V-ATPase_V1_A, 1 hit |
PROSITEi | View protein in PROSITE PS00152, ATPASE_ALPHA_BETA, 1 hit |
i Sequence
Sequence statusi: Complete.
Q39442-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPAVYGDRMT TFEDSEKESE YGYIRKVSGP VVVADGMNGA AMYELVRVGH
60 70 80 90 100
DNLIGEIIRL EGDSATIQVY EETGGLTVND PVLRTHKPLS VELGPGILGN
110 120 130 140 150
IFDGIQRPLK TIAKRSGDVY IPRGVSVPPL DKDTQWDFQP KKLGVGDLLT
160 170 180 190 200
GGDLYAIVDE NSLMQHHVVL PPDAMGKITY IAPAGNYTIQ DTVLELEFQG
210 220 230 240 250
VVKKFTMLQT WPVRTPRPVA SKLAADTPLL TGQRVLDALF PSVLGGTCAI
260 270 280 290 300
LGAFGCGKTV ISQALSKYSN SDAVVYVGCG ERGNEMAEVL MDFPQLTMTL
310 320 330 340 350
PDGREESVMK RTTLVANTSN MPVAAREASI YTGITIAEYF RDMGYNVSMM
360 370 380 390 400
ADSGSRWAEA LREISGRLAE MPADSGYPAY LAARLASFYE AAGKVKCLGG
410 420 430 440 450
PERNGSVTIV GAVSPPGGDF SDPVTSATLS IVQVFWGLDK KLAQRKHFPS
460 470 480 490 500
VNWLISYSKY SGALESFYEK FDSEFIDIRT KAREVLQRED DLNEIVQLVG
510 520 530 540 550
KDALAETDKI TLDTAKLLRE DYLAQNAFTA YDKFCPFYKS VWMMRNIIHF
560 570 580 590 600
YNLANQAVER GAGSDGQKIT YSLIKLRLGD LFYRLVSQKF EDPAEGEDAL
610 620
VAKFKKLNED LTAAFRNLED ETR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X98767 mRNA Translation: CAA67305.1 |
RefSeqi | NP_001290002.1, NM_001303073.1 |
Genome annotation databases
GeneIDi | 104906090 |
KEGGi | bvg:104906090 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X98767 mRNA Translation: CAA67305.1 |
RefSeqi | NP_001290002.1, NM_001303073.1 |
3D structure databases
SMRi | Q39442 |
ModBasei | Search... |
Proteomic databases
PRIDEi | Q39442 |
Genome annotation databases
GeneIDi | 104906090 |
KEGGi | bvg:104906090 |
Family and domain databases
Gene3Di | 1.10.1140.10, 1 hit 2.40.30.20, 1 hit |
HAMAPi | MF_00309, ATP_synth_A_arch, 1 hit |
InterProi | View protein in InterPro IPR031686, ATP-synth_a_Xtn IPR023366, ATP_synth_asu-like_sf IPR020003, ATPase_a/bsu_AS IPR004100, ATPase_F1/V1/A1_a/bsu_N IPR036121, ATPase_F1/V1/A1_a/bsu_N_sf IPR000194, ATPase_F1/V1/A1_a/bsu_nucl-bd IPR024034, ATPase_F1/V1_b/a_C IPR005725, ATPase_V1-cplx_asu IPR027417, P-loop_NTPase IPR022878, V-ATPase_asu |
PANTHERi | PTHR43607, PTHR43607, 1 hit |
Pfami | View protein in Pfam PF00006, ATP-synt_ab, 1 hit PF02874, ATP-synt_ab_N, 1 hit PF16886, ATP-synt_ab_Xtn, 1 hit |
SUPFAMi | SSF50615, SSF50615, 1 hit SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR01042, V-ATPase_V1_A, 1 hit |
PROSITEi | View protein in PROSITE PS00152, ATPASE_ALPHA_BETA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | VATA_BETVU | |
Accessioni | Q39442Primary (citable) accession number: Q39442 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | December 2, 2020 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |