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UniProtKB - Q39233 (SYP21_ARATH)
Protein
Syntaxin-21
Gene
SYP21
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
May function in the docking or fusion of transport vesicles with the prevacuolar membrane.
GO - Molecular functioni
- SNAP receptor activity Source: TAIR
- SNARE binding Source: GO_Central
GO - Biological processi
- Golgi to vacuole transport Source: TAIR
- intracellular protein transport Source: GO_Central
- late endosome to vacuole transport Source: TAIR
- protein targeting to vacuole Source: TAIR
- vesicle docking Source: GO_Central
- vesicle fusion Source: GO_Central
Keywordsi
Biological process | Protein transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Syntaxin-21Short name: AtSYP21 Alternative name(s): PEP12 homolog Short name: AtPEP12 aPEP12 |
Gene namesi | Name:SYP21 Ordered Locus Names:At5g16830 ORF Names:F5E19_170 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G16830 |
TAIRi | locus:2148960, AT5G16830 |
Subcellular locationi
Other locations
- Prevacuolar compartment membrane 1 Publication; Single-pass type IV membrane protein 1 Publication
Endosome
- late endosome Source: TAIR
Other locations
- endomembrane system Source: GO_Central
- integral component of membrane Source: GO_Central
- membrane Source: TAIR
- SNARE complex Source: GO_Central
- trans-Golgi network transport vesicle Source: TAIR
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 2 – 258 | CytoplasmicSequence analysisAdd BLAST | 257 | |
Transmembranei | 259 – 279 | Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000210253 | 2 – 279 | Syntaxin-21Add BLAST | 278 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylserineBy similarity | 1 |
Keywords - PTMi
AcetylationProteomic databases
PaxDbi | Q39233 |
ProteomicsDBi | 228470 |
PTM databases
SwissPalmi | Q39233 |
Expressioni
Tissue specificityi
A high level expression is seen in the roots while a low level expression is seen in the leaves.
Gene expression databases
ExpressionAtlasi | Q39233, baseline and differential |
Genevisiblei | Q39233, AT |
Interactioni
Subunit structurei
Interacts with VTI11 and SYP51 to form a t-SNARE complex and with alpha-SNAP to form a 20S complex.
2 PublicationsBinary interactionsi
Q39233
With | #Exp. | IntAct |
---|---|---|
VTI11 [Q9SEL6] | 4 | EBI-2352544,EBI-1162795 |
GO - Molecular functioni
- SNARE binding Source: GO_Central
Protein-protein interaction databases
BioGRIDi | 16822, 54 interactors |
IntActi | Q39233, 52 interactors |
STRINGi | 3702.AT5G16830.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 186 – 248 | t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST | 63 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 34 | DisorderedSequence analysisAdd BLAST | 34 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 65 – 94 | Sequence analysisAdd BLAST | 30 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 16 – 31 | Polar residuesSequence analysisAdd BLAST | 16 |
Sequence similaritiesi
Belongs to the syntaxin family.Curated
Keywords - Domaini
Coiled coil, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0811, Eukaryota |
HOGENOMi | CLU_059257_3_0_1 |
InParanoidi | Q39233 |
OMAi | YNAPELD |
OrthoDBi | 1204812at2759 |
PhylomeDBi | Q39233 |
Family and domain databases
CDDi | cd00179, SynN, 1 hit |
InterProi | View protein in InterPro IPR010989, SNARE IPR045242, Syntaxin IPR006012, Syntaxin/epimorphin_CS IPR006011, Syntaxin_N IPR000727, T_SNARE_dom |
PANTHERi | PTHR19957, PTHR19957, 1 hit |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit PF14523, Syntaxin_2, 1 hit |
SMARTi | View protein in SMART SM00503, SynN, 1 hit SM00397, t_SNARE, 1 hit |
SUPFAMi | SSF47661, SSF47661, 1 hit |
PROSITEi | View protein in PROSITE PS00914, SYNTAXIN, 1 hit PS50192, T_SNARE, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q39233-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSFQDLEAGT RSPAPNRFTG GRQQRPSSRG DPSQEVAAGI FRISTAVNSF
60 70 80 90 100
FRLVNSIGTP KDTLELRDKL QKTRLQISEL VKNTSAKLKE ASEADLHGSA
110 120 130 140 150
SQIKKIADAK LAKDFQSVLK EFQKAQRLAA EREITYTPVV TKEIPTSYNA
160 170 180 190 200
PELDTESLRI SQQQALLLQS RRQEVVFLDN EITFNEAIIE EREQGIREIE
210 220 230 240 250
DQIRDVNGMF KDLALMVNHQ GNIVDDISSN LDNSHAATTQ ATVQLRKAAK
260 270
TQRSNSSLTC LLILIFGIVL LIVIIVVLV
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 14 | A → T in AAM66128 (Ref. 5) Curated | 1 | |
Sequence conflicti | 263 | I → T in AAM66128 (Ref. 5) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L41651 mRNA Translation: AAA87296.1 AL391147 Genomic DNA Translation: CAC01847.1 CP002688 Genomic DNA Translation: AED92345.1 AF411797 mRNA Translation: AAL06486.1 AY088599 mRNA Translation: AAM66128.1 |
PIRi | T51515 |
RefSeqi | NP_197185.1, NM_121689.4 |
Genome annotation databases
EnsemblPlantsi | AT5G16830.1; AT5G16830.1; AT5G16830 |
GeneIDi | 831546 |
Gramenei | AT5G16830.1; AT5G16830.1; AT5G16830 |
KEGGi | ath:AT5G16830 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L41651 mRNA Translation: AAA87296.1 AL391147 Genomic DNA Translation: CAC01847.1 CP002688 Genomic DNA Translation: AED92345.1 AF411797 mRNA Translation: AAL06486.1 AY088599 mRNA Translation: AAM66128.1 |
PIRi | T51515 |
RefSeqi | NP_197185.1, NM_121689.4 |
3D structure databases
AlphaFoldDBi | Q39233 |
SMRi | Q39233 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 16822, 54 interactors |
IntActi | Q39233, 52 interactors |
STRINGi | 3702.AT5G16830.1 |
PTM databases
SwissPalmi | Q39233 |
Proteomic databases
PaxDbi | Q39233 |
ProteomicsDBi | 228470 |
Genome annotation databases
EnsemblPlantsi | AT5G16830.1; AT5G16830.1; AT5G16830 |
GeneIDi | 831546 |
Gramenei | AT5G16830.1; AT5G16830.1; AT5G16830 |
KEGGi | ath:AT5G16830 |
Organism-specific databases
Araporti | AT5G16830 |
TAIRi | locus:2148960, AT5G16830 |
Phylogenomic databases
eggNOGi | KOG0811, Eukaryota |
HOGENOMi | CLU_059257_3_0_1 |
InParanoidi | Q39233 |
OMAi | YNAPELD |
OrthoDBi | 1204812at2759 |
PhylomeDBi | Q39233 |
Miscellaneous databases
PROi | PR:Q39233 |
Gene expression databases
ExpressionAtlasi | Q39233, baseline and differential |
Genevisiblei | Q39233, AT |
Family and domain databases
CDDi | cd00179, SynN, 1 hit |
InterProi | View protein in InterPro IPR010989, SNARE IPR045242, Syntaxin IPR006012, Syntaxin/epimorphin_CS IPR006011, Syntaxin_N IPR000727, T_SNARE_dom |
PANTHERi | PTHR19957, PTHR19957, 1 hit |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit PF14523, Syntaxin_2, 1 hit |
SMARTi | View protein in SMART SM00503, SynN, 1 hit SM00397, t_SNARE, 1 hit |
SUPFAMi | SSF47661, SSF47661, 1 hit |
PROSITEi | View protein in PROSITE PS00914, SYNTAXIN, 1 hit PS50192, T_SNARE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SYP21_ARATH | |
Accessioni | Q39233Primary (citable) accession number: Q39233 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1996 | |
Last modified: | May 25, 2022 | |
This is version 154 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families