UniProtKB - Q38IW3 (Q38IW3_XENTR)
Protein
Submitted name:
Alpha globin larval-3
Gene
HBA-L3
Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 59 | Iron (heme distal ligand)PROSITE-ProRule annotation | 1 | |
Metal bindingi | 88 | Iron (heme proximal ligand)PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- heme binding Source: GO_Central
- iron ion binding Source: InterPro
- organic acid binding Source: GO_Central
- oxygen binding Source: GO_Central
- oxygen carrier activity Source: GO_Central
GO - Biological processi
- cellular oxidant detoxification Source: GOC
- hydrogen peroxide catabolic process Source: GO_Central
Keywordsi
Biological process | Oxygen transportPROSITE-ProRule annotationARBA annotation, Transport |
Ligand | HemePROSITE-ProRule annotationARBA annotation, Iron, Metal-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Alpha globin larval-3Imported |
Gene namesi | Name:HBA-L3Imported Synonyms:hba-l5Imported |
Organismi | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported |
Taxonomic identifieri | 8364 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana |
Proteomesi |
|
Subcellular locationi
Cytosol
- hemoglobin complex Source: GO_Central
Other locations
- haptoglobin-hemoglobin complex Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSXETG00000029988, Expressed in embryo and 2 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 3 – 142 | GLOBINInterPro annotationAdd BLAST | 140 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG3378, Eukaryota |
GeneTreei | ENSGT00940000158623 |
HOGENOMi | CLU_003827_10_2_1 |
OMAi | HEHAQNS |
OrthoDBi | 1398217at2759 |
TreeFami | TF332328 |
Family and domain databases
CDDi | cd08927, Hb-alpha_like, 1 hit |
Gene3Di | 1.10.490.10, 1 hit |
InterProi | View protein in InterPro IPR000971, Globin IPR009050, Globin-like_sf IPR012292, Globin/Proto IPR002338, Haemoglobin_a-typ IPR002339, Haemoglobin_pi |
Pfami | View protein in Pfam PF00042, Globin, 1 hit |
PRINTSi | PR00612, ALPHAHAEM PR00815, PIHAEM |
SUPFAMi | SSF46458, SSF46458, 1 hit |
PROSITEi | View protein in PROSITE PS01033, GLOBIN, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
Q38IW3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLLSDAEKAA VVSLWAKASG SVNALGAEAL ERLFLSYPQT KTYFSHFDLS
60 70 80 90 100
SGSHDLQVHG GKVLGAIGEA TKHLDNLDEA LSKLSDLHAY NLRVDPGNFR
110 120 130 140
LLSHTIQVTL AAHFQAEFDA TAQAAWDKYL AAISTVLTSK YR
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ38IW2 | Q38IW2_XENTR | Alpha globin larval-4 | HBA-L4 hba-l5 | 142 | Annotation score: | ||
Q38IW1 | Q38IW1_XENTR | Alpha globin larval-5 | hba-l5 HBA-L5, TTpA018o08.1-001 | 142 | Annotation score: | ||
A0A5G3HDA8 | A0A5G3HDA8_XENTR | GLOBIN domain-containing protein | hba-l5 | 142 | Annotation score: | ||
A0A6I8RT00 | A0A6I8RT00_XENTR | GLOBIN domain-containing protein | hba-l5 | 142 | Annotation score: | ||
Q38IW4 | Q38IW4_XENTR | Alpha globin larval-2 | HBA-L2 hba-l5, LOC100135125 | 142 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ224413 Genomic DNA Translation: ABB04100.1 |
RefSeqi | NP_001165373.1, NM_001171902.1 |
Genome annotation databases
Ensembli | ENSXETT00000074185; ENSXETP00000088099; ENSXETG00000030564 |
GeneIDi | 100335042 |
KEGGi | xtr:100335042 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ224413 Genomic DNA Translation: ABB04100.1 |
RefSeqi | NP_001165373.1, NM_001171902.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 8364.ENSXETP00000002493 |
Genome annotation databases
Ensembli | ENSXETT00000074185; ENSXETP00000088099; ENSXETG00000030564 |
GeneIDi | 100335042 |
KEGGi | xtr:100335042 |
Organism-specific databases
CTDi | 100335042 |
Phylogenomic databases
eggNOGi | KOG3378, Eukaryota |
GeneTreei | ENSGT00940000158623 |
HOGENOMi | CLU_003827_10_2_1 |
OMAi | HEHAQNS |
OrthoDBi | 1398217at2759 |
TreeFami | TF332328 |
Gene expression databases
Bgeei | ENSXETG00000029988, Expressed in embryo and 2 other tissues |
Family and domain databases
CDDi | cd08927, Hb-alpha_like, 1 hit |
Gene3Di | 1.10.490.10, 1 hit |
InterProi | View protein in InterPro IPR000971, Globin IPR009050, Globin-like_sf IPR012292, Globin/Proto IPR002338, Haemoglobin_a-typ IPR002339, Haemoglobin_pi |
Pfami | View protein in Pfam PF00042, Globin, 1 hit |
PRINTSi | PR00612, ALPHAHAEM PR00815, PIHAEM |
SUPFAMi | SSF46458, SSF46458, 1 hit |
PROSITEi | View protein in PROSITE PS01033, GLOBIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q38IW3_XENTR | |
Accessioni | Q38IW3Primary (citable) accession number: Q38IW3 Secondary accession number(s): F7BFF1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 22, 2005 |
Last sequence update: | November 22, 2005 | |
Last modified: | December 2, 2020 | |
This is version 104 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |