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Protein

Ras-related protein RABB1b

Gene

RABB1B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Intracellular vesicle trafficking and protein transport.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 20GTPBy similarity8
Nucleotide bindingi61 – 65GTPBy similarity5
Nucleotide bindingi119 – 122GTPBy similarity4
Nucleotide bindingi149 – 150GTPBy similarity2

GO - Molecular functioni

  • GTPase activity Source: InterPro
  • GTP binding Source: TAIR

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-8873719 RAB geranylgeranylation

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein RABB1b
Short name:
AtRABB1b
Alternative name(s):
Ras-related protein GB2
Short name:
AtGB2
Ras-related protein Rab2C
Short name:
AtRab2C
Gene namesi
Name:RABB1B
Synonyms:GB2, RAB2C
Ordered Locus Names:At4g35860
ORF Names:F4B14.130
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G35860
TAIRilocus:2125384 AT4G35860

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004073551 – 211Ras-related protein RABB1bAdd BLAST211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi209S-geranylgeranyl cysteineBy similarity1
Lipidationi210S-geranylgeranyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Prenylation

Proteomic databases

PaxDbiQ38922
PRIDEiQ38922

Expressioni

Gene expression databases

ExpressionAtlasiQ38922 baseline and differential
GenevisibleiQ38922 AT

Interactioni

Protein-protein interaction databases

BioGridi15022, 13 interactors
IntActiQ38922, 12 interactors
STRINGi3702.AT4G35860.1

Structurei

3D structure databases

ProteinModelPortaliQ38922
SMRiQ38922
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi35 – 43Effector regionBy similarity9

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiKOG0098 Eukaryota
COG1100 LUCA
HOGENOMiHOG000233968
InParanoidiQ38922
OMAiYGRPQGP
OrthoDBiEOG09360MD2
PhylomeDBiQ38922

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51419 RAB, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q38922-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSYDYLFKYI IIGDTGVGKS CLLLQFTDKR FQPVHDLTIG VEFGARMVTV
60 70 80 90 100
DGRPIKLQIW DTAGQESFRS ITRSYYRGAA GALLVYDITR RETFNHLASW
110 120 130 140 150
LEDARQHANP NMSIMLIGNK CDLAHKRAVS KEEGQQFAKE HGLLFLEASA
160 170 180 190 200
RTAQNVEEAF IETAAKILQN IQDGVFDVSN ESSGIKIGYG RTQGAAGGRD
210
GTISQGGGCC G
Length:211
Mass (Da):23,175
Last modified:November 1, 1996 - v1
Checksum:i71B5036D4B9A158E
GO
Isoform 2 (identifier: Q38922-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-46: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:165
Mass (Da):17,936
Checksum:iC48B3699CA23CA17
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0409461 – 46Missing in isoform 2. CuratedAdd BLAST46

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U46925 mRNA Translation: AAA87883.1
AL031986 Genomic DNA Translation: CAA21472.1
AL161588 Genomic DNA Translation: CAB81495.1
CP002687 Genomic DNA Translation: AEE86581.1
CP002687 Genomic DNA Translation: AEE86582.1
AY065262 mRNA Translation: AAL38738.1
AY117348 mRNA Translation: AAM51423.1
AY085750 mRNA Translation: AAM62968.1
PIRiS71585
RefSeqiNP_001078499.1, NM_001085030.1 [Q38922-3]
NP_195311.1, NM_119752.4 [Q38922-1]
UniGeneiAt.2486
At.70211

Genome annotation databases

EnsemblPlantsiAT4G35860.1; AT4G35860.1; AT4G35860 [Q38922-1]
AT4G35860.2; AT4G35860.2; AT4G35860 [Q38922-3]
GeneIDi829740
GrameneiAT4G35860.1; AT4G35860.1; AT4G35860 [Q38922-1]
AT4G35860.2; AT4G35860.2; AT4G35860 [Q38922-3]
KEGGiath:AT4G35860

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiRAB1B_ARATH
AccessioniPrimary (citable) accession number: Q38922
Secondary accession number(s): A8MRA2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: November 1, 1996
Last modified: July 18, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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