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Protein

Rac-like GTP-binding protein ARAC1

Gene

ARAC1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 20GTPBy similarity8
Nucleotide bindingi60 – 64GTPBy similarity5
Nucleotide bindingi118 – 121GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

  • abscisic acid-activated signaling pathway Source: TAIR
  • auxin-activated signaling pathway Source: TAIR
  • small GTPase mediated signal transduction Source: InterPro

Keywordsi

LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-194840 Rho GTPase cycle
R-ATH-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Rac-like GTP-binding protein ARAC1
Alternative name(s):
GTPase protein ROP3
Gene namesi
Name:ARAC1
Synonyms:ATGP2, ROP3
Ordered Locus Names:At2g17800
ORF Names:T17A5.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G17800
TAIRilocus:2827916 AT2G17800

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001989151 – 194Rac-like GTP-binding protein ARAC1Add BLAST194
PropeptideiPRO_0000227580195 – 197Removed in mature formSequence analysis3

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei194Cysteine methyl esterSequence analysis1
Lipidationi194S-geranylgeranyl cysteineSequence analysis1

Keywords - PTMi

Lipoprotein, Methylation, Prenylation

Proteomic databases

PaxDbiQ38902
PRIDEiQ38902

Expressioni

Tissue specificityi

Ubiquitous.1 Publication

Gene expression databases

ExpressionAtlasiQ38902 baseline and differential
GenevisibleiQ38902 AT

Interactioni

Subunit structurei

Interacts with SPK1.1 Publication

Protein-protein interaction databases

BioGridi1647, 5 interactors
DIPiDIP-29819N
IntActiQ38902, 3 interactors
STRINGi3702.AT2G17800.1

Structurei

3D structure databases

ProteinModelPortaliQ38902
SMRiQ38902
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi35 – 43Effector regionSequence analysis9

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi182 – 189Poly-Lys8

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rho family.Curated

Phylogenomic databases

eggNOGiKOG0393 Eukaryota
COG1100 LUCA
HOGENOMiHOG000233974
InParanoidiQ38902
KOiK04392
OMAiPLCYTNA
OrthoDBiEOG09360LB1
PhylomeDBiQ38902

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51420 RHO, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q38902-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASRFIKCV TVGDGAVGKT CLLISYTSNT FPTDYVPTVF DNFSANVVVN
60 70 80 90 100
GATVNLGLWD TAGQEDYNRL RPLSYRGADV FILAFSLISK ASYENVSKKW
110 120 130 140 150
IPELKHYAPG VPIVLVGTKL DLRDDKQFFI DHPGAVPITT AQGEELKKLI
160 170 180 190
GAPAYIECSS KTQENVKGVF DAAIRVVLQP PKQKKKKSKA QKACSIL
Length:197
Mass (Da):21,530
Last modified:November 1, 1997 - v1
Checksum:iC566CFC0C4390632
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U64919 mRNA Translation: AAD00113.1
U41295 mRNA Translation: AAC49851.1
AF115466 Genomic DNA Translation: AAF40237.1
CP002685 Genomic DNA Translation: AEC06689.1
CP002685 Genomic DNA Translation: AEC06690.1
AY093046 mRNA Translation: AAM13045.1
BT000393 mRNA Translation: AAN15712.1
PIRiT08857
RefSeqiNP_001077910.1, NM_001084441.2
NP_179371.1, NM_127334.4
UniGeneiAt.23460

Genome annotation databases

EnsemblPlantsiAT2G17800.1; AT2G17800.1; AT2G17800
AT2G17800.2; AT2G17800.2; AT2G17800
GeneIDi816290
GrameneiAT2G17800.1; AT2G17800.1; AT2G17800
AT2G17800.2; AT2G17800.2; AT2G17800
KEGGiath:AT2G17800

Similar proteinsi

Entry informationi

Entry nameiRAC1_ARATH
AccessioniPrimary (citable) accession number: Q38902
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 18, 2018
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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