UniProtKB - Q38847 (AGL15_ARATH)
Agamous-like MADS-box protein AGL15
AGL15
Functioni
Transcription factor involved in the negative regulation of flowering, probably through the photoperiodic pathway. Acts as both an activator and a repressor of transcription. Binds DNA in a sequence-specific manner in large CArG motif 5'-CC (A/T)8 GG-3'. Participates probably in the regulation of programs active during the early stages of embryo development. Prevents premature perianth senescence and abscission, fruits development and seed desiccation. Stimulates the expression of at least DTA4, LEC2, FUS3, ABI3, AT4G38680/CSP2 and GRP2B/CSP4. Can enhance somatic embryo development in vitro.
12 PublicationsGO - Molecular functioni
- DNA binding Source: UniProtKB
- DNA-binding transcription factor activity Source: TAIR
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- protein homodimerization activity Source: UniProtKB
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: TAIR
GO - Biological processi
- cellular response to auxin stimulus Source: UniProtKB
- embryo development ending in seed dormancy Source: TAIR
- floral organ abscission Source: TAIR
- fruit abscission Source: UniProtKB
- fruit dehiscence Source: UniProtKB
- gibberellin catabolic process Source: TAIR
- negative regulation of floral organ abscission Source: UniProtKB
- negative regulation of flower development Source: UniProtKB
- negative regulation of gene expression Source: TAIR
- negative regulation of seed maturation Source: UniProtKB
- negative regulation of short-day photoperiodism, flowering Source: UniProtKB
- negative regulation of transcription, DNA-templated Source: UniProtKB
- positive regulation of transcription, DNA-templated Source: UniProtKB
- positive regulation of transcription by RNA polymerase II Source: InterPro
- regulation of transcription by RNA polymerase II Source: GO_Central
- somatic embryogenesis Source: UniProtKB
Keywordsi
Molecular function | Activator, Developmental protein, DNA-binding, Repressor |
Biological process | Flowering, Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Agamous-like MADS-box protein AGL15 |
Gene namesi | Name:AGL15 Ordered Locus Names:At5g13790 ORF Names:MXE10.6 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G13790 |
TAIRi | locus:2177125, AT5G13790 |
Pathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000199474 | 1 – 268 | Agamous-like MADS-box protein AGL15Add BLAST | 268 |
Proteomic databases
PaxDbi | Q38847 |
ProteomicsDBi | 244678 |
Expressioni
Tissue specificityi
Developmental stagei
Inductioni
Gene expression databases
ExpressionAtlasi | Q38847, baseline and differential |
Genevisiblei | Q38847, AT |
Interactioni
Subunit structurei
Homodimer.
Interacts with SVP, AGL24, AP1, AGL6, AG, AGL1, AGL11, AGL5, AGL16, SOC1 and AGL21.
1 PublicationBinary interactionsi
Q38847
With | #Exp. | IntAct |
---|---|---|
AGL21 [Q9SZJ6] | 5 | EBI-622076,EBI-621986 |
GO - Molecular functioni
- protein homodimerization activity Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 16502, 45 interactors |
IntActi | Q38847, 23 interactors |
STRINGi | 3702.AT5G13790.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 61 | MADS-boxPROSITE-ProRule annotationAdd BLAST | 61 | |
Domaini | 80 – 170 | K-boxPROSITE-ProRule annotationAdd BLAST | 91 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 205 – 268 | DisorderedSequence analysisAdd BLAST | 64 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 231 – 268 | Polar residuesSequence analysisAdd BLAST | 38 |
Phylogenomic databases
eggNOGi | KOG0014, Eukaryota |
HOGENOMi | CLU_053053_0_2_1 |
PhylomeDBi | Q38847 |
Family and domain databases
CDDi | cd00265, MADS_MEF2_like, 1 hit |
Gene3Di | 3.40.1810.10, 1 hit |
InterProi | View protein in InterPro IPR033896, MADS_MEF2-like IPR002487, TF_Kbox IPR002100, TF_MADSbox IPR036879, TF_MADSbox_sf |
Pfami | View protein in Pfam PF01486, K-box, 1 hit PF00319, SRF-TF, 1 hit |
PRINTSi | PR00404, MADSDOMAIN |
SMARTi | View protein in SMART SM00432, MADS, 1 hit |
SUPFAMi | SSF55455, SSF55455, 1 hit |
PROSITEi | View protein in PROSITE PS51297, K_BOX, 1 hit PS00350, MADS_BOX_1, 1 hit PS50066, MADS_BOX_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
10 20 30 40 50
MGRGKIEIKR IENANSRQVT FSKRRSGLLK KARELSVLCD AEVAVIVFSK
60 70 80 90 100
SGKLFEYSST GMKQTLSRYG NHQSSSASKA EEDCAEVDIL KDQLSKLQEK
110 120 130 140 150
HLQLQGKGLN PLTFKELQSL EQQLYHALIT VRERKERLLT NQLEESRLKE
160 170 180 190 200
QRAELENETL RRQVQELRSF LPSFTHYVPS YIKCFAIDPK NALINHDSKC
210 220 230 240 250
SLQNTDSDTT LQLGLPGEAH DRRTNEGERE SPSSDSVTTN TSSETAERGD
260
QSSLANSPPE AKRQRFSV
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A178UBU5 | A0A178UBU5_ARATH | AGAMOUS-like 15 | AGL15 AGAMOUS-like 15, MADS-BOX PROTEIN AGL15, MXE10.8, MXE10_8, At5g13790 | 271 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U22528 Genomic DNA Translation: AAA65653.1 AB011484, AB005230 Genomic DNA Translation: BAB10600.1 CP002688 Genomic DNA Translation: AED91941.1 U20185 mRNA Translation: AAC49083.1 |
PIRi | S71200 |
RefSeqi | NP_196883.1, NM_121382.3 |
Genome annotation databases
EnsemblPlantsi | AT5G13790.1; AT5G13790.1; AT5G13790 |
GeneIDi | 831224 |
Gramenei | AT5G13790.1; AT5G13790.1; AT5G13790 |
KEGGi | ath:AT5G13790 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U22528 Genomic DNA Translation: AAA65653.1 AB011484, AB005230 Genomic DNA Translation: BAB10600.1 CP002688 Genomic DNA Translation: AED91941.1 U20185 mRNA Translation: AAC49083.1 |
PIRi | S71200 |
RefSeqi | NP_196883.1, NM_121382.3 |
3D structure databases
AlphaFoldDBi | Q38847 |
SMRi | Q38847 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 16502, 45 interactors |
IntActi | Q38847, 23 interactors |
STRINGi | 3702.AT5G13790.1 |
Proteomic databases
PaxDbi | Q38847 |
ProteomicsDBi | 244678 |
Genome annotation databases
EnsemblPlantsi | AT5G13790.1; AT5G13790.1; AT5G13790 |
GeneIDi | 831224 |
Gramenei | AT5G13790.1; AT5G13790.1; AT5G13790 |
KEGGi | ath:AT5G13790 |
Organism-specific databases
Araporti | AT5G13790 |
TAIRi | locus:2177125, AT5G13790 |
Phylogenomic databases
eggNOGi | KOG0014, Eukaryota |
HOGENOMi | CLU_053053_0_2_1 |
PhylomeDBi | Q38847 |
Miscellaneous databases
PROi | PR:Q38847 |
Gene expression databases
ExpressionAtlasi | Q38847, baseline and differential |
Genevisiblei | Q38847, AT |
Family and domain databases
CDDi | cd00265, MADS_MEF2_like, 1 hit |
Gene3Di | 3.40.1810.10, 1 hit |
InterProi | View protein in InterPro IPR033896, MADS_MEF2-like IPR002487, TF_Kbox IPR002100, TF_MADSbox IPR036879, TF_MADSbox_sf |
Pfami | View protein in Pfam PF01486, K-box, 1 hit PF00319, SRF-TF, 1 hit |
PRINTSi | PR00404, MADSDOMAIN |
SMARTi | View protein in SMART SM00432, MADS, 1 hit |
SUPFAMi | SSF55455, SSF55455, 1 hit |
PROSITEi | View protein in PROSITE PS51297, K_BOX, 1 hit PS00350, MADS_BOX_1, 1 hit PS50066, MADS_BOX_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | AGL15_ARATH | |
Accessioni | Q38847Primary (citable) accession number: Q38847 Secondary accession number(s): Q38839 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 15, 1998 |
Last sequence update: | November 1, 1996 | |
Last modified: | May 25, 2022 | |
This is version 158 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names