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Protein

Auxin-responsive protein IAA10

Gene

IAA10

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.1 Publication

GO - Molecular functioni

  • DNA binding transcription factor activity Source: TAIR

GO - Biological processi

  • auxin-activated signaling pathway Source: UniProtKB-KW
  • response to auxin Source: TAIR
  • response to chitin Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionRepressor
Biological processAuxin signaling pathway, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Auxin-responsive protein IAA10
Alternative name(s):
Indoleacetic acid-induced protein 10
Gene namesi
Name:IAA10
Ordered Locus Names:At1g04100
ORF Names:F20D22.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G04100
TAIRilocus:2020255 AT1G04100

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001128411 – 261Auxin-responsive protein IAA10Add BLAST261

Proteomic databases

PaxDbiQ38828
PRIDEiQ38828

Expressioni

Tissue specificityi

Preferentially expressed in vegetative organs.1 Publication

Inductioni

By auxin.1 Publication

Gene expression databases

ExpressionAtlasiQ38828 baseline and differential
GenevisibleiQ38828 AT

Interactioni

Subunit structurei

Homodimers and heterodimers.By similarity

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi24525, 34 interactors
ELMiQ38828
IntActiQ38828, 47 interactors
STRINGi3702.AT1G04100.1

Structurei

3D structure databases

ProteinModelPortaliQ38828
SMRiQ38828
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini151 – 253PB1PROSITE-ProRule annotationAdd BLAST103

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi45 – 49EAR-like (transcriptional repression)5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi60 – 68Poly-Ser9

Domaini

The N-terminal half of the protein contains two conserved domains I and II. Domain I includes a slightly degenerated ERF-associated amphiphilic repression (EAR) motif which seems to be involved in the activity of transcriptional repression. Domain II is required for the correct degradation of the protein through the SCF-mediated ubiquitin-proteasome pathway. Interactions between Aux/IAA proteins and auxin response factors (ARFs) occur through their C-terminal dimerization domains III and IV.

Sequence similaritiesi

Belongs to the Aux/IAA family.Curated

Phylogenomic databases

eggNOGiENOG410JTJU Eukaryota
ENOG41107SC LUCA
HOGENOMiHOG000238261
InParanoidiQ38828
KOiK14484
OMAiFRDVCSS
OrthoDBiEOG09360MNU
PhylomeDBiQ38828

Family and domain databases

InterProiView protein in InterPro
IPR033389 AUX/IAA_dom
IPR003311 AUX_IAA
IPR000270 PB1_dom
PANTHERiPTHR31734 PTHR31734, 1 hit
PfamiView protein in Pfam
PF02309 AUX_IAA, 1 hit
PROSITEiView protein in PROSITE
PS51745 PB1, 1 hit

Sequencei

Sequence statusi: Complete.

Q38828-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGLQEVCSS SGSVMIGLPA EEDENAAHSS EDSSCPDESV SETELDLALG
60 70 80 90 100
LSIGRRKVRS SLSSSSSSLT RESGTKRSAD SSPAAASNAT RQVAVGWPPL
110 120 130 140 150
RTYRINSLVN QAKSLATEGG LSSGIQKETT KSVVVAAKND DACFIKSSRT
160 170 180 190 200
SMLVKVTMDG VIIGRKVDLN ALDSYAALEK TLDLMFFQIP SPVTRSNTQG
210 220 230 240 250
YKTIKETCTS KLLDGSSEYI ITYQDKDGDW MLVGDVPWQM FLGSVTRLRI
260
MKTSIGAGVG K
Length:261
Mass (Da):27,878
Last modified:November 1, 1996 - v1
Checksum:iDE99194344815A14
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18412 mRNA Translation: AAC49051.1
AC002411 Genomic DNA Translation: AAC16750.1
CP002684 Genomic DNA Translation: AEE27656.1
AF332396 mRNA Translation: AAG48760.1
PIRiS58496
RefSeqiNP_171906.1, NM_100291.3
UniGeneiAt.21582

Genome annotation databases

EnsemblPlantsiAT1G04100.1; AT1G04100.1; AT1G04100
GeneIDi839290
GrameneiAT1G04100.1; AT1G04100.1; AT1G04100
KEGGiath:AT1G04100

Similar proteinsi

Entry informationi

Entry nameiIAA10_ARATH
AccessioniPrimary (citable) accession number: Q38828
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: April 25, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

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