UniProtKB - Q38167 (DMP_BPT5)
Functioni
Following host DNA degradation, is responsible for the degradation of 5'-dNMP's to deoxynucleosides that can be further excreted (PubMed:335083). Active on deoxynucleoside 5'-monophosphates but not active as a phosphatase on ribonucleotides, deoxynucleoside 5'-triphosphates, deoxynucleoside 3'-monophosphates, or deoxyoligonucleotides (PubMed:21305).2 Publications
Miscellaneous
This gene is part of the long terminal repeats present at both ends of the viral genome and is thus duplicated.1 Publication
Catalytic activityi
- EC:3.1.3.89
GO - Molecular functioni
- hydrolase activity Source: UniProtKB-KW
GO - Biological processi
- catabolism by virus of host DNA Source: UniProtKB
Keywordsi
Molecular function | Hydrolase |
Names & Taxonomyi
Protein namesi | Recommended name: 5'-deoxynucleotidase (EC:3.1.3.891 Publication)Alternative name(s): Deoxynucleoside-5'-monophosphatase Short name: 5'-dNMPase Protein dmp |
Gene namesi | Name:dmp ORF Names:T5.001Imported, T5p001Imported AND Name:T5p159Imported |
Organismi | Escherichia phage T5 (Enterobacteria phage T5) |
Taxonomic identifieri | 10726 [NCBI] |
Taxonomic lineagei | Viruses › Duplodnaviria › Heunggongvirae › Uroviricota › Caudoviricetes › Caudovirales › Demerecviridae › Markadamsvirinae › Tequintavirus |
Virus hosti | Escherichia coli [TaxID: 562] |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000165218 | 1 – 244 | 5'-deoxynucleotidaseAdd BLAST | 244 |
Expressioni
Inductioni
Expressed pre-early in the viral replicative cycle. Expressed with a few other proteins from the first step transfer (FST) DNA. FST DNA corresponds to the first small portion of the genome that enters into the host cell at the beginning of infection before pausing.1 Publication
Keywords - Developmental stagei
Early proteini Sequence
Sequence statusi: Complete.
Q38167-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNQVKTNITR NFPHISRVMI WDLDGTIINS FHRVAPCFDS EGNLDLNKYK
60 70 80 90 100
NEACKHDLIM QDTLLPLVTY MRQCMNDANT LNIICTARLM SKSDYYYLRK
110 120 130 140 150
QGLRGRGDSN IRVFSRDTLH KYFEADKVSE IYHSKDAVYK SYYFGLFKQL
160 170 180 190 200
YPNADFTMID DHKGVLSAAA SYGFKTLDAQ AVNDILSIGV TLIGETFIDE
210 220 230 240
SLEDDNDYQF LADRLQLCWE GMTEEERAEY SCSPQQYIEK LKVA
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 225 | E → K in AAU05298 (PubMed:24198424).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY543070 Genomic DNA Translation: AAS77048.1 AY692264 Genomic DNA Translation: AAU05154.1 AY692264 Genomic DNA Translation: AAU05298.1 AY587007 Genomic DNA Translation: AAX11938.1 AY587007 Genomic DNA Translation: AAX12089.1 X75922 Genomic DNA Translation: CAA53525.1 |
PIRi | S44989 |
RefSeqi | YP_006829.1, NC_005859.1 |
Genome annotation databases
GeneIDi | 2777573 |
KEGGi | vg:2777573 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY543070 Genomic DNA Translation: AAS77048.1 AY692264 Genomic DNA Translation: AAU05154.1 AY692264 Genomic DNA Translation: AAU05298.1 AY587007 Genomic DNA Translation: AAX11938.1 AY587007 Genomic DNA Translation: AAX12089.1 X75922 Genomic DNA Translation: CAA53525.1 |
PIRi | S44989 |
RefSeqi | YP_006829.1, NC_005859.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 2777573 |
KEGGi | vg:2777573 |
Family and domain databases
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DMP_BPT5 | |
Accessioni | Q38167Primary (citable) accession number: Q38167 Secondary accession number(s): Q66LQ4, Q6QGT6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 15, 1998 |
Last sequence update: | December 14, 2011 | |
Last modified: | December 2, 2020 | |
This is version 57 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |