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Protein
Submitted name:

Ras homolog family member G

Gene

Rhog

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activity Source: GO_Central
  • GTP binding Source: GO_Central
  • protein kinase binding Source: GO_Central

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-114604 GPVI-mediated activation cascade
R-RNO-194840 Rho GTPase cycle
R-RNO-416482 G alpha (12/13) signalling events
R-RNO-5625970 RHO GTPases activate KTN1
R-RNO-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Submitted name:
Ras homolog family member GImported
Submitted name:
Ras homolog gene family, member GImported
Submitted name:
Ras homolog gene family, member G (Rho G)Imported
Gene namesi
Name:RhogImported
ORF Names:rCG_39701Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi621310 Rhog

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000020393 Expressed in 10 organ(s), highest expression level in spleen

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ32PX6, 1 interactor
Q32PX6, 1 interactor
STRINGi10116.ENSRNOP00000027641

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0393 Eukaryota
COG1100 LUCA
GeneTreeiENSGT00760000118978
HOGENOMiHOG000233974
HOVERGENiHBG009351
KOiK07863
OMAiHCPDAPV
OrthoDBiEOG091G0KCM
TreeFamiTF101109

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51420 RHO, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q32PX6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQSIKCVVVG DGAVGKTCLL ICYTTNAFPK EYIPTVFDNY SAQSAVDGRT
60 70 80 90 100
VNLNLWDTAG QEEYDRLRTL SYPQTNVFVI CFSIASPPSY ENVRHKWHPE
110 120 130 140 150
VCHHCPDVPI LLVGTKKDLR AQPDTLRRLK EQGQAPITPQ QGQALAKQIH
160 170 180 190
AVRYLECSAL QQDGVKEVFA EAVRAVLNPT PIKRGRSCIL L
Length:191
Mass (Da):21,309
Last modified:December 6, 2005 - v1
Checksum:i0C4FE9C54140F499
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A096MK75A0A096MK75_RAT
Ras homolog family member G
Rhog
178Annotation score:
A0A096MJM1A0A096MJM1_RAT
Ras homolog family member G
Rhog
185Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07004912 Genomic DNA No translation available.
BC107943 mRNA Translation: AAI07944.1
CH473956 Genomic DNA Translation: EDM18196.1
RefSeqiNP_001032272.1, NM_001037195.1
XP_006229944.1, XM_006229882.3
XP_006229945.1, XM_006229883.3
UniGeneiRn.11976

Genome annotation databases

EnsembliENSRNOT00000027641; ENSRNOP00000027641; ENSRNOG00000020393
GeneIDi308875
KEGGirno:308875
UCSCiRGD:621310 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07004912 Genomic DNA No translation available.
BC107943 mRNA Translation: AAI07944.1
CH473956 Genomic DNA Translation: EDM18196.1
RefSeqiNP_001032272.1, NM_001037195.1
XP_006229944.1, XM_006229882.3
XP_006229945.1, XM_006229883.3
UniGeneiRn.11976

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ32PX6, 1 interactor
Q32PX6, 1 interactor
STRINGi10116.ENSRNOP00000027641

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000027641; ENSRNOP00000027641; ENSRNOG00000020393
GeneIDi308875
KEGGirno:308875
UCSCiRGD:621310 rat

Organism-specific databases

CTDi391
RGDi621310 Rhog

Phylogenomic databases

eggNOGiKOG0393 Eukaryota
COG1100 LUCA
GeneTreeiENSGT00760000118978
HOGENOMiHOG000233974
HOVERGENiHBG009351
KOiK07863
OMAiHCPDAPV
OrthoDBiEOG091G0KCM
TreeFamiTF101109

Enzyme and pathway databases

ReactomeiR-RNO-114604 GPVI-mediated activation cascade
R-RNO-194840 Rho GTPase cycle
R-RNO-416482 G alpha (12/13) signalling events
R-RNO-5625970 RHO GTPases activate KTN1
R-RNO-6798695 Neutrophil degranulation

Gene expression databases

BgeeiENSRNOG00000020393 Expressed in 10 organ(s), highest expression level in spleen

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51420 RHO, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ32PX6_RAT
AccessioniPrimary (citable) accession number: Q32PX6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: November 7, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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