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Protein

Histone H2A

Gene

LOC523631

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Histone H2AUniRule annotation
Gene namesi
Name:LOC523631Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome X

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleosome coreUniRule annotation, NucleusUniRule annotation

Expressioni

Gene expression databases

BgeeiENSBTAG00000037416 Expressed in 4 organ(s), highest expression level in testis

Interactioni

Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000051635

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 90HistoneInterPro annotationAdd BLAST85

Sequence similaritiesi

Belongs to the histone H2A family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1756 Eukaryota
COG5262 LUCA
GeneTreeiENSGT00910000143981
HOGENOMiHOG000234652
HOVERGENiHBG009342
KOiK11251
OMAiREGQFAN
OrthoDBiEOG091G14WU
TreeFamiTF300137

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR009072 Histone-fold
IPR002119 Histone_H2A
IPR007125 Histone_H2A/H2B/H3
PfamiView protein in Pfam
PF00125 Histone, 1 hit
PRINTSiPR00620 HISTONEH2A
SMARTiView protein in SMART
SM00414 H2A, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit

Sequencei

Sequence statusi: Complete.

Q32P61-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSPGRHLWNC RRSRRRSLSR STRAELQFPV SRVDRLLREG QFANRLSSAT
60 70 80 90 100
PVFLTGILEY LIANILDLAG KEACTNHRVR ISPEHVQTAL VNNENLRCLF
110
QPGAFSQPAA SPPAPEN
Length:117
Mass (Da):13,150
Last modified:December 6, 2005 - v1
Checksum:i09BF08ED9194200F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02073742 Genomic DNA No translation available.
BC108245 mRNA Translation: AAI08246.1
RefSeqiNP_001071426.1, NM_001077958.2
UniGeneiBt.63183

Genome annotation databases

EnsembliENSBTAT00000052785; ENSBTAP00000051635; ENSBTAG00000037416
GeneIDi523631
KEGGibta:523631

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02073742 Genomic DNA No translation available.
BC108245 mRNA Translation: AAI08246.1
RefSeqiNP_001071426.1, NM_001077958.2
UniGeneiBt.63183

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000051635

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000052785; ENSBTAP00000051635; ENSBTAG00000037416
GeneIDi523631
KEGGibta:523631

Phylogenomic databases

eggNOGiKOG1756 Eukaryota
COG5262 LUCA
GeneTreeiENSGT00910000143981
HOGENOMiHOG000234652
HOVERGENiHBG009342
KOiK11251
OMAiREGQFAN
OrthoDBiEOG091G14WU
TreeFamiTF300137

Gene expression databases

BgeeiENSBTAG00000037416 Expressed in 4 organ(s), highest expression level in testis

Family and domain databases

Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR009072 Histone-fold
IPR002119 Histone_H2A
IPR007125 Histone_H2A/H2B/H3
PfamiView protein in Pfam
PF00125 Histone, 1 hit
PRINTSiPR00620 HISTONEH2A
SMARTiView protein in SMART
SM00414 H2A, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ32P61_BOVIN
AccessioniPrimary (citable) accession number: Q32P61
Entry historyiIntegrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: September 12, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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